在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rat Gremlin-1 (Grem1)

Recombinant Rat Gremlin-1 (Grem1)

  • 中文名稱：
    大鼠Grem1重組蛋白
  • 貨號：
    CSB-YP009892RA
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    大鼠Grem1重組蛋白
  • 貨號：
    CSB-EP009892RA-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Grem1; Cktsf1b1; Drm; Gremlin-1; Cysteine knot superfamily 1; BMP antagonist 1; Down-regulated in Mos-transformed cells protein
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區(qū)域：
    25-184
  • 氨基酸序列
    KKKGSQ GAIPPPDKAQ HNDSEQTQSP PQPGSRTRGR GQGRGTAMPG EEVLESSQEA LHVTERKYLK RDWCKTQPLK QTIHEEGCNS RTIINRFCYG QCNSFYIPRH IRKEEGSFQS CSFCKPKKFT TMMVTLNCPE LQPPTKKKRV TRVKQCRCIS IDLD
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner. Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro). Acts as inhibitor of monocyte chemotaxis. Can inhibit the growth or viability of normal cells but not transformed cells when is overexpressed.
  • 基因功能參考文獻：
    1. gremlin1 promotes hepatic stellate cell activation and hepatic fibrogenesis through impairment of the balance between transforming growth factor beta and bone morphogenetic protein 7 signaling pathways. PMID: 27863390
    2. The therapeutic mechanism of Danshao Huaxian capsule in hepatic fibrosis may be associated with inhibition of the expression of Gremlin and up-regulation of the expression of BMP-7. PMID: 25356047
    3. GREM1 affects follicle transition in cultured ovaries, but is not normally present in primordial and early-stage developing follicles. PMID: 24614542
    4. Notch pathway gene expression is elevated in diabetic nephropathy, co-incident with Gremlin, and may contribute to the pathogenesis of this dise PMID: 17980714
    5. Gremlin plays a part in the development of pathological phenotypic changes of adult vascular smooth muscle cell. PMID: 18086474
    6. The bone morphogenetic protein antagonist gremlin promotes vascular smooth muscle cell apoptosis. PMID: 19142012

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    DAN family
  • 組織特異性：
    Highly expressed in the brain, kidney, spleen, and testis and weakly expressed in the lung and liver. Predominantly expressed in differentiated cells as neurons in brain, type I cells in lung and globlet cells in intestine.
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 亚洲精品国产成人| 亚洲国产精品久久久久秋霞小说| 亚洲精品成人福利网站app| av人摸人人人澡人人超碰妓女| 日本55丰满熟妇厨房伦| 综合久久国产九一剧情麻豆| 大狠狠大臿蕉香蕉大视频| 男女下面一进一出无遮挡 | 国产精品系列无码专区| 国产精品无码专区| 国产综合精品| 18禁区美女免费观看网站| 国产精品天天看特色大片| 天天躁日日躁狠狠躁av麻豆男男| 少妇精品导航| 99re8精品视频热线观看| 四虎成人精品一区二区免费网站 | 色翁荡熄又大又硬又粗又视频| 人人爽人人爽人人片a| 少妇被黑人4p到惨叫欧美人| 国产精品天干天干| 日本中国内射bbxx| 国产亚洲福利在线视频| 亚洲成年轻人电影网站www| 国产午夜亚洲精品午夜鲁丝片| 影音先锋男人站| 欧美性video高清精品| 国产人妻久久精品一区二区三区| 色一情一区二区三区四区| 动漫人妻h无码中文字幕| 亚洲伦无码中文字幕另类 | 久久性色av亚洲电影| 在线永久免费观看黄网站| 免费女人裸体视频无遮挡免费网站| 欧美极品色午夜在线视频| 久久精品www人人爽人人| 欧美日韩精品一区二区视频| 在线精品国精品国产尤物| 国产又色又爽又刺激在线观看 | 又大又黄又粗又爽的免费视频| 国产成人无码免费视频麻豆|