在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Gamma-synuclein(Sncg)

In Stock
  • 中文名稱:
    小鼠Sncg重組蛋白
  • 貨號:
    CSB-EP5197MOb1
  • 規格:
    ¥1836
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 生物活性:
    Not Test
  • 基因名:
    Sncg
  • Uniprot No.:
  • 別名:
    Persyn
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full Length
  • 來源:
    E.coli
  • 分子量:
    18.3 kDa
  • 表達區域:
    1-123aa
  • 氨基酸序列
    MDVFKKGFSIAKEGVVGAVEKTKQGVTEAAEKTKEGVMYVGTKTKENVVQSVTSVAEKTKEQANAVSEAVVSSVNTVANKTVEEAENIVVTTGVVRKEDLEPPAQDQEAKEQEENEEAKSGED
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged and C-terminal Myc-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases. May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway.
  • 基因功能參考文獻:
    1. results indicate that gamma-synuclein is capable of binding to synaptic vesicles, but the mechanism of its interaction with these structures is fundamentally different from the mechanism proposed for alpha-synuclein PMID: 24993968
    2. The results of this study suggested that gamma-synuclein is directly involved in the regulation of cognitive functions. PMID: 23672583
    3. gamma-Synuclein binds synaptic vesicles but is unable to rescue the phenotype of CSPalpha-deficient mice. PMID: 23129765
    4. gamma-synuclein is a regulator of lipid handling in adipocytes, the function of which is particularly important in conditions of nutrient excess PMID: 23213245
    5. Synuclein-alpha, -beta, and -gamma are important in regulating neurotransmitter release from specific populations of midbrain dopamine neurons through mechanisms that differ from those reported in other neurons. PMID: 21593311
    6. The loss of gamma-synuclein results in a significant increase in the level of orientation response in novel environment and decrease in the level of state anxiety. PMID: 21469331
    7. gamma-Synuclein is necessary for the increased Mac-2 expression by myelination-transition-zone astrocytes during glaucoma. PMID: 21199938
    8. The effects of gamma-synuclein deficiency on motor and peripheral sensory neurons were studied. Gamma-synuclein is dispensable for the development and function of the nervous system. PMID: 14585981
    9. Immunohistochemistry demonstrates accelerated accumulation of gamma-synuclein in gracile axonal dystrophy mice. Gamma-synuclein appears in the gracile nucleus at 3 weeks of age and was maintained until 32 weeks. PMID: 15306232
    10. These data indicate the chaperone activity of SNCG on stimulation of steroid receptor signaling in mammary gland. PMID: 17016445
    11. Groups of genes that were similarly altered in SNCA deficient and SNCG deficient mice, leading to nerve degeneration. PMID: 17318638
    12. Together, our data suggest an early role for SYN and inflammation in PD pathogenesis. PMID: 17537546
    13. loss of both alpha- and gamma-synuclein causes an increase in release probability from dopaminergic synapses PMID: 18333965
    14. Mice expressing high levels of gamma-synuclein develop severe and fatal neurological disease. PMID: 19246516

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle.
  • 蛋白家族:
    Synuclein family
  • 組織特異性:
    Highly expressed in brain, particularly in the substantia nigra. Also expressed in the corpus callosum, heart, skeletal muscle, ovary, testis, colon and spleen. Weak expression in pancreas, kidney and lung. Expressed predominantly in the cell bodies and a
  • 數據庫鏈接:


主站蜘蛛池模板: 精品午夜中文字幕熟女人妻在线| 国产精品老熟女露脸视频| 加勒比无码一区二区三区| 免费无码又爽又刺激毛片| 丁香五月婷激情综合第九色| 瑜伽裤国产一区二区三区| 欧美三级a做爰在线观看| 欧美人与动性行为视频| 久久天天躁狠狠躁夜夜av浪潮| 东北女人毛多水多牲交视频| 大伊香蕉精品一区视频在线| 中文字幕乱码熟妇五十中出色欲| 东京热毛片无码dvd一二三区| 曰韩少妇内射免费播放| 亚洲男人的天堂在线播放| 久久www免费人成_看片中文| 亚洲成av人片天堂网九九| 国产成人啪精品视频免费网站软件| 亚洲va欧美va天堂v国产综合| 无码无套少妇毛多18pxxxx| 美女又色又爽视频免费| 久久婷婷五月综合色俺也想去 | 国产人妻大战黑人20p| 久久综合给合久久狠狠97色| 男人天堂2018亚洲男人天堂| 欧美人与动牲交zooz男人| 亚洲精品乱码久久久久久不卡| 色婷婷综合久久久中文字幕| 国产免费一区二区三区不卡| 国产美女精品自在线拍免费| 无码免费午夜福利看片| 日本三级成本人网站| 激情内射亚洲一区二区三区爱妻| 暖暖视频日本| 亚洲欧洲国产成人综合在线观看 | 欧美日激情日韩精品嗯| 97超碰精品成人国产| 天天做天天爱天天综合网| 久久国产精品-国产精品| 国产精品久久久影视青草| 久久国产中文娱乐网|