在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rat Leucine-rich repeat-containing protein 8A (Lrrc8a), partial

  • 中文名稱:
    大鼠Lrrc8a重組蛋白
  • 貨號:
    CSB-YP709281RA
  • 說明書:
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    大鼠Lrrc8a重組蛋白
  • 貨號:
    CSB-EP709281RA
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    大鼠Lrrc8a重組蛋白
  • 貨號:
    CSB-EP709281RA-B
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    大鼠Lrrc8a重組蛋白
  • 貨號:
    CSB-BP709281RA
  • 說明書:
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    大鼠Lrrc8a重組蛋白
  • 貨號:
    CSB-MP709281RA
  • 說明書:
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Lrrc8a; Lrrc8; Volume-regulated anion channel subunit LRRC8A; Leucine-rich repeat-containing protein 8A
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and can also conduct organic osmolytes like taurine. Mediates efflux of amino acids, such as aspartate and glutamate, in response to osmotic stress. In complex with LRRC8C or LRRC8E, acts as a transporter of immunoreactive cyclic dinucleotide GMP-AMP (2'-3'-cGAMP), an immune messenger produced in response to DNA virus in the cytosol: mediates both import and export of 2'-3'-cGAMP, thereby promoting transfer of 2'-3'-cGAMP to bystander cells. In contrast, complexes containing LRRC8D inhibit transport of 2'-3'-cGAMP. Required for in vivo channel activity, together with at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition. Can form functional channels by itself (in vitro). Involved in B-cell development: required for the pro-B cell to pre-B cell transition. Also required for T-cell development. Required for myoblast differentiation: VRAC activity promotes membrane hyperpolarization and regulates insulin-stimulated glucose metabolism and oxygen consumption. Also acts as a regulator of glucose-sensing in pancreatic beta cells: VRAC currents, generated in response to hypotonicity- or glucose-induced beta cell swelling, depolarize cells, thereby causing electrical excitation, leading to increase glucose sensitivity and insulin secretion. Also plays a role in lysosome homeostasis by forming functional lysosomal VRAC channels in response to low cytoplasmic ionic strength condition: lysosomal VRAC channels are necessary for the formation of large lysosome-derived vacuoles, which store and then expel excess water to maintain cytosolic water homeostasis.
  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein.
  • 蛋白家族:
    LRRC8 family
  • 數據庫鏈接:


主站蜘蛛池模板: 太粗太深了太紧太爽了动态图男男| 国产成人综合在线女婷五月99播放| 黑人强伦姧人妻久久| 97人摸人人澡人人人超碰| 少妇中文字幕乱码亚洲影视| 乱码丰满人妻一二三区| 9久9久女女热精品视频在线观看| 国产麻豆精品福利在线观看| 亚洲国产精品嫩草影院| 日韩免费特黄一二三区| 欧美 日产 国产在线观看| 亚洲国产成人无码精品| 国产日韩一区二区三免费高清| 俄罗斯大荫蒂女人毛茸茸| 色婷婷狠狠97成为人免费| 99精品国产综合久久久久五月天| 久久亚洲春色中文字幕久久久| 国产mv在线天堂mv免费观看 | 欧洲性久久精品| 亚洲v国产v天堂a无码二区| 少妇高潮大叫好爽| 男女性杂交内射女bbwxz| 国产精品 自在自线| 亚洲国产成人精品无码区一本| 中文字幕乱码人妻无码久久| 久久久亚洲欧洲日产国码606| 韩国三级无码hd中文字幕| 放荡的少妇2欧美版| 97久久精品无码一区二区| 久久亚洲精品中文字幕一区| 亚洲伊人久久精品影院| 国产乱人激情h在线观看| 麻豆果冻国产剧情av在线播放| 2018av无码视频在线播放| 精精国产xxxx视频在线| 亚洲中文字幕精品久久久久久动漫| 天堂在/线资源中文在线8| 男女无遮挡激情视频| 性一交一乱一色一视频| 亚洲国产成人精品无码区花野真一| 小宝极品内射国产在线|