在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (Ndst2), partial

In Stock
  • 中文名稱:
    小鼠Ndst2重組蛋白
  • 貨號:
    CSB-EP015615MO
  • 規(guī)格:
    ¥2328
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    Ndst2
  • Uniprot No.:
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Partial
  • 來源:
    E.coli
  • 分子量:
    40.3 kDa
  • 表達區(qū)域:
    598-883aa
  • 氨基酸序列
    KTCDRLPKFLIVGPQKTGTTAIHFFLSLHPAVTSSFPSPSTFEEIQFFNGPNYHKGIDWYMDFFPVPSNASTDFLFEKSATYFDSEVVPRRGAALLPRAKIITVLINPADRAYSWYQHQRAHGDPIALNYTFYQVISASSQAPLLLRSLQNRCLVPGYYSTHLQRWLTYYPSGQLLIMDGQELRVNPAASMEIIQKFLGITPFLNYTRTLRFDEDKGFWCQGLEGGKTRCLGRSKGRRYPDMDMESRLFLTDFFRNHNLELSKLLSRLGQPAPLWLREELQHSSVG
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged and C-terminal Myc-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Required for the exosomal release of SDCBP, CD63 and syndecan.
  • 基因功能參考文獻:
    1. Size estimation of heparan sulfate polysaccharide chains indicated that increased chain lengths in NDST2-overexpressing cells alone could explain the increased heparan sulfate content. A model is discussed where NDST2-specific substrate modification stimulates elongation resulting in increased heparan sulfate chain length. PMID: 27387504
    2. embryonic stem cells lacking both NDST1 and NDST2, expressing a very low sulfated heparan sulfate, can take the initial step toward differentiation into all three germ layers PMID: 22298785
    3. although NDST-2(-/-) mice demonstrate an altered response in interstitial fulid pressure after mast cell activation, there was no similar alteration after neurogenic inflammation PMID: 14604857
    4. NDST-2 does not contribute significantly to tissue-specific Heparan Sulfate structures PMID: 15292174
    5. NDST1 and NDST2 have roles in N-sulfation but not in 6-O-sulfation of heparan sulfate PMID: 15319440
    6. analysis of liver NDST1 and NDST2 biosynthesis PMID: 16984905
    7. expression of N-deacetylase/N-sulfotransferase (NDST)-2, a key enzyme in mast cell maturation PMID: 19915053

    顯示更多

    收起更多

  • 亞細胞定位:
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族:
    Sulfotransferase 1 family, NDST subfamily
  • 組織特異性:
    Widely expressed in adult and throughout development.
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 日本电影一区二区三区| 精品久久久久香蕉网| 亚洲伊人成综合网2222| 亚洲国产中文在线二区三区免| 久久久精品人妻一区二区三区| 曰本无码不卡高清av一二| 忘忧草日本在线播放www| 无码日韩人妻av一区免费| 蜜桃av麻豆av果冻传媒| 狠狠的干性视频| 少妇挑战黑人高潮惨叫| 双乳奶水饱满少妇呻吟免费看 | 欧美不卡无线在线一二三区观| 国产成人无码视频网站在线观看| 亚洲国产精品va在线看黑人| 人人妻人人爽人人做夜欢视频 | 欧美日韩国产精品| 日产一区日产2区| 真人做人试看60分钟免费视频| 国产69精品久久久久孕妇| 欧美精品国产综合久久| 毛片24种姿势无遮无拦| 国产成人av免费网址| 小12箩利洗澡无码视频网站| 性色av免费网站| 精品三级av无码一区| 天天综合网久久综合免费人成| 99国产精品欧美一区二区三区| 亚洲一区二区三区写真| 尤物yw午夜国产精品大臿蕉| 日本少妇寂寞少妇aaa| 日本边添边摸边做边爱的网站| 国产精品亚洲成在人线| 久久婷婷五月综合色俺也想去| 亚洲精品久久久狠狠爱小说| 影音先锋在线资源无码| 免费看撕开奶罩揉吮奶头视频| 无码国内精品久久综合88| 少妇脱了内裤让我添| 国产巨大爆乳在线观看| 国产欧美精品一区二区色综合|