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  4. Recombinant Virulence sensor histidine kinase PhoQ (phoQ), partial

Recombinant Virulence sensor histidine kinase PhoQ (phoQ), partial

  • 中文名稱：
    傷寒沙門氏菌phoQ重組蛋白
  • 貨號：
    CSB-YP820645SWW1
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    傷寒沙門氏菌phoQ重組蛋白
  • 貨號：
    CSB-EP820645SWW1
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    傷寒沙門氏菌phoQ重組蛋白
  • 貨號：
    CSB-EP820645SWW1-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    傷寒沙門氏菌phoQ重組蛋白
  • 貨號：
    CSB-BP820645SWW1
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    傷寒沙門氏菌phoQ重組蛋白
  • 貨號：
    CSB-MP820645SWW1
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    phoQ
  • Uniprot No.：
  • 別名：
    phoQ; STY1270; t1690; Virulence sensor histidine kinase PhoQ; Sensor histidine protein kinase/phosphatase PhoQ
  • 種屬：
    Salmonella typhi
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Member of the two-component regulatory system PhoP/PhoQ which regulates the expression of genes involved in virulence and resistance to host defense antimicrobial peptides. In low periplasmic Mg(2+), PhoQ functions as a membrane-associated protein kinase that undergoes autophosphorylation and subsequently transfers the phosphate to PhoP, which results in the expression of PhoP-activated genes (PAG) and repression of PhoP-repressed genes (PRG). In high periplasmic Mg(2+), acts as a protein phosphatase that dephosphorylates phospho-PhoP, which results in the repression of PAG and may lead to expression of some PRG. Promotes intramacrophage survival of S.typhi. Is required to enhance bacterial resistance to bile in the human intestinal cells.
  • 基因功能參考文獻：
    1. PhoP/PhoQ's central role in Salmonella virulence PMID: 15948951
  • 亞細胞定位：
    Cell inner membrane; Multi-pass membrane protein.
  • 數(shù)據(jù)庫鏈接：

    KEGG: stt:t1690

    STRING: 220341.STY1270



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