在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rat Sterol regulatory element-binding protein 2 (Srebf2), partial

Recombinant Rat Sterol regulatory element-binding protein 2 (Srebf2), partial

  • 中文名稱：
    大鼠Srebf2重組蛋白
  • 貨號：
    CSB-YP660998RA1
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    大鼠Srebf2重組蛋白
  • 貨號：
    CSB-EP660998RA1
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    大鼠Srebf2重組蛋白
  • 貨號：
    CSB-EP660998RA1-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    大鼠Srebf2重組蛋白
  • 貨號：
    CSB-BP660998RA1
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    大鼠Srebf2重組蛋白
  • 貨號：
    CSB-MP660998RA1
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Srebf2; Sterol regulatory element-binding protein 2; SREBP-2; Sterol regulatory element-binding transcription factor 2
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Precursor of the transcription factor form (Processed sterol regulatory element-binding protein 2), which is embedded in the endoplasmic reticulum membrane. Low sterol concentrations promote processing of this form, releasing the transcription factor form that translocates into the nucleus and activates transcription of genes involved in cholesterol biosynthesis.; Key transcription factor that regulates expression of genes involved in cholesterol biosynthesis. Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3'). Regulates transcription of genes related to cholesterol synthesis pathway.
  • 基因功能參考文獻：
    1. SREBP2, which can be modulated by the impairment of cerebral cholesterol homeostasis, has a direct role on BACE1 expression PMID: 21726644
    2. prior to weaning, SREBP-2 is proteolytically processed to the mature form PMID: 12488438
    3. Overexpression of the SREBP processing system contributed to the activation of LXRalpha by maintaining high oxysterol levels in tissue. PMID: 16941710
    4. Results indicate that the rapid induction of the hepatic LDL receptor by thyroid hormone is likely due to direct interaction with thyroid response elements rather than indirectly by a mechanism involving SREBP-2. PMID: 17572141
    5. reduced cholesterol concentrations in liver and plasma of rats administered an oxidized oil were due to an inhibition of the activation of SREBP-2 PMID: 17709436
    6. nephrotic hypercholesterolemia may be associated with dysregulation of hepatic tissue SREBP-2 PMID: 17884448
    7. Taken together, the above results show that there is high level of SREBP-2 expression in the normal hippocampus, and that neuronal injury results in a significant reduction of SREBP-2 expression in the damaged areas. PMID: 19124072
    8. Results describe the characterization of a novel isoform of the transcription factor SREBP2, which is highly enriched in spermatogenic cells, is expressed in a stage-dependent fashion, and is not subject to feedback control by sterols. PMID: 12446768
    9. data indicate that polyunsaturated fatty acids (PUFA) suppress the in vivo proteolytic release of sterol regulatory element binding proteins-1 and -2, but the effect on SREBP-2 is transitory. PMID: 12421847
    10. Studies indicate that, prior to weaning, SREBP-2 but not SREBP-1 is proteolytically processed to the mature form. PMID: 12488438

    顯示更多

    收起更多

  • 亞細胞定位：
    [Sterol regulatory element-binding protein 2]: Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein.; [Processed sterol regulatory element-binding protein 2]: Nucleus.
  • 蛋白家族：
    SREBP family
  • 數據庫鏈接：


主站蜘蛛池模板： 老司机性色福利精品视频| 护士脱了内裤让我爽了一夜视频 | 午夜肉伦伦影院| 久久婷婷五月综合中文字幕| 性饥渴少妇av无码毛片| 人妻 色综合网站| 精品国产综合区久久久久久| 久久久久久人妻毛片a片| 国产精品∧v在线观看| 久久综合久久久久88| 国产精品丝袜久久久久久不卡| 免费网禁国产you女网站下载| 成人免费无码大片a毛片小说| 国产麻豆一精品一av一免费 | 无码av免费精品一区二区三区| 欧美熟妇丰满肥白大屁股免费视频 | 蜜桃网站入口可看18禁| 成人爽a毛片在线视频| 香港三日本三级少妇三级66| 在线中文字幕乱码英文字幕正常 | 国产精品一久久香蕉国产线看观看| 中文人妻无码一区二区三区信息| 亚洲欧美日本中文字不卡| 亚洲欧洲国产成人综合在线观看| 精品国产三级在线观看| 精品国产杨幂在线观看| 在线无码av一区二区三区| 欧美 日韩 国产 成人 在线观看 | 日韩在线 | 中文| 伊人久久精品一区二区三区| 亚洲乱亚洲乱妇| 中国少妇内射xxxhd| 深夜福利小视频在线观看| 精品产区wnw2544| 色综合天天视频在线观看| 国产l精品国产亚洲区| 欧美极品少妇无套实战| 野狼第一精品社区| 无码人妻久久1区2区3区| 日日夜夜撸啊撸| 国产精品亚洲专区无码web|