在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Transforming growth factor beta activator LRRC33 (NRROS), partial

Recombinant Mouse Transforming growth factor beta activator LRRC33 (NRROS), partial

  • 中文名稱：
    小鼠Nrros重組蛋白
  • 貨號：
    CSB-YP807383MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Nrros重組蛋白
  • 貨號：
    CSB-EP807383MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Nrros重組蛋白
  • 貨號：
    CSB-BP807383MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Nrros重組蛋白
  • 貨號：
    CSB-MP807383MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Nrros
  • Uniprot No.：
  • 別名：
    Nrros; Lrrc33Transforming growth factor beta activator LRRC33; Leucine-rich repeat-containing protein 33; Negative regulator of reactive oxygen species
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Key regulator of transforming growth factor beta-1 (TGFB1) specifically required for microglia function in the nervous system. Required for activation of latent TGF-beta-1 in macrophages and microglia: associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGFB1, and regulates integrin-dependent activation of TGF-beta-1. TGF-beta-1 activation mediated by LRRC33/NRROS is highly localized: there is little spreading of TGF-beta-1 activated from one microglial cell to neighboring microglia, suggesting the existence of localized and selective activation of TGF-beta-1 by LRRC33/NRROS. Indirectly plays a role in Toll-like receptor (TLR) signaling: ability to inhibit TLR-mediated NF-kappa-B activation and cytokine production is probably a consequence of its role in TGF-beta-1 signaling (Probable).
  • 基因功能參考文獻：
    1. NRROS-deficient (Nrros(-/-)) mice show defects in motor functions and die before 6 months of age. Nrros(-/-) mice display astrogliosis and lack normal CD11b(hi)CD45(lo) microglia, but they show no detectable demyelination or neuronal loss. perivascular macrophage-like myeloid cells populate the Nrros(-/-) CNS. Cx3cr1-driven deletion of Nrros shows its crucial role in microglial establishment during early embryonic stages. PMID: 28459434
    2. this study presents NRROS as a novel negative regulator of RANKL-induced osteoclastogenesis. PMID: 26442864
    3. results suggest that LRRC33 and TLRs may form a negative-feedback loop, which is important for the maintenance of immune homeostasis. PMID: 24550525
    4. NRROS provides a hitherto undefined mechanism for regulating ROS production--one that enables phagocytes to produce higher amounts of ROS, if required to control invading pathogens, while minimizing unwanted collateral tissue damage PMID: 24739962
  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.
  • 組織特異性：
    Mainly expressed in cells of hematopoietic origin, such as in immune organs such as lymph nodes, thymus and spleen. Among leukocytes, expressed at higher level in myeloid cell such as macrophages, neutrophils and dendritic cells. Highly expressed in centr
  • 數據庫鏈接：


主站蜘蛛池模板： 最近日本免费观看高清视频 | 国产精品色情国产三级在| av免费播放一区二区三区| 2021亚洲国产成a在线| 国产美女精品视频线免费播放| 后入内射国产一区二区| 99久久久无码国产精品免费 | 欧美真人性野外做爰| 高大丰满欧美熟妇hd| 精品欧美成人高清在线观看| 性xxxx18免费观看视频| 久久久久亚洲精品男人的天堂| 国产有奶水哺乳期无码avav| 国产成人亚洲综合无码品善网| 在线观看特色大片免费视频| 久久精品一区二区三区av| 亚洲熟妇无码av另类vr影视| 亚洲最大无码av网站观看| 伊人久久大香线蕉av五月天宝贝| 国产精品情侣呻吟对白视频| 婷婷丁香五月六月综合激情啪| 亚洲一区二区三区在线网址| 人妻少妇中文字幕乱码 | 国产成人精品一区二区三区视频 | 欧美 亚洲 日韩 中文2019| 久久国产中文娱乐网| 天天做天天爱天天综合网| 无码国产成人午夜电影观看| 亚洲精品无码ma在线观看| 加勒比久久综合网天天| 丰满大爆乳波霸奶| 末成年毛片在线播放| 午夜成人理论无码电影在线播放 | 日本国产成人国产在线播放| 四虎成人精品永久网站| 麻豆av福利av久久av| 国产xxxx69真实实拍| 久久精品免费一区二区三区| 日韩人妻无码一区二区三区| 一二三四视频社区在线播放中国| 在线无码av一区二区三区|