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Recombinant Vaccinia virus Ribonucleoside-diphosphate reductase small chain (VACWR043)

  • 中文名稱:
    Recombinant Vaccinia virus Ribonucleoside-diphosphate reductase small chain (VACWR043)
  • 貨號:
    CSB-YP320834VAI
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Vaccinia virus Ribonucleoside-diphosphate reductase small chain (VACWR043)
  • 貨號:
    CSB-EP320834VAI
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Vaccinia virus Ribonucleoside-diphosphate reductase small chain (VACWR043)
  • 貨號:
    CSB-EP320834VAI-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Vaccinia virus Ribonucleoside-diphosphate reductase small chain (VACWR043)
  • 貨號:
    CSB-BP320834VAI
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Vaccinia virus Ribonucleoside-diphosphate reductase small chain (VACWR043)
  • 貨號:
    CSB-MP320834VAI
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    VACWR043
  • Uniprot No.:
  • 別名:
    VACWR043; F4L; Ribonucleoside-diphosphate reductase small chain; EC 1.17.4.1; Ribonucleotide reductase small subunit
  • 種屬:
    Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-319
  • 氨基酸序列
    MEPILAPNPN RFVIFPIQYY DIWNMYKKAE ASFWTVEEVD ISKDINDWNK LTPDEKYFIK HVLAFFAASD GIVNENLAER FCTEVQITEA RCFYGFQMAI ENIHSEMYSL LIDTYVKDSN EKNYLFNAIE TMPCVKKKAD WAQKWIHDSA GYGERLIAFA AVEGIFFSGS FASIFWLKKR GLMPGLTFSN ELISRDEGLH CDFACLMFKH LLHPPSEETV RSIITDAVSI EQEFLTAALP VKLIGMNCEM MKTYIEFVAD RLISELGFKK IYNVTNPFDF MENISLEGKT NFFEKRVGEY QKMGVMSQED NHFSLDVDF
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis. Allows virus growth in non-dividing cells. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  • 基因功能參考文獻:
    1. The F4L-deleted vaccinia viruses are highly attenuated in normal tissues, and since cancer cells commonly express elevated cell-cycle-regulated small subunit of ribonucleotide reductase (RRM2) levels, have tumor-selective replication and cell killing. PMID: 28289079
    2. poxvirus R2 subunits form functional complexes with host R1 subunits to provide sufficient dNTPs for viral replication. PMID: 20628573
  • 蛋白家族:
    Ribonucleoside diphosphate reductase small chain family
  • 數據庫鏈接:

    KEGG: vg:3707500



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