在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Protein E7 (E7)

  • 中文名稱:
    Recombinant Protein E7(E7)
  • 貨號(hào):
    CSB-YP361838HMP
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Protein E7(E7)
  • 貨號(hào):
    CSB-EP361838HMP
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Protein E7(E7)
  • 貨號(hào):
    CSB-EP361838HMP-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Protein E7(E7)
  • 貨號(hào):
    CSB-BP361838HMP
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Protein E7(E7)
  • 貨號(hào):
    CSB-MP361838HMP
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    E7; Protein E7
  • 種屬:
    Human papillomavirus type 1a
  • 蛋白長(zhǎng)度:
    full length protein
  • 表達(dá)區(qū)域:
    1-93
  • 氨基酸序列
    MVGEMPALKD LVLQLEPSVL DLDLYCYEEV PPDDIEEELV SPQQPYAVVA SCAYCEKLVR LTVLADHSAI RQLEELLLRS LNIVCPLCTL QRQ
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. Plays also a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha. Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
  • 基因功能參考文獻(xiàn):
    1. novel zinc-bound E7-CR3 obligate homodimer has two surface patches of sequence conservation, mutation of these patches reveals that one patch is required for pRb binding, whereas the other is required for E2F binding PMID: 16249186
    2. Collectively, these data support the notion that p130 controls the homeostasis of the differentiated keratinocytes and is therefore targeted by E7 for degradation to establish conditions permissive for viral DNA amplification. PMID: 18321970
    3. caspase cleavage is induced upon differentiation of HPV positive cells through the action of the DNA damage protein kinase CHK2, which may be activated as a result of E7 binding to the ATM kinase. PMID: 19798429
  • 亞細(xì)胞定位:
    Host cytoplasm. Host nucleus.
  • 蛋白家族:
    Papillomaviridae E7 protein family
  • 數(shù)據(jù)庫(kù)鏈接:

    KEGG: vg:1489171



主站蜘蛛池模板: 久久www香蕉免费人成| 秋霞影院午夜伦a片欧美| 国产精品美女久久久网av| 亚洲一区二区女搞男| 日本天天黄网站| 久久精品中文字幕有码| 国产午夜精品一区二区三区不卡| 丁香五月亚洲综合在线| 久久久久免费看成人影片| 青青草国产免费久久久| 加勒比中文无码久久综合色| 国产95在线 | 亚洲| 精品www日韩熟女人妻| 日本理论片午午伦夜理片2021| 精品露脸国产偷人在视频| 久久精品国产99精品国产亚洲性色| 欧美大屁股xxxx高跟欧美黑人 | 中文字幕婷婷日韩欧美亚洲 | 欧美精品v国产精品v日韩精品| 欧洲美熟女乱又伦| 国产精品久久精品国产| 中文国产乱码在线人妻一区二区| 亚洲欧美日韩综合一区在线| 国产99久久久欧美黑人刘玥| 国产精品成人va在线观看| 男女同房做爰爽免费| 肥白大屁股bbwbbwhd| 人禽伦免费交视频播放| 人妻少妇heyzo无码专区| 久久精品香蕉绿巨人登场| 777午夜精品免费观看| 使劲快高潮了国语对白在线| 丰满护士巨好爽好大乳| 欧美日韩精品一区二区在线视频 | 十八禁av无码免费网站| 亚洲欧美国产精品久久久久久久| 在线 偷窥 制服 另类 | 国产日韩未满十八禁止观看| 早起邻居人妻奶罩太松av | 羞涩的丰满人妻40p| 亚洲精品无码专区|