在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Thrixopelma pruriens Beta/omega-theraphotoxin-Tp2a

Recombinant Thrixopelma pruriens Beta/omega-theraphotoxin-Tp2a

  • 中文名稱：
    Recombinant Thrixopelma pruriens Beta/omega-theraphotoxin-Tp2a
  • 貨號：
    CSB-YP307360TEF
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Thrixopelma pruriens Beta/omega-theraphotoxin-Tp2a
  • 貨號：
    CSB-EP307360TEF
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Thrixopelma pruriens Beta/omega-theraphotoxin-Tp2a
  • 貨號：
    CSB-EP307360TEF-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Thrixopelma pruriens Beta/omega-theraphotoxin-Tp2a
  • 貨號：
    CSB-BP307360TEF
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Thrixopelma pruriens Beta/omega-theraphotoxin-Tp2a
  • 貨號：
    CSB-MP307360TEF
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    N/A
  • Uniprot No.：
  • 別名：
    Beta/omega-theraphotoxin-Tp2a; Beta/omega-TRTX-Tp2a; Protoxin-2; ProTx-2; ProTx2; Protoxin-II; PT-II; ProTx-II
  • 種屬：
    Thrixopelma pruriens (Peruvian green velvet tarantula)
  • 蛋白長度：
    Cytoplasmic domain
  • 表達(dá)區(qū)域：
    1-30
  • 氨基酸序列
    YCQKWMWTCD SERKCCEGMV CRLWCKKKLW
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Gating-modifier toxin that targets voltage-gated sodium channels with a selective activity on Nav1.7/SCN9A (IC(50)=1-1.5 nM). It inhibits both activation and inactivation. For inhibition of activation, it is 100-fold more selective for Nav1.7/SCN9A (IC(50)=0.26-3) than for other sodium channels (Nav1.2/SCN2A (IC(50)=40-540 nM), Nav1.3/SCN3A (IC(50)=102 nM), Nav1.4/SCN4A (IC(50)=30-39 nM), Nav1.5/SCN5A (IC(50)=19-90 nM), Nav1.6/SCN8A (IC(50)=26 nM), and Nav1.8/SCN10A (IC(50)=146 nM)). For inhibition of inactivation, it is 20-fold more potent in inhibiting inactivation on Nav1.7/SCN9A (IC(50)=250 nM) than other channels (about 4.6 uM for all channels). It also weakly inhibits Cav1.2/CACNA1C and Cav3.2/CACNA1H (29% block at 1 uM). It inhibits Nav1.7/SCN9A activation by interacting with DII and impairs Nav1.7/SCN9A inactivation by interacting with DIV. It docks on top of the DII S3 helix Nav1.7/SCN9A. It is about 60-fold less active on Nav1.7/SCN9A at depolarized potential (0 mV; IC(50)=15 nM), compared to -120 mV potential (IC(50)=0.26 nM). This toxin binds to lipid membrane. This ability correlates with hNav1.7/SCN9A inhibition, showing that membrane binding is the first step in the inhibitory mechanism of this toxin. It inhibits Nav1.2/SCN2A less potently when it is coexpressed with SCN2B or SCN4B than when it is expressed alone, showing that beta subunits (SCN2B and SCN4B) have a protective effect.
  • 亞細(xì)胞定位：
    Secreted.
  • 蛋白家族：
    Phrixotoxin family
  • 組織特異性：
    Expressed by the venom gland.


主站蜘蛛池模板： 亚洲日韩中文字幕久热| 大陆精大陆国产国语精品 | 国产性夜夜春夜夜爽1a片| 免费香蕉成视频人网站| 人人妻人人澡人人爽欧美精品| 天天躁日日躁aaaaxxxx| 午夜无码一区二区三区在线观看| 人妻少妇久久中文字幕456| 无码中出人妻中文字幕av| 男女啪啪网站大全免费| 无码人妻aⅴ一区二区三区| 国产亚洲欧美日韩夜色凹凸成人 | 孕妇怀孕高潮潮喷视频孕妇 | 中文字幕av无码不卡免费| av大尺度一区二区三区| av老司机亚洲精品天堂| 麻豆国产va免费精品高清在线| 中文字幕无码热在线视频| 在线观看无码av免费不卡软件| 中文字幕人成乱码熟女免费 | 摸丰满大乳奶水www免费| 亚洲高清有码中文字| 蜜臀少妇人妻在线| 99国产精品久久久久久久成人热| 老妇肥熟凸凹丰满刺激| 成人免费午夜无码视频在线播放| 国产在线观看www污污污| 性生交大片免费看女人按摩| 久精品国产欧美亚洲色aⅴ大片| 人妻少妇无码精品专区| 极品新婚夜少妇真紧| 免费国产又色又爽又黄的网站| 婷婷丁香五月六月综合激情啪| 人妻无码熟妇乱又伦精品视频| 精品国产制服丝袜高跟| 中文日韩亚洲欧美制服| 色综合天天综合欧美综合| 亚洲视频一区| 色情久久久av熟女人妻网站| 亚洲熟妇av一区二区三区浪潮| 内射爽无广熟女亚洲|