在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Spectrin beta chain, non-erythrocytic 1 (Sptbn1), partial

In Stock
  • 中文名稱:
    小鼠Sptbn1重組蛋白
  • 貨號:
    CSB-YP733819MO
  • 規格:
    ¥2616
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 95% as determined by SDS-PAGE.
  • 生物活性:
    Not Test
  • 基因名:
    Sptbn1
  • Uniprot No.:
  • 別名:
    Beta-II spectrin;Embryonic liver fodrin;Fodrin beta chain
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Partial
  • 來源:
    Yeast
  • 分子量:
    13.8 kDa
  • 表達區域:
    2199-2304aa
  • 氨基酸序列
    MEGFLNRKHEWEAHNKKASSRSWHNVYCVINNQEMGFYKDAKSAASGIPYHSEVPVSLKEAICEVALDYKKKKHVFKLRLSDGNEYLFQAKDDEEMNTWIQAISSA
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    C-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
  • 基因功能參考文獻:
    1. required for proper development of the heart PMID: 24064296
    2. The findings showed that beta-2 spectrin plays a crucial role in hepatocyte proliferation, which contributes to liver regeneration. PI3K/Akt was involved in TGFbeta/Smad signalling pathway through the interaction with Smad proteins and beta-2 spectrin. PMID: 22541060
    3. These data reveal that embryonic liver fodrin is involved in hepatic stellate cell activation and the formation of regenerative nodules derived from hepatic progenitor cells in cirrhotic liver. PMID: 21388516
    4. costamere-association of dynactin-4 did not require dystrophin but did depend on beta2 spectrin and ankyrin-B, whereas costamere association of ankyrin-B required beta2 spectrin PMID: 21186323
    5. ELF is involved in the pathogenesis of primary biliary cirrhosis and hepatocellular carcinoma. PMID: 15566516
    6. Data show that Spnb2 [beta2SP(+/-)] mice are born with many phenotypic characteristics observed in BWS patients, suggesting that beta2SP mutant mice phenocopy BWS, and beta2SP loss could be one of the mechanisms associated with BWS. PMID: 20739274
    7. downregulated expression in T cells following treatment with bis(tri-n-butylin)oxide (TBTO), an immunotoxic organotin PMID: 19552622
    8. results point to ELF as an essential adaptor protein required for key events in the propagation of TGF-beta signaling PMID: 12543979
    9. interaction between members of the ankyrin and beta-spectrin families previously established in erythrocytes and axon initial segments also occurs in neonatal cardiomyocytes with ankyrin-B and beta(2)-spectrin. PMID: 15262991
    10. In response to ELF deficiency, the abnormalities of G1/S checkpoint and senescence contribute their increment of susceptibility to malignant transformation. PMID: 16650383
    11. E-cadherin thus requires both ankyrin-G and beta-2-spectrin for its cellular localization in early embryos as well as cultured epithelial cells. PMID: 17620337
    12. ELF, a TGF-beta adaptor and signaling molecule, functions as a critical adaptor protein in TGF-beta modulation of angiogenesis as well as cell cycle progression. PMID: 18704924

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, cytoskeleton. Endomembrane system. Cytoplasm, myofibril, sarcomere, M line.; [Isoform 2]: Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族:
    Spectrin family
  • 組織特異性:
    Isoform 2 is present in brain, heart, kidney and liver (at protein level).
  • 數據庫鏈接:


主站蜘蛛池模板: 亚洲这里只有久热精品伊人| 无码日韩人妻精品久久蜜桃| 玩弄japan白嫩少妇hd| 综合久久国产九一剧情麻豆| 人人澡人人澡人人看添av| 亚洲va在线∨a天堂va欧美va| 少妇人妻邻居| 色喜国模李晴超大尺度| 日本成本人三级在线观看| 国产免费踩踏调教视频| 艳妇乳肉豪妇荡乳av| 少妇被粗大的猛烈进出图片| 火箭视频在线观看精品| 欧美成人天天综合在线| 影音先锋每日av色资源站| 国产剧情国产精品一区| 国产无套护士在线观看| 男女啪啦啦超猛烈动态图| 1000部拍拍拍18勿入免费视频下载 | 色妞精品av一区二区三区| 国产xxx视频在线观看软件| 亚洲综合久久一本久道| 久久精品中文字幕| 在线精品动漫一区二区无码| 最近最好的中文字幕2019免费| 免费精品99久久国产综合精品| 国产丰满老熟女重口对白| 免费无遮挡很爽很污很黄的网站| 一本热久久sm色国产| 天堂а√中文在线官网| 亚洲精品卡2卡三卡4卡2卡乱码 | 7777精品伊久久久大香线蕉| 69国产精品成人aaaaa片| 欧美另类高清zo欧美| 国产乱人伦偷精品视频免下载| 午夜男女无遮挡拍拍视频| 经典三级欧美在线播放| 性色av无码一区二区三区人妻 | 久久精品伊人久久精品伊人| 亚洲欧美日韩精品久久| 亚洲中文字幕无码mv|