在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Macrosialin (Cd68), partial

  • 中文名稱:
    Recombinant Mouse Macrosialin(Cd68),partial
  • 貨號:
    CSB-YP004951MO
  • 規格:
    ¥2208
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    Cd68; Macrosialin; CD antigen CD68
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Extracellular Domain
  • 來源:
    Yeast
  • 分子量:
    30.8 kDa
  • 表達區域:
    21-291aa
  • 氨基酸序列
    DCPHKKAVTLLPSFTMTPTATESTASPTTSHRPTTTSHGNVTVHTSSGPTTVTHNPATTTSHGNATISHATVSPTTNGTATSPRSSTVGPHPGPPPPSPSPRSKGALGNYTWANGSQPCVQLQAQIQIRILYPIQGGRKAWGISVLNPNKTKVQGGCDGTHPHLSLSFPYGQLTFGFKQDLHQSPSTVYLDYMAVEYNVSFPQAAQWTFMAQNSSLRELQAPLGQSFCCGNASIVLSPAVHLDLLSLRLQAAQLPDKGHFGPCFSCNRDQS
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Tris-based buffer,50% glycerol
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
  • 基因功能參考文獻:
    1. Findings indicate that human CD68 and its mouse ortholog macrosialin located in the lysosomal membrane and share many structural similarities. PMID: 27869795
    2. Myeloid osteoclast precursors do not express CD68. PMID: 28173622
    3. CD68, a putative receptor for sporozoite invasion of Kupffer cells that acts as a gateway for malaria infection of the liver. PMID: 26216124
    4. Results showed that activated microglia in Alzheimer's disease-like mice showed two-step transition: a CD68-negative activated form at 6-9 months and a CD68-positive form from 12 months of age PMID: 25352454
    5. Statins promote the beneficial remodeling of plaques in diseased mouse arteries through the stimulation of the CCR7 / CD68 emigration pathway in macrophages PMID: 22163030
    6. These findings demonstrate a role for CD68 in the function of osteoclasts. PMID: 21991369
    7. CD68-null mononuclear phagocytes exhibited a trend toward enhanced antigen presentation to CD4+ T cells, indicating that CD68 may function to negatively regulate antigen uptake, loading, or major histocompatibility complex class II trafficking. PMID: 21572087
    8. Atherogenic diet-induced reduction in lipid levels of Reversa model mouse leads to decreased monocyte-derived CD68-positive cells in advanced atherosclerotic plaques and is associated with emigration of these cells from the atherosclerotic plaques. PMID: 21339485
    9. Macrosialin does not function as an oxLDL receptor on the cell surface. PMID: 12562841
    10. Data show that macrosialin (CD68), a macrophage-specific protein, is increased by aging in selected brain regions of male C57BL/6NNia mice. PMID: 16157452

    顯示更多

    收起更多

  • 亞細胞定位:
    [Isoform Long]: Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein.; [Isoform Short]: Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    LAMP family
  • 組織特異性:
    Expressed in tissue macrophages and to a lesser extent in dendritic cells.
  • 數據庫鏈接:


主站蜘蛛池模板: 亚洲人成网站在线观看69影院 | 国内精品久久久久影视| 99精品国产兔费观看久久| 国产av久久人人澡人人爱| 国产精品鲁鲁鲁| 成人亚洲精品777777| 免费少妇荡乳情欲视频| 欧美怡红院免费全部视频| 亚洲欧美日韩综合一区| 久久精品人妻一区二区三区| 全球成人中文在线| 亚洲精品久久久久一区二区三区 | 夜夜天天噜狠狠爱2019| 免费国精产品wnw2544| 大香伊蕉在人线国产免费| 欧美韩中文精品有码视频在线| 亚洲国产欧美在线成人app| 就去干成人网| 少妇饥渴xxhd麻豆xxhd骆驼| 国产成人综合色在线观看网站| 亚洲精品国产情侣av在线| 日本高清二区视频久二区| 国产成人一区二区不卡免费视频| 中出内射颜射骚妇| 真实国产乱子伦对白视频不卡 | 三上悠亚精品一区二区久久| 国产成人精品一区二区不卡| 亚洲欧美日韩国产国产a| 三级特黄60分钟在线播放| 欧美成人aaa片一区国产精品| 欧美日韩精品无码一本二本三本色| 天堂网在线www资源| 国产人妻精品午夜福利免费| 99精品国产在热久久| 久久婷婷六月综合色液啪| 亚洲 欧洲 日韩 综合av| 久久久无码一区二区三区| 2022久久国产精品免费热麻豆| 国产成人精品a∨一区二区| 无码午夜人妻一区二区三区不卡视频| 精品久久久久久无码中文野结衣|