在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Guanylate cyclase activator 2B (Guca2b)

In Stock
  • 中文名稱:
    小鼠Guca2b重組蛋白
  • 貨號:
    CSB-YP010048MO
  • 規格:
    ¥2208
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    Guca2b
  • Uniprot No.:
  • 別名:
    Guca2b; Guanylate cyclase activator 2B [Cleaved into: Uroguanylin; UGN)]
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    Yeast
  • 分子量:
    11.4kDa
  • 表達區域:
    22-106aa
  • 氨基酸序列
    VYIKYHGFQVQLESVKKLNELEEKEMSNPQPRRSGLLPAVCHNPALPLDLQPVCASQEAASTFKALRTIATDECELCINVACTGC
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport.
  • 基因功能參考文獻:
    1. In obese mice UGN expression was decreased, whereas leptin treatment up-regulated UGN levels in duodenum in these genetically modified mice compared to WT. PMID: 25743370
    2. UGN exerts its inhibitory activity on the prendrin gene promoter likely via heat shock factor 1 action at a defined heat shock element site. PMID: 22129966
    3. findings establish a role for uroguanylin in an enteric-renal communication axis as well as a fundamental principle of this axis in the maintenance of salt homeostasis in vivo PMID: 14561709
    4. act on the mouse kidney, in part, through a cGMP-dependent, GC-C-independent mechanism, causing significant natriuresis by renal tubular processes. PMID: 14675035
    5. Role for uroguanylin in fluid homeostasis and as an integral component of a signaling mechanism that mediates changes in Na excretion in response to an enteral salt loading. PMID: 16819406

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Guanylin family
  • 組織特異性:
    Localized predominantly in intestinal villi and the corticomedullary junction of the kidney.
  • 數據庫鏈接:

    KEGG: mmu:14916

    STRING: 10090.ENSMUSP00000043203

    UniGene: Mm.278



主站蜘蛛池模板: 国产香蕉尹人在线视频你懂的| 成人区人妻精品一区二区三区| 一本一本久久aa综合精品| 国产成人精品福利网站| 中文字幕人妻中文av不卡专区| 无码国产精品一区二区免费式芒果| 在线看片免费人成视频福利| 亚洲人成无码网www电影榴莲| 无码制服丝袜人妻在线视频精品 | 日本中文一区二区三区亚洲| 色偷偷色噜噜狠狠网站久久| 精品少妇人妻av免费久久久| 亚洲熟妇无码av另类vr影视| 中文字幕+乱码+中文乱码www| 亚洲v欧美v日韩v国产v| 亚洲成a v人片在线观看| 桃花色综合影院| 欧美成人看片一区二区| 日韩欧美tⅴ一中文字暮| 精品一区二区三区在线播放视频| 精品久久香蕉国产线看观看亚洲| 偷拍区清纯另类丝袜美腿| 亚洲精品熟女国产| 国产精品国产av片国产| 日韩免费无码成人久久久久久片| 青草青草视频2免费观看| 99re热这里只有精品视频| 爱色精品视频一区二区| 精品国产午夜福利精品推荐| 邻居少妇张开腿让我爽了在线观看| 国产在线拍偷自揄拍无码| 国产成人亚洲日韩欧美| 国产在线精品一区在线观看| 亚洲人成影院在线观看| 午夜精品久久久久久久久| 最新网站亚洲人成无码| 男人把女人桶到爽免费应用| 玩弄japan白嫩少妇hd小说| 国产熟女亚洲精品麻豆| 国产在线无码视频一区二区三区| 狠狠色色综合网站|