在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Glutathione S-transferase P 1 (Gstp1)

Recombinant Mouse Glutathione S-transferase P 1 (Gstp1)

  • 中文名稱：
    小鼠Gstp1重組蛋白
  • 貨號：
    CSB-BP009989MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Gstp1重組蛋白
  • 貨號：
    CSB-EP009989MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Gstp1重組蛋白
  • 貨號：
    CSB-MP009989MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    Greater than 85% as determined by SDS-PAGE.
  • 基因名：
  • Uniprot No.：
  • 別名：
    Gstp1; GstpibGlutathione S-transferase P 1; Gst P1; EC 2.5.1.18; GST YF-YF; GST class-pi; GST-piB; Preadipocyte growth factor
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-210aa
  • 氨基酸序列
    PPYTIVYFPVRGRCEAMRMLLADQGQSWKEEVVTIDTWMQGLLKPTCLYGQLPKFEDGDLTLYQSNAILRHLGRSLGLYGKNQREAAQMDMVNDGVEDLRGKYVTLIYTNYENGKNDYVKALPGHLKPFETLLSQNQGGKAFIVGDQISFADYNLLDLLLIHQVLAPGCLDNFPLLSAYVARLSARPKIKAFLSSPEHVNRPINGNGKQ
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.
  • 基因功能參考文獻：
    1. Expression of both wild-type and catalytically-inactive Y7F mutant GSTP significantly attenuated LPS- or IKKbeta-induced production of GM-CSF. These studies indicate a complex role for GSTP in modulating NF-kappaB, which may involve S-glutathionylation of IKK proteins, and interaction with NF-kappaB family members. PMID: 27058114
    2. GSTP can exert redox regulation in the oxidative ER environment and indicate that, within the ER, GSTP influences the cellular consequences of the UPR through S-glutathionylation of a series of key interrelated proteins. Antioxid. PMID: 26838680
    3. our study reveals the novel role of GSTP1 in regulation of iNOS by affecting S-nitrosylation, dimerization, and stability. PMID: 26361746
    4. These observed differences contribute to our understanding of how genetic ablation of GSTP causes different levels of myeloproliferation and migration [corrected] PMID: 25216273
    5. GSTP1 expression in retina increases with developmental age in mice and accompanies murine retinal maturation. PMID: 24664677
    6. GSTP knock-out mice display decreased ubiquitination capacity and overall increased susceptibility to oxidative stress. PMID: 23129554
    7. Report increased GSTP1 in airways of asthmatic mice. PMID: 23647087
    8. DNIC storage function of GST P1-1 and ability of MRP1 to efflux DNICs are vital in protection against NO cytotoxicity PMID: 22084240
    9. Gst-pi expression of the prostate cancers are dependent on metastatic site. PMID: 21748757
    10. GSTP plays a major role in carcinogenesis distinct from its role in detoxification and provides evidence that the enzyme is a key determinant of the proinflammatory tumor environment. PMID: 21975931
    11. This study analysed the kinetic behaviour of all the various cysteine to alanine mutants of Gstp1. These mutations introduce cooperativity and a novel 'ping pong' mechanism in the case of the C169A mutant. PMID: 21134126
    12. Sequential catalysis of Aldr1 by glutathione S-transferase P and glutaredoxin may be a general redox switching mechanism that regulates the reduction of protein sulfenic acids to cysteines regulates the reduction of protein sulfenic acids to cysteines PMID: 20538586
    13. role in activating Pi-class glutathione S-transferase gene in conjunction with androgens PMID: 12023900
    14. Differential expression of GSTpi contributes to the sensitivity to xenobiotics in the substantia nigra and may influence the pathogenesis of reactive oxygen species-induced neurological disorders including Parkinson's disease. PMID: 17267597
    15. GSTP1 attenuates the severity of allergic airways disease. However, the efficacy of GSTP1 correlated with mouse strain-dependent variation in Gstp1 expression. PMID: 18787219
    16. Results suggest that GSTpi expression may be part of the mechanism underlying the ability of glial cells to elicit protection against the mechanisms involved in MPTP-induced neuronal death. PMID: 18792812
    17. GSTP1 prevented LPS-induced TNF-alpha, IL-1beta, MCP-1 and NO production. PMID: 18962899
    18. Catalysis of S-glutathionylation at low pK cysteines in proteins is a novel property for GSTpi PMID: 18990698

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Mitochondrion. Nucleus.
  • 蛋白家族：
    GST superfamily, Pi family
  • 組織特異性：
    Ubiquitously expressed.
  • 數據庫鏈接：


主站蜘蛛池模板： 图片区 小说区 区 亚洲五月| 成人艳情一二三区| 成在线人永久免费视频播放| 国产综合久久久久| 国产精品亚洲成在人线| 伊人精品一本久久综合| 国产美女视频免费观看的网站| 辽宁熟女高潮狂叫视频| 巨大乳女人做爰视频在线看| 日本乱码伦午夜福利在线| 国产精品99精品久久免费 | 人妻少妇精品中文字幕av| 性大毛片视频| 呻吟国产av久久一区二区| 性色av无码专区一ⅴa亚洲| 精品国产午夜福利精品推荐| 国产精品久久久久久久久久直播| 中文无码乱人伦中文视频在线v | 大肉大捧一进一出好爽动态图| 国产在线高清理伦片a| 国精产品48x国精产品| 中文字幕被公侵犯的漂亮人妻 | 精品蜜臀久久久久99网站| 国产一区二区三区乱码在线观看| 好紧好爽好湿别拔出来视频男男| 久久综合九色综合欧美婷婷| 国内高清a自拍视频| 日韩a片无码毛片免费看| 久久精品中文字幕| 久久伊人精品波多野结衣| 亚洲精品成人网线在线播放va| 2021精品国产自在现线看| 男女下面进入的视频免费午夜| 一区二区国产精品精华液| 欲求不满邻居的爆乳在线播放| 女高中生第一次破苞av| 国产精品玩偶在线观看| 欧美成人片在线观看| 免费又黄又裸乳的视频| 秋霞国产精品一区二区| 无套内射在线观看theporn|