在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse ER degradation-enhancing alpha-mannosidase-like 1 (Edem1), partial

Recombinant Mouse ER degradation-enhancing alpha-mannosidase-like 1 (Edem1), partial

  • 中文名稱：
    小鼠Edem1重組蛋白
  • 貨號：
    CSB-YP852892MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Edem1重組蛋白
  • 貨號：
    CSB-EP852892MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Edem1重組蛋白
  • 貨號：
    CSB-EP852892MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Edem1重組蛋白
  • 貨號：
    CSB-BP852892MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Edem1重組蛋白
  • 貨號：
    CSB-MP852892MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Edem1; EdemER degradation-enhancing alpha-mannosidase-like protein 1
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2.
  • 基因功能參考文獻：
    1. Japanese encephalitis virus replication is negatively regulated by autophagy and occurs on LC3-I- and EDEM1-containing membranes PMID: 25046112
    2. Data suggest Edem1/Edem2 participate in ricin translocation; overexpression of Edem2, in contrast to Edem1, promotes ricin subunit A transport from endoplasmic reticulum (ER) to cytosol; transport of ricin P250A mutant is Edem1/Edem2-independent. PMID: 24200403
    3. analysis of a shared endoplasmic reticulum-associated degradation pathway involving the EDEM1 protein for glycosylated and nonglycosylated proteins PMID: 23233672
    4. role of the lectins Htm1p/EDEM in the degradation process of CFTR PMID: 15215312
    5. EDEM has a role in maintenance of protein folding efficiency and secretory capacity PMID: 15308654
    6. EDEM is involved in retrotranslocation of ricin from the ER to the cytosol. PMID: 16452630
    7. Cells with defective EDEM1 turnover contain unphysiologically high levels of EDEM1, show enhanced ER associated degradation activity and are characterized by impaired capacity to efficiently complete maturation of model glycopolypeptides. PMID: 18452703

    顯示更多

    收起更多

  • 亞細胞定位：
    Endoplasmic reticulum membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyl hydrolase 47 family
  • 數據庫鏈接：


主站蜘蛛池模板： 国产成人精品自在线导航| 女人18毛片水真多| 亚洲人成无码www久久久| 日本毛茸茸的丰满熟妇| 色琪琪丁香婷婷综合久久| 精品成人av一区二区三区| 久无码久无码av无码| 少妇激情av一区二区三区| 免费播放婬乱男女婬视频国产| 天天狠天天透天天伊人| 国产乱妇乱子视频在播放| 污18禁污色黄网站免费 | 无码a∨高潮抽搐流白浆| 国产成人精品日本亚洲网站| 激情内射人妻1区2区3区| 肉感饱满中年熟妇日本| 亚洲 制服 丝袜 无码 在线| 久久www免费人成看片入口| 18禁止看的免费污网站| 好男人社区www在线官网| 亚洲精品久久yy5099| 亚洲精品嫩草研究院久久| av无码精品一区二区三区| 欧美丰腴丰满大屁股熟妇| 让少妇高潮无乱码高清在线观看| 秋霞av鲁丝片一区二区| 国产精品情侣呻吟对白视频 | 中文字幕在线精品视频入口一区| 国产精品久久毛片| 东北少妇不带套对白| 久久久久欧美国产高潮| 亚洲日韩精品国产一区二区三区| 久久丫精品忘忧草西安产品| 国自产拍偷拍精品啪啪模特| 亚洲国产超清无码专区| 欧美黑人巨大videos精品| 国产成人av大片大片在线播放 | 少妇无码一区二区三区免费| 美女露出奶头扒开尿口免费网站| 尹人香蕉久久99天天拍欧美p7| 日本免费高清一本视频|