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  4. Recombinant Schizosaccharomyces pombe Meiosis-specific serine/threonine-protein kinase mek1 (mek1)

Recombinant Schizosaccharomyces pombe Meiosis-specific serine/threonine-protein kinase mek1 (mek1)

  • 中文名稱：
    龐貝裂殖酵母mek1重組蛋白
  • 貨號：
    CSB-YP608771SXV
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    龐貝裂殖酵母mek1重組蛋白
  • 貨號：
    CSB-EP608771SXV
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    龐貝裂殖酵母mek1重組蛋白
  • 貨號：
    CSB-EP608771SXV-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    龐貝裂殖酵母mek1重組蛋白
  • 貨號：
    CSB-BP608771SXV
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    龐貝裂殖酵母mek1重組蛋白
  • 貨號：
    CSB-MP608771SXV
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    mek1
  • Uniprot No.：
  • 別名：
    mek1; SPAC14C4.03Meiosis-specific serine/threonine-protein kinase mek1; EC 2.7.11.1
  • 種屬：
    Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-445
  • 氨基酸序列
    MDFLSHAMLS RSESTQILCE LSQIDESTMD PQYTEDDVLA RLFVFSSSSP QTVLNVKKYE DVSVGRSNTC NYQLLQFTAS YKHFRVYSVL IDDDMDPLVY CEDQSSNGTF LNHRLIGKGN SVLLSDGDIL DVRHCASFLF QQKYTTDNDF HHEYAGERFN ITQRLLGIGG FSRIYMAMDN NTGGQYACKI IDKKKISTKR FFEDHEMTIL RKLDHPNIIK VNMEYNSETQ FFIFEEMVTG GDLFSYLTKL GTVPEVTTLF IMFQILQGLK YLHEQNIIHR DLKLENILIA SSSDTIFRII LTDFGVARCM QKGKRLSTFV GTPEYTAPEI QRLKGRSQVE KENSSGYGKE VDLWSLGVIM FLLLSGNSPS FADGVKEKQV DFRDPVWKSV SRQAKDLISN LLKTNPPDRF TVKQCLSHPW FARHSSRLTK LYETRILKPL KHSRL
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Probable protein kinase required for meiotic recombination.
  • 基因功能參考文獻：
    1. MEK1 phosphorlated by Rad3 and/or Tel1 on the S12, S14, ST15 residues, and that these modifications are required for meiotic progression. PMID: 21084840
    2. This work demonstrates that Mek1 is activated in response to double-strand breaks by autophosphorylation of two conserved threonines, T327 and T331, in the Mek1 activation loop. PMID: 17526735
    3. Mek1 acts independently of Cds1 to phosphorylate Cdc25, and this phosphorylation is required to trigger cell cycle arrest. PMID: 19029820
  • 蛋白家族：
    Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHEK2 subfamily
  • 數據庫鏈接：


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