在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Chondroitin sulfate proteoglycan 4 (Cspg4), partial

Recombinant Mouse Chondroitin sulfate proteoglycan 4 (Cspg4), partial

  • 中文名稱：
    Recombinant Mouse Chondroitin sulfate proteoglycan 4(Cspg4) ,partial
  • 貨號：
    CSB-YP006076MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Chondroitin sulfate proteoglycan 4(Cspg4) ,partial
  • 貨號：
    CSB-EP006076MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse Chondroitin sulfate proteoglycan 4(Cspg4) ,partial
  • 貨號：
    CSB-EP006076MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Chondroitin sulfate proteoglycan 4(Cspg4) ,partial
  • 貨號：
    CSB-BP006076MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Chondroitin sulfate proteoglycan 4(Cspg4) ,partial
  • 貨號：
    CSB-MP006076MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Cspg4; An2; Kiaa4232; Ng2Chondroitin sulfate proteoglycan 4; Chondroitin sulfate proteoglycan NG2; Proteoglycan AN2
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N-terminus growth factors, extracellular matrix proteases modulating their activity. May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. May modulate the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin. Functions also as a signal transducing protein by binding through its cytoplasmic C-terminus scaffolding and signaling proteins. May promote retraction fiber formation and cell polarization through Rho GTPase activation. May stimulate alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42, ACK1 and BCAR1. May activate FAK and ERK1/ERK2 signaling cascades.
  • 基因功能參考文獻：
    1. This study confirm the earlier report that EAE disease severity is ameliorated in the absence of NG2 proteoglycan, but do not give any indication of NG2 expression by immune cells in naive and immunized mice. PMID: 28567522
    2. These findings suggest that NG2 expression mediates inflammatory reactions and neurodegeneration in microglial cells in response to central nervous system injury, potentially by regulating FAK phosphorylation. PMID: 27306838
    3. NG2 may represent a promising target for the modulation of ICAM-1-mediated immune responses. PMID: 28964848
    4. Results demonstrate that NG2 plays an important role in the induction and progression of experimental autoimmune encephalomyelitis. We further demonstrate that this role exerts itself at both the central nervous system/blood-brain barrier and immune system levels PMID: 27026411
    5. Loss of chondroitin sulfate proteoglycan NG2 (NG2) does not affect oligodendroglial differentiation. PMID: 27755537
    6. Study found significant differences in transcript and protein expression, electrophysiological properties and proliferative capacity of NG2 glia in the mouse forebrain, suggesting the co-existence of several subpopulations of NG2 glia. PMID: 27306788
    7. chondroitin sulfate proteoglycan 4 (CSPG4) is a potential mesenchymal progenitor cells marker. PMID: 27582000
    8. Results suggest that NG2 may counteract neurological deficits and adverse glial responses in traumatic brain injury PMID: 26638112
    9. NG2 protein is not required for glutamatergic neuron-NG2 cell synaptic signaling PMID: 25100858
    10. This study demonstrated that NG2 is an important factor in OPC-dependent regeneration of white matter following spinal cord demyelination. PMID: 26338007
    11. NF-kappaB in NG2(+) cells promotes myoblast migration to the tips of myofibers through cell-cell contact through expression of ephrinA5 from NG2(+) cells PMID: 26777211
    12. The NG2 proteoglycan protects oligodendrocyte precursor cells against oxidative stress via interaction with OMI/HtrA2. PMID: 26340347
    13. NG2 ablation leads to reduced LDL sequestration in the aorta and reduced atherogenesis. PMID: 26543095
    14. This study demonstrated that a pathway and role for NG2 glia in central nerve system homeostasis and mood disorders. PMID: 26606998
    15. cleaved by ADAM10 and the gamma-secretase on oligodendrocyte precursor cells PMID: 25387269
    16. The results of this study indicated that endogenous netrin-1 plays a role in NG2(+) glial cell homeostasis that is distinct from its role in myelination. PMID: 25926469
    17. The study demonstrates changes in pericyte expression of NG2 and PDGFRB and vascular permeability in the sensory circumventricular organs by chronic osmotic stimulation. PMID: 23629811
    18. NG2 knockdown results in loss of beta1 integrin activation in endothelial cells, revealing a mechanism for NG2-dependent cross talk between pericytes and endothelial cells. PMID: 23925489
    19. Data show that neurofibromatosis type 1 (NF1)-inactivation results in a cell-autonomous increase in glial fibrillary acidic protein+ (GFAP+), but not in NG2 proteoglycan NG2+, cell proliferation in vitro. PMID: 23318450
    20. As soon as cells exit mitosis, a fraction of NG2-expressing cells displays accumulation of G protein-coupled receptor (GPR)17 protein in the Golgi apparatus. PMID: 21956849
    21. Traumatic brain injury results in an increase in the chondroitin sulfate proteoglycans (CSPGs) neurocan and NG2 expression in a tight band surrounding the injury core. PMID: 22628090
    22. the importance of NG2 in mediating pericyte/endothelial cell communication that is required for proper vessel maturation and function PMID: 22531600
    23. brown fat dysfunction in NG2 null mice results from deficits in the recruitment and/or development of brown pre-adipocytes PMID: 22295099
    24. These studies identify NG2 as an important factor in regulating myelin processing. PMID: 22078261
    25. Overexpression of CSPG4 is associated with tumour growth and angiogenesis in glioblastoma multiforme and melanoma PMID: 21829586
    26. Results suggest that NG2 cells are unlikely to play an inhibitory boundary role on TCA growth and that NG2 expression is not necessary for normal barrel formation. PMID: 21292011
    27. PDGF-B-driven gliomagenesis can occur in the absence of the proteoglycan NG2 PMID: 20939912
    28. live cell imaging of single NG2 cells from early postnatal brain slices revealed that NG2 cells initially divide symmetrically to produce two daughter NG2 cells and that differentiation into oligodendrocytes occurred after 2-3 days PMID: 21266410
    29. NG2 expressing cells constitute the major immature population of the mouse cortex, since not only oligodendrocyte precursor cells and pre-oligodendrocytes but also a part of the glial-restricted progenitors express the NG2 proteoglycan. PMID: 21072997
    30. a stable population of quiescent NG2 cells appears before the end of the first postnatal week and persists throughout life PMID: 20346197
    31. NG2 may promote OPC proliferation via enhancement of growth factor signaling or mediation of OPC interaction with unmyelinated axons. PMID: 20006679
    32. a population of cortical NG2(+) cells display physiological properties that differ from their white matter counterparts. PMID: 15358811
    33. dendritic cell-based immunization represents an effective strategy to implement T cell-based immunotherapy targeting high molecular weight-melanoma-associated antigen (HMW-MAA) in patients with HMW-MAA-bearing tumors [HMW-MAA] PMID: 16455987
    34. The NG2 null epidermis does not achieve its full thickness due to reduced proliferation of basal keratinocytes that serve as the stem cell population in this layer. Thickening of the subcutis is delayed due to deficiencies in the adipocyte population. PMID: 18040080
    35. syntenin plays a role in the migration of oligodendroglial precursors, and we suggest that NG2-syntenin-1 interactions contribute to this PMID: 18218632
    36. mice expressed the NG2 protein in all regions and at all ages studied PMID: 18924152
    37. These observations indicate that NG2 cells serve as precursor cells for oligodendrocytes and a subpopulation of protoplasmic astrocytes throughout the rostrocaudal axis of the CNS. PMID: 19006598
    38. Results indicate that NG2 cells do not represent neuronal progenitor cells in the postnatal SVZ but are likely to be oligodendrocyte precursor cells. PMID: 19058188
    39. murine GL261 cerebral gliomas express AN2 and HMP-specific mAb VT68.2 accumulates selectively and specifically at high concentration and is retained within murine cerebral gliomas PMID: 19152070

