在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Macrosialin (Cd68), partial

  • 中文名稱:
    Recombinant Mouse Macrosialin(Cd68),partial
  • 貨號:
    CSB-YP004951MO
  • 規格:
    ¥2208
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    Cd68; Macrosialin; CD antigen CD68
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Extracellular Domain
  • 來源:
    Yeast
  • 分子量:
    30.8 kDa
  • 表達區域:
    21-291aa
  • 氨基酸序列
    DCPHKKAVTLLPSFTMTPTATESTASPTTSHRPTTTSHGNVTVHTSSGPTTVTHNPATTTSHGNATISHATVSPTTNGTATSPRSSTVGPHPGPPPPSPSPRSKGALGNYTWANGSQPCVQLQAQIQIRILYPIQGGRKAWGISVLNPNKTKVQGGCDGTHPHLSLSFPYGQLTFGFKQDLHQSPSTVYLDYMAVEYNVSFPQAAQWTFMAQNSSLRELQAPLGQSFCCGNASIVLSPAVHLDLLSLRLQAAQLPDKGHFGPCFSCNRDQS
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Tris-based buffer,50% glycerol
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
  • 基因功能參考文獻:
    1. Findings indicate that human CD68 and its mouse ortholog macrosialin located in the lysosomal membrane and share many structural similarities. PMID: 27869795
    2. Myeloid osteoclast precursors do not express CD68. PMID: 28173622
    3. CD68, a putative receptor for sporozoite invasion of Kupffer cells that acts as a gateway for malaria infection of the liver. PMID: 26216124
    4. Results showed that activated microglia in Alzheimer's disease-like mice showed two-step transition: a CD68-negative activated form at 6-9 months and a CD68-positive form from 12 months of age PMID: 25352454
    5. Statins promote the beneficial remodeling of plaques in diseased mouse arteries through the stimulation of the CCR7 / CD68 emigration pathway in macrophages PMID: 22163030
    6. These findings demonstrate a role for CD68 in the function of osteoclasts. PMID: 21991369
    7. CD68-null mononuclear phagocytes exhibited a trend toward enhanced antigen presentation to CD4+ T cells, indicating that CD68 may function to negatively regulate antigen uptake, loading, or major histocompatibility complex class II trafficking. PMID: 21572087
    8. Atherogenic diet-induced reduction in lipid levels of Reversa model mouse leads to decreased monocyte-derived CD68-positive cells in advanced atherosclerotic plaques and is associated with emigration of these cells from the atherosclerotic plaques. PMID: 21339485
    9. Macrosialin does not function as an oxLDL receptor on the cell surface. PMID: 12562841
    10. Data show that macrosialin (CD68), a macrophage-specific protein, is increased by aging in selected brain regions of male C57BL/6NNia mice. PMID: 16157452

    顯示更多

    收起更多

  • 亞細胞定位:
    [Isoform Long]: Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein.; [Isoform Short]: Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    LAMP family
  • 組織特異性:
    Expressed in tissue macrophages and to a lesser extent in dendritic cells.
  • 數據庫鏈接:


主站蜘蛛池模板: 国自产拍偷拍精品啪啪一区二区| r级无码视频在线观看| 欧美成人看片一区二区三区尤物| 极品尤物被啪到呻吟喷水| 天天躁日日摸久久久精品| 国产做爰xxxⅹ高潮视频12p| 国产成人无码免费视频在线 | 中文字幕无码av正片| 国产精品国产对白熟妇| av大片在线无码免费| 99国产精品久久久久久久成人热| 欧美自拍嘿咻内射在线观看| www.-级毛片线天内射视视| 狠狠躁夜夜躁人人爽天天古典 | 又粗又黑又大的吊av| 黑人大荫蒂高潮视频| 久在线精品视频线观看| 一道精品视频一区二区三区| 婷婷成人五月综合激情| 上司的丰满人妻中文字幕| 国产99久久久久久免费看| 伊人久久大香线蕉综合直播| 被技师按摩到高潮的少妇| 国产精品亚洲а∨天堂123| 久久99精品久久只有精品| 浮妇高潮喷白浆视频| 国产成人无码av片在线观看不卡| 女人夜夜春高潮爽a∨片| 884aa四虎影成人精品| 免费无码黄网站在线看| 337p日本欧洲亚洲大胆色噜噜| 秋秋影视午夜福利高清| 国产高清在线精品一区免费| 亚洲 小说区 图片区 都市| 色窝窝无码一区二区三区| 亚洲国内精品自在线影院| 日本高清www无色夜在线视频| 国产老妇伦国产熟女老妇高清 | 国产亚洲成av人片在线观看| 无码av免费一区二区三区四区| 亚洲一区二区av在线观看|