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EDEM1

ER degradation-enhancing alpha-mannosidase-like protein 1is a protein in humans that is encoded by EDEM1 gene. Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2.

EDEM1 Antibodies

EDEM1 for Homo sapiens (Human)

EDEM1 Proteins

EDEM1 Proteins for Homo sapiens (Human)

EDEM1 Proteins for Mus musculus (Mouse)