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein; Extracellular side. Apical cell membrane; Single-pass type I membrane protein; Extracellular side. Cell projection, lamellipodium membrane; Single-pass type I membrane protein; Extracellular side. Cell surface.
  • 組織特異性：
    Expressed in microcascular pericytes and not endothelial cells.
  • 數據庫鏈接：


主站蜘蛛池模板： 亚洲中文字幕永久在线全国| 国产美女精品一区二区三区 | 欧亚乱熟女一区二区在线| 国产精品永久免费视频| 青青草无码伊人久久| 最新国产精品久久精品| 亚洲人ⅴsaⅴ国产精品| 亚洲综合无码精品一区二区三区| 中文字幕av伊人av无码av| 加勒比中文字幕无码一区| 亚洲欧美日韩一区在线观看| 老太脱裤让老头玩ⅹxxxx| 夜色福利院在线观看免费| 国产精品白丝喷浆| 午夜福利啪啪片| 日本体内she精高潮| 国产熟妇午夜精品aaa| 日本高清www无色夜在线视频| 国精产品一区一区三区| 亚洲一区二区三区高清av| 欧美亚洲日韩国产综合电影| 亚洲欧美成人一区二区在线| 妺妺窝人体色www聚色窝| 成人午夜高潮a∨猛片| 精品无人区码一码二码三码区别 | 色又黄又爽18禁免费视频| 中文日产幕无线码6区收藏| 欧美极品少妇无套实战| 99精品国产在热久久| 中文字幕丰满孑伦无码精品| 久久三级中文欧大战字幕| 内射女校花一区二区三区| 欧美黑人巨大xxxxx| 成人亚洲欧美一区二区三区| 亚洲人成电影综合网站色www| 亚洲精品成a人在线观看| 亚洲永久网址在线观看| 亚洲第一最快av网站| 成人国产一区二区精品小说| 国产精品视频一区二区噜噜| 女人裸体做爰免费视频|