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  4. Recombinant Rat Proton-coupled folate transporter (Slc46a1), partial

Recombinant Rat Proton-coupled folate transporter (Slc46a1), partial

  • 中文名稱：
    大鼠Slc46a1重組蛋白
  • 貨號(hào)：
    CSB-YP685742RA
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    大鼠Slc46a1重組蛋白
  • 貨號(hào)：
    CSB-EP685742RA
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    大鼠Slc46a1重組蛋白
  • 貨號(hào)：
    CSB-EP685742RA-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    大鼠Slc46a1重組蛋白
  • 貨號(hào)：
    CSB-BP685742RA
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    大鼠Slc46a1重組蛋白
  • 貨號(hào)：
    CSB-MP685742RA
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Slc46a1
  • Uniprot No.：
  • 別名：
    Slc46a1; Hcp1; Pcft; Proton-coupled folate transporter; Heme carrier protein 1; PCFT/HCP1; Solute carrier family 46 member 1
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Proton-coupled high-affinity folate and heme transporter that plays an essential role in iron metabolism. Acts as the main importer of heme in the intestine. Imports also heme in the retina and retinal pigment epithelium, in neurons of the hippocampus, and in the renal epithelial cells. Participates therefore in the trafficking of heme and increases intracellular iron content. Mediates also intestinal absorption of folates and their transport from blood to cerebrospinal fluid across the choroid plexus.
  • 基因功能參考文獻(xiàn)：
    1. Data suggest that the malabsorption of folate in the colon associated with alcoholism is due, in part, to down-regulation of folate transporter expression and association with lipid rafts (for both PCFT/Slc46a1 and reduced folate carrier/Slc19a1). PMID: 21861943
    2. we provide several lines of evidence that indicate PCFT/HCP1 has a role as the molecular entity of the intestinal folate transport system. PMID: 18174275
    3. Slc46a1/PCFT plays critical role in intestinal folate absorption. PMID: 17898134
  • 亞細(xì)胞定位：
    Apical cell membrane; Multi-pass membrane protein. Cytoplasm.
  • 蛋白家族：
    Major facilitator superfamily, SLC46A family
  • 組織特異性：
    Expressed at low level in liver.
  • 數(shù)據(jù)庫(kù)鏈接：


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