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  4. Recombinant Mouse Complement C1q tumor necrosis factor-related protein 6 (C1qtnf6)

Recombinant Mouse Complement C1q tumor necrosis factor-related protein 6 (C1qtnf6)

  • 中文名稱：
    Recombinant Mouse Complement C1q tumor necrosis factor-related protein 6(C1qtnf6)
  • 貨號：
    CSB-YP753714MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Complement C1q tumor necrosis factor-related protein 6(C1qtnf6)
  • 貨號：
    CSB-EP753714MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Complement C1q tumor necrosis factor-related protein 6(C1qtnf6)
  • 貨號：
    CSB-BP753714MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Complement C1q tumor necrosis factor-related protein 6(C1qtnf6)
  • 貨號：
    CSB-MP753714MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    C1qtnf6
  • Uniprot No.：
  • 別名：
    C1qtnf6Complement C1q tumor necrosis factor-related protein 6
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    25-264
  • 氨基酸序列
    VPTEET TFGESVASHL PKGCRRCCDP EDLMSSDDTV QAPVSPYVLP EVRPYINITI LKGDKGDRGP TGTPGKPGKN GTRGDRGSQG VKGDKGQAGS PGSSCQTHYS AFSVGRKTGL HSSENFLSLL FDRVFVNTDG HFDMATGSFV APLRGLYFFS LNVHSWNYKE TYVHIVHNEQ AVVILYAQPS ERSIMQSQSV MLPLVPGDRV WVRLFKRERE NGIYSDDVDT YITFSGHLIK AEDN
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 基因功能參考文獻：
    1. The results establish CTRP6 as a novel metabolic/immune regulator linking obesity to adipose tissue inflammation and insulin resistance. PMID: 28726640
    2. CTRP6 knockdown down-regulated the levels of lipogenic genes and phosphorylated Erk1/2 (p-Erk1/2) in the early lipogenic stage, whereas up-regulated p-Erk1/2 in the terminal differentiation in skeletal myoblasts. PMID: 27125977
    3. CTRP6 specifically suppresses the alternative pathway of the complement system. C1qtnf6(-/-) mice are highly susceptible to induced arthritis, Arthus reaction, and experimental autoimmune encephalomyelitis. PMID: 26404464
    4. Knockdown of CTRP6 can inhibit adipogenesis of 3T3-L1 adipocytes through lipogenic marker genes and Erk1/2 signaling pathway. PMID: 25639984
    5. CTRP6 plays a role in fatty acid metabolism via the AMPK-ACC pathway. The globular domain of CTRP6 mediates the phosphorylation and activation of the 5'-AMP-activated protein kinase (AMPK) in skeletal muscle cells. PMID: 20102710

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  • 亞細胞定位：
    Secreted.
  • 數據庫鏈接：


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