在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Gamma-synuclein (Sncg)

In Stock
  • 中文名稱:
    小鼠Sncg重組蛋白
  • 貨號:
    CSB-EP5197MO
  • 規格:
    ¥1836
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 生物活性:
    Not Test
  • 基因名:
    Sncg
  • Uniprot No.:
  • 別名:
    Persyn
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full Length
  • 來源:
    E.coli
  • 分子量:
    20.2 kDa
  • 表達區域:
    1-123aa
  • 氨基酸序列
    MDVFKKGFSIAKEGVVGAVEKTKQGVTEAAEKTKEGVMYVGTKTKENVVQSVTSVAEKTKEQANAVSEAVVSSVNTVANKTVEEAENIVVTTGVVRKEDLEPPAQDQEAKEQEENEEAKSGED
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    C-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases. May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway.
  • 基因功能參考文獻:
    1. results indicate that gamma-synuclein is capable of binding to synaptic vesicles, but the mechanism of its interaction with these structures is fundamentally different from the mechanism proposed for alpha-synuclein PMID: 24993968
    2. The results of this study suggested that gamma-synuclein is directly involved in the regulation of cognitive functions. PMID: 23672583
    3. gamma-Synuclein binds synaptic vesicles but is unable to rescue the phenotype of CSPalpha-deficient mice. PMID: 23129765
    4. gamma-synuclein is a regulator of lipid handling in adipocytes, the function of which is particularly important in conditions of nutrient excess PMID: 23213245
    5. Synuclein-alpha, -beta, and -gamma are important in regulating neurotransmitter release from specific populations of midbrain dopamine neurons through mechanisms that differ from those reported in other neurons. PMID: 21593311
    6. The loss of gamma-synuclein results in a significant increase in the level of orientation response in novel environment and decrease in the level of state anxiety. PMID: 21469331
    7. gamma-Synuclein is necessary for the increased Mac-2 expression by myelination-transition-zone astrocytes during glaucoma. PMID: 21199938
    8. The effects of gamma-synuclein deficiency on motor and peripheral sensory neurons were studied. Gamma-synuclein is dispensable for the development and function of the nervous system. PMID: 14585981
    9. Immunohistochemistry demonstrates accelerated accumulation of gamma-synuclein in gracile axonal dystrophy mice. Gamma-synuclein appears in the gracile nucleus at 3 weeks of age and was maintained until 32 weeks. PMID: 15306232
    10. These data indicate the chaperone activity of SNCG on stimulation of steroid receptor signaling in mammary gland. PMID: 17016445
    11. Groups of genes that were similarly altered in SNCA deficient and SNCG deficient mice, leading to nerve degeneration. PMID: 17318638
    12. Together, our data suggest an early role for SYN and inflammation in PD pathogenesis. PMID: 17537546
    13. loss of both alpha- and gamma-synuclein causes an increase in release probability from dopaminergic synapses PMID: 18333965
    14. Mice expressing high levels of gamma-synuclein develop severe and fatal neurological disease. PMID: 19246516

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle.
  • 蛋白家族:
    Synuclein family
  • 組織特異性:
    Highly expressed in brain, particularly in the substantia nigra. Also expressed in the corpus callosum, heart, skeletal muscle, ovary, testis, colon and spleen. Weak expression in pancreas, kidney and lung. Expressed predominantly in the cell bodies and a
  • 數據庫鏈接:


主站蜘蛛池模板: 久久www成人_看片免费不卡| 亚洲精品一区久久久久一品av| 99精品国产在热久久婷婷| 国产亚洲精品久久久久久小舞| 亚洲成av人片在一线观看| 亚洲精品无码专区在线观看| 草草网站影院白丝内射| 中文字幕人妻熟女人妻| 亚洲一区二区三区香蕉| 色欲天天网站欧美成人福利网| 韩国国内大量揄拍精品视频| 精品亚洲国产成人av在线小说| 亚洲成a∨人片在线观看不卡| 国产私拍大尺度在线视频| 久久青青草原国产精品最新片| 欧美另类精品xxxx人妖| 精品国产av 无码一区二区三区 | 中文字幕av无码不卡免费| 亚洲aⅴ天堂av天堂无码| 中文无码伦av中文字幕| 少妇被猛男粗大的猛进出| 综合图区亚洲另类偷窥| 欧美影视精品久久| 精品人无码一区二区三区| 亚洲欧洲免费无码| 天天拍夜夜添久久精品| 欧美不卡视频一区发布| 宅男噜噜噜66网站在线观看| 亚洲爆乳无码一区二区三区| 中文天堂在线资源www| 亚洲卡一卡二乱码新区仙踪| 日韩国产成人无码av毛片| 插鸡网站在线播放免费观看| 18禁止观看强奷免费国产大片| 日本人与黑人做爰视频网站| 免费ā片在线观看| 99热门精品一区二区三区无码| 草草网站影院白丝内射| 东京热无码av一区二区| 国产成人精品成人a在线观看| 日韩人妻不卡一区二区三区|