在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Transcription factor HES-7 (Hes7)

Recombinant Mouse Transcription factor HES-7 (Hes7)

  • 中文名稱：
    小鼠Hes7重組蛋白
  • 貨號(hào)：
    CSB-YP806395MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Hes7重組蛋白
  • 貨號(hào)：
    CSB-EP806395MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Hes7重組蛋白
  • 貨號(hào)：
    CSB-EP806395MO-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Hes7重組蛋白
  • 貨號(hào)：
    CSB-BP806395MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Hes7重組蛋白
  • 貨號(hào)：
    CSB-MP806395MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Hes7
  • Uniprot No.：
  • 別名：
    Hes7; Transcription factor HES-7; mHes7; Hairy and enhancer of split 7; bHLH factor Hes7
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-225
  • 氨基酸序列
    MVTRERAENR DGPKMLKPLV EKRRRDRINR SLEELRLLLL ERTRDQNLRN PKLEKAEILE FAVGYLRERS RVEPPGVPRS PGQDAEALAS CYLSGFRECL LRLAAFAHDA SPAARSQLFS ALHGYRRPKP PRPEAVDPGL PAPRPPLDPA SPILGPALHQ RPPVHQGPPS PRLAWSPSHC SSRAGDSGAP APLTGLLPPP PPPYRQDGAP KAPSLPPPAF WRPWP
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM). May function as a segmentation clock, which is essential for coordinated somite segmentation.
  • 基因功能參考文獻(xiàn)：
    1. Hes7 oscillation is synchronized between neighboring cells, and the posterior-anterior axis is self-organized as the central-peripheral axis PMID: 29437832
    2. Lengthening the third Hes7 intron by 10 or 20 kb disrupts accurate RNA splicing and inactivates the gene. PMID: 22326607
    3. Fgf signaling was found to be a primary target for hypoxia, which causes phenotypic variations of heterozygous mutations in Hes7 or Mesp2, suggesting gene-environment interaction through this signaling. PMID: 23465881
    4. Hes7 is a key regulator of the pace of the segmentation clock. PMID: 23219549
    5. Tbx6 and the Wnt pathway cooperatively regulate proper Hes7 expression. PMID: 23326414
    6. introns lead to an approximately 19-min delay in the Hes7 gene expression, and mathematical modeling suggested that without such a delay, Hes7 oscillations would be abolished PMID: 21300886
    7. there are differential axial requirements for lunatic fringe and Hes7 transcription during mouse somitogenesis PMID: 19956724
    8. periodic repression by Hes7 protein is critical for the cyclic transcription of Hes7 and Lfng, and this negative feedback represents a molecular basis for the segmentation clock PMID: 12783854
    9. instability of Hes7 is essential for sustained oscillation and for its function as a segmentation clock PMID: 15170214
    10. Lunatic fringe and Hes7 controls their oscillatory expression during somitogenesis by forming negative feedback loop PMID: 16342160
    11. Hes7 oscillation is initiated by Fgf signaling and propagated/maintained anteriorly by Notch signaling. PMID: 17681139
    12. repressor functionality and the half-life of the protein is crucial for oscillatory expression of Hes7 and regular somite formation PMID: 17983837
    13. These results indicate that common amino acid residues are involved in both the transcriptional repressor activity and the instability of Hes7 protein, suggesting of a critical link between the transcription and degradation control. PMID: 18477475
    14. Sprouty4 does not oscillate in Hes7-null mutant mouse embryos, and Hes7 can inhibit FGF-induced transcriptional activity of the Sprouty4 promoter. PMID: 19440349

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus.
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 亚洲第一a在线观看网站| 无码精品人妻一区二区三区av| 一本色道久久99一综合| 女人夜夜春精品a片| 中文字幕人妻无码视频| 可以看三级的网站| 久久亚洲精品国产精品777777| 久久天堂av综合合色蜜桃网| 免费毛片在线看片免费丝瓜视频 | 男女做爰无遮挡性视频| 国产凹凸在线一区二区| 狠狠狠狼鲁亚洲综合网| 粉嫩粉嫩的18在线观看| 一区二区三区鲁丝不卡麻豆| 国产成人亚洲精品无码青青草原| 亚洲肥老太bbw中国熟女| 国产精品99无码一区二区| 日本精品久久久久中文字幕| 亚洲综合av一区二区三区不卡| 奇米影视7777狠狠狠狠影视| 一本大道无码人妻精品专区| 成人性生交大片免费看| 任你干视频精品播放| 午夜免费啪在线观看视频| 日韩精品一区二区三区色欲av| 永久免费看mv网站入口亚洲| 国产精品99久久精品| 精品成人a区在线观看| 欧美另类精品xxxx| 久久99精品久久久久久水蜜桃| 国产探花在线精品一区二区| 日本熟妇人妻xxxxx-欢迎您| 亚洲中文字幕aⅴ天堂| 国产午夜亚洲精品不卡在线观看 | 日韩人妻无码一区二区三区综合部| 亚洲中文字幕码在线电影| 在线 国产 精品 蜜芽| 永久免费不卡在线观看黄网站| 好爽毛片一区二区三区四| 99精品产国品一二三产区| 四虎成人精品永久在线视频 |