在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Pongo abelii Ubiquitin-conjugating enzyme E2 D3 (UBE2D3)

  • 中文名稱:
    波戈阿貝利UBE2D3重組蛋白
  • 貨號:
    CSB-YP725260PYX
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    波戈阿貝利UBE2D3重組蛋白
  • 貨號:
    CSB-EP725260PYX
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    波戈阿貝利UBE2D3重組蛋白
  • 貨號:
    CSB-EP725260PYX-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    波戈阿貝利UBE2D3重組蛋白
  • 貨號:
    CSB-BP725260PYX
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    波戈阿貝利UBE2D3重組蛋白
  • 貨號:
    CSB-MP725260PYX
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    UBE2D3; Ubiquitin-conjugating enzyme E2 D3; EC 2.3.2.23;; E3-independent) E2 ubiquitin-conjugating enzyme D3; EC 2.3.2.24; E2 ubiquitin-conjugating enzyme D3; Ubiquitin carrier protein D3; Ubiquitin-protein ligase D3
  • 種屬:
    Pongo abelii (Sumatran orangutan)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-147
  • 氨基酸序列
    MALKRINKEL SDLARDPPAQ CSAGPVGDDM FHWQATIMGP NDSPYQGGVF FLTIHFPTDY PFKPPKVAFT TRIYHPNINS NGSICLDILR SQWSPALTIS KVLLSICSLL CDPNPDDPLV PEIARIYKTD RDKYNRISRE WTQKYAM
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-, as well as 'Lys-48'-linked polyubiquitination. Cooperates with the E2 CDC34 and the SCF(FBXW11) E3 ligase complex for the polyubiquitination of NFKBIA leading to its subsequent proteasomal degradation. Acts as an initiator E2, priming the phosphorylated NFKBIA target at positions 'Lys-21' and/or 'Lys-22' with a monoubiquitin. Ubiquitin chain elongation is then performed by CDC34, building ubiquitin chains from the UBE2D3-primed NFKBIA-linked ubiquitin. Acts also as an initiator E2, in conjunction with RNF8, for the priming of PCNA. Monoubiquitination of PCNA, and its subsequent polyubiquitination, are essential events in the operation of the DNA damage tolerance (DDT) pathway that is activated after DNA damage caused by UV or chemical agents during S-phase. Associates with the BRCA1/BARD1 E3 ligase complex to perform ubiquitination at DNA damage sites following ionizing radiation leading to DNA repair. Targets DAPK3 for ubiquitination which influences promyelocytic leukemia protein nuclear body (PML-NB) formation in the nucleus. In conjunction with the MDM2 and TOPORS E3 ligases, functions ubiquitination of p53/TP53. Supports NRDP1-mediated ubiquitination and degradation of ERBB3 and of BRUCE which triggers apoptosis. In conjunction with the CBL E3 ligase, targets EGFR for polyubiquitination at the plasma membrane as well as during its internalization and transport on endosomes. In conjunction with the STUB1 E3 quality control E3 ligase, ubiquitinates unfolded proteins to catalyze their immediate destruction. Together with RNF135, catalyzes the viral RNA-dependent 'Lys-63'-linked polyubiquitination of RIG-I/DDX58 to activate the downstream signaling pathway that leads to interferon beta production.
  • 亞細胞定位:
    Cell membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.
  • 蛋白家族:
    Ubiquitin-conjugating enzyme family
  • 數據庫鏈接:


主站蜘蛛池模板: 热re99久久精品国产66热| 国产成人无码午夜视频在线观看| 亚洲最大的成人网| 人妻另类 专区 欧美 制服| 中文字日产乱码免费1~3软件| 精品无码乱码av| 日本一卡2卡3卡4卡无卡免费网站| 四虎国产精品永久在线| 伊人色综合网一区二区三区 | 2012中文字幕在线视频| 国产精品丝袜亚洲熟女| 成 人 网 站 免费观看| 内射无码专区久久亚洲| 丝袜美腿丝袜亚洲综合| 亚洲成aⅴ人最新无码| 国产在线视频一区二区三区| 国产精品人妻| 国产真实偷乱视频| 最美女人体内射精一区二区 | 又黄又爽又无遮挡免费的网站| 亚洲精品日本一区二区三区| 在线亚洲中文精品第1页| 三个男吃我奶头一边一个视频| 亚洲精品乱码久久久久红杏| 亚洲日本在线在线看片| 久久精晶国产99久久6| 奇米影视888欧美在线观看| 亚洲精品日本一区二区三区| 亚洲精品久久久久中文字幕m男 | 99久久人妻精品免费二区| 少妇做爰又色又紧夜视频| 中文字幕av无码专区第一页| 人妻丰满熟妇av无码区免 | 国产精品久久久久久不卡盗摄| 天天拍天天看天天做| 日韩精品一区二区av在线观看| av第一福利网站| 国色天香中文字幕在线视频| 好了av四色综合无码久久| 精品无码久久久久久尤物| 欧美国产一区二区三区激情无套|