在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Spectrin beta chain, non-erythrocytic 1 (Sptbn1), patial

  • 中文名稱:
    小鼠Sptbn1重組蛋白
  • 貨號:
    CSB-MP733819MO
  • 規格:
    ¥1140
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
    • The purity of Sptbn1 was greater than 95% as determined by SEC-HPLC
  • 其他:

產品詳情

  • 純度:
    Greater than 95% as determined by SDS-PAGE.
    Greater than 95% as determined by SEC-HPLC.
  • 生物活性:
    Not Test
  • 基因名:
    Sptbn1
  • Uniprot No.:
  • 別名:
    Beta-II spectrin;Embryonic liver fodrin;Fodrin beta chain
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Partial
  • 來源:
    Mammalian cell
  • 分子量:
    41.2 kDa
  • 表達區域:
    2199-2304aa
  • 氨基酸序列
    MEGFLNRKHEWEAHNKKASSRSWHNVYCVINNQEMGFYKDAKSAASGIPYHSEVPVSLKEAICEVALDYKKKKHVFKLRLSDGNEYLFQAKDDEEMNTWIQAISSA
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    C-terminal hFc1-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
  • 基因功能參考文獻:
    1. required for proper development of the heart PMID: 24064296
    2. The findings showed that beta-2 spectrin plays a crucial role in hepatocyte proliferation, which contributes to liver regeneration. PI3K/Akt was involved in TGFbeta/Smad signalling pathway through the interaction with Smad proteins and beta-2 spectrin. PMID: 22541060
    3. These data reveal that embryonic liver fodrin is involved in hepatic stellate cell activation and the formation of regenerative nodules derived from hepatic progenitor cells in cirrhotic liver. PMID: 21388516
    4. costamere-association of dynactin-4 did not require dystrophin but did depend on beta2 spectrin and ankyrin-B, whereas costamere association of ankyrin-B required beta2 spectrin PMID: 21186323
    5. ELF is involved in the pathogenesis of primary biliary cirrhosis and hepatocellular carcinoma. PMID: 15566516
    6. Data show that Spnb2 [beta2SP(+/-)] mice are born with many phenotypic characteristics observed in BWS patients, suggesting that beta2SP mutant mice phenocopy BWS, and beta2SP loss could be one of the mechanisms associated with BWS. PMID: 20739274
    7. downregulated expression in T cells following treatment with bis(tri-n-butylin)oxide (TBTO), an immunotoxic organotin PMID: 19552622
    8. results point to ELF as an essential adaptor protein required for key events in the propagation of TGF-beta signaling PMID: 12543979
    9. interaction between members of the ankyrin and beta-spectrin families previously established in erythrocytes and axon initial segments also occurs in neonatal cardiomyocytes with ankyrin-B and beta(2)-spectrin. PMID: 15262991
    10. In response to ELF deficiency, the abnormalities of G1/S checkpoint and senescence contribute their increment of susceptibility to malignant transformation. PMID: 16650383
    11. E-cadherin thus requires both ankyrin-G and beta-2-spectrin for its cellular localization in early embryos as well as cultured epithelial cells. PMID: 17620337
    12. ELF, a TGF-beta adaptor and signaling molecule, functions as a critical adaptor protein in TGF-beta modulation of angiogenesis as well as cell cycle progression. PMID: 18704924

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, cytoskeleton. Endomembrane system. Cytoplasm, myofibril, sarcomere, M line.; [Isoform 2]: Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族:
    Spectrin family
  • 組織特異性:
    Isoform 2 is present in brain, heart, kidney and liver (at protein level).
  • 數據庫鏈接:


主站蜘蛛池模板: 狼色精品人妻在线视频| 国产精品一国产精品一k频道| 久久久亚洲欧洲日产国码二区| 成人午夜亚洲精品无码区| 国产午夜福利久久精品| 久久午夜夜伦鲁鲁片免费无码| 亚洲日韩成人性av网站| 精品国产乱码久久久久乱码| 国产99视频精品免费观看9| 亚洲爆乳少妇无码激情| 国产成人一区二区三区别 | 性色av蜜臀av色欲av| 日本无翼乌邪恶大全彩h| 色综合网天天综合色中文| 久久理论片午夜琪琪电影院| 99久久国产综合精品成人影院| 国产精品久久久久久久| 亚洲一二三四2021不卡| 无码午夜福利视频1000集| 怡红院av亚洲一区二区三区h| 99精品无人区乱码在线观看| 亚洲区欧美区综合区自拍区| 久久人人爽人人爽爽久久小说 | 无码一区二区三区视频| 中文字幕在线亚洲精品| 亚洲国产成人精品福利| 日本少妇寂寞少妇aaa| 国产午夜亚洲精品国产成人小说 | 暖暖 在线 日本 免费 中文| 99国产在线精品视频| 黑色丝袜无码中中文字幕| 国产精品欧美亚洲韩国日本久久| 亚洲乱码国产乱码精品精大量| 欧美日韩在手机线旡码可下载| 日日av拍夜夜添久久免费| 偷拍区清纯另类丝袜美腿| 日产乱码一区二区三区在线| 亚洲精品图片区小说区| 女人扒开屁股桶爽30分钟| 777精品出轨人妻国产| 亚洲精品tv久久久久久久久j |