在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Gamma-aminobutyric acid receptor subunit beta-2 (Gabrb2), partial

  • 中文名稱:
    小鼠Gabrb2重組蛋白
  • 貨號:
    CSB-YP009147MO
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    小鼠Gabrb2重組蛋白
  • 貨號:
    CSB-EP009147MO
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    小鼠Gabrb2重組蛋白
  • 貨號:
    CSB-EP009147MO-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小鼠Gabrb2重組蛋白
  • 貨號:
    CSB-BP009147MO
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小鼠Gabrb2重組蛋白
  • 貨號:
    CSB-MP009147MO
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Gabrb2
  • Uniprot No.:
  • 別名:
    Gabrb2; Gabrb-2Gamma-aminobutyric acid receptor subunit beta-2; GABA(A) receptor subunit beta-2
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain. Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel. The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer. The alpha1/beta2/gamma2 receptor and the alpha2/beta2/gamma2 receptor exhibit synaptogenic activity. Functions also as histamine receptor and mediates cellular responses to histamine.
  • 基因功能參考文獻:
    1. Rebound potentiation is an input-specific plasticity that occurs only at basket cell-Purkinje cell inhibitory synapses and critically relies on GABAA receptors containing the beta2-subunit. PMID: 26179122
    2. Gabrb2 receptor subunits are expressed in interneurons of the dentate gyrus along with alpha1 and delta subunits. PMID: 24055402
    3. The gamma2 subunits (of GABA A receptors) interacted with Beta2 subunit N-glycans and subdomains containing the glycosylation sites. PMID: 24213971
    4. In an epileptic stargazer mouse model, Gabrb2 receptor subunit expression in the ventral thalamus is increased. PMID: 24417662
    5. These studies identify a novel gephyrin-binding motif in GABA(A) R beta2 and beta3 large cytoplasmic loops. PMID: 23205938
    6. Data indicate that the expression levels of [beta]2/3 GABAAR showed 2.81 +/- 0.08-fold and 3.83 +/- 0.07-fold increases, respectively, in the pancreatectomized mice 3 and 14 days after surgery. PMID: 23486367
    7. deletion of beta2 subunit of GABAA receptors reduces actions of alcohol and other drugs PMID: 12490572
    8. GABA(A) receptors interact directly with ethylmaleimide sensitive factor, a critical regulator of vesicular dependent protein trafficking. PMID: 16095914
    9. Deletion of the beta(2) subunit had no effect on the diazepam-induced current and therefore these extrasynaptic receptors do not contain this subunit. PMID: 18079158
    10. Different NMDA-receptor subunit 1 and GABA(B)-receptor subunit 2 levels observed in naive mouse strains reflect strain-dependent expression of subunits and are proposed to lead to altered stoichiometry of GABA(B)-receptor complexes. PMID: 19524116

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle.
  • 蛋白家族:
    Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily, GABRB2 sub-subfamily
  • 數據庫鏈接:

    KEGG: mmu:14401

    UniGene: Mm.338723



主站蜘蛛池模板: 成人免费午夜无码视频| 天堂最新版资源网| 国产精品美女久久久久久福利 | 五月天精品视频在线观看| www一区二区www免费| 欧洲多毛裸体xxxxx| 午夜理论片在线观看免费| 日韩欧美mv在线观看免费| 欧美顶级少妇作爱| 精品无人乱码一区二区三区的特点| 国产精品久久香蕉免费播放| 久久精品超碰av无码| 亚洲中文字幕无码中字| 激情五月色综合国产精品| 三级理论中文字幕在线播放| 亚洲中文字幕无码乱线| xx性欧美肥妇精品久久久久久| 野花社区在线www日本| 18禁止观看强奷免费国产大片| 欧美三级在线播放| 玩弄少妇高潮ⅹxxxyw| 2021久久精品国产99国产精品 | 少妇无码av无码专区在线观看| 狠狠做深爱婷婷久久综合一区| 亚洲日本中文字幕乱码在线| 中文字幕资源网| 国产麻豆精品一区二区三区v视界| 中无码人妻丰满熟妇啪啪| 香草乱码一二三四区别| 欧美性猛交aaaa片黑人| 精品无码一区二区三区电影| 娜娜麻豆国产电影| 国产良妇出轨视频在线观看| 成人亚洲精品久久久久软件| 午夜福利电影网站鲁片大全| 免费天堂无码人妻成人av电影| 欧美大成色www永久网站婷| 天堂aⅴ无码一区二区三区| 少妇久久久久久人妻无码| 成年男女免费视频网站| 精品久久久久久亚洲精品|