在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse B-lymphocyte antigen CD20 (Ms4a1), partial

In Stock
  • 中文名稱:
    小鼠Ms4a1重組蛋白
  • 貨號:
    CSB-YP015007MO2
  • 規格:
    ¥2208
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    Ms4a1; Cd20; Ly-44; Ms4a2; B-lymphocyte antigen CD20; B-cell differentiation antigen Ly-44; Lymphocyte antigen 44; Membrane-spanning 4-domains subfamily A member 1; CD antigen CD20
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Partial
  • 來源:
    Yeast
  • 分子量:
    20.1kDa
  • 表達區域:
    132-291aa
  • 氨基酸序列
    ILNMTLSHFLKMRRLELIQTSKPYVDIYDCEPSNSSEKNSPSTQYCNSIQSVFLGILSAMLISAFFQKLVTAGIVENEWKRMCTRSKSNVVLLSAGEKNEQTIKMKEEIIELSGVSSQPKNEEEIEIIPVQEEEEEEAEINFPAPPQEQESLPVENEIAP
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR.
  • 基因功能參考文獻:
    1. Our findings indicate that anti-CD20-IFNalpha eradicates B-cell lymphoma by employing tumor cells as antigen-presenting cells to reactivate tumor-infiltrating CD8(+) T cells and synergizing with anti-PD-L1 treatment PMID: 28533311
    2. Galectin-1 has a role in driving lymphoma CD20 immunotherapy resistance in a mouse model PMID: 26888257
    3. Results indicate that an antigen-specific B cell response towards intracellular pathogens can be generated during anti-CD20 depletion therapy. PMID: 26261496
    4. this study demonstrates a role for CD20 in B cell activation and T-dependent humoral immunity. PMID: 23966626
    5. CD20 is required for store-operated calcium entry in C2C12 myoblasts. PMID: 22982241
    6. immunization of mice with the CD20 extracellular domain-6 using Freund's or QS-21 adjuvants was shown to exert significant biological effects in vivo with the pronounced depletion of splenic B cells. PMID: 20189250
    7. type I CD20 antibody cytotoxicity critically depends on Fc receptor ITAM signaling PMID: 20354182
    8. CD20 deficiency in humans results in impaired T cell-independent antibody responses. PMID: 20038800
    9. review of structure, function, tissue and cell distribution PMID: 12144126
    10. Anti-CD20 antibodies rapidly depleted the vast majority of circulating and tissue B cells in an isotype-restricted manner dependent on effector cell Fc receptor expression. PMID: 15210744
    11. expression in bacterial cells; isolation and biophysical and structural studies PMID: 16285718
    12. In mice treated with anti-CD20 mAb, development of arthritis was significantly reduced in comparison to control mAb-treated mice PMID: 18354225
    13. involvement of CD20 in calcium influx PMID: 18474602

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein. Cell membrane; Lipid-anchor.
  • 蛋白家族:
    MS4A family
  • 數據庫鏈接:


主站蜘蛛池模板: 欧美成人aaa片一区国产精品| 亚洲无线卡一卡二| 国产乡下三级全黄三级| 无码中文字幕色专区| 久久精品成人免费国产| 国产丝袜足j在线视频播放| 久久久久中文伊人久久久| 久久亚洲色www成人不卡| 亚洲一区二区三区四区| 又粗又大又硬又长又爽| 在线观看国产成人av片| 免费人成再在线观看视频| 欲香欲色天天综合和网| 国产999精品久久久久久| 猫咪www免费人成网站无码| 亚洲精品久久久无码大桥未久| 鲁鲁狠狠狠7777一区二区 | 国产女人抽搐喷浆视频| 成人艳情一二三区| 国产手机在线国内精品| 亚洲欧洲自偷自拍图片| 熟妇的奶头又大又粗视频| 欧美黑人巨大xxxxx| 国产精成人品一区| 茄子在线看片免费人成视频| 丝袜美腿一区二区三区| 97香蕉碰碰人妻国产欧美| 国产96在线 | 韩国| 波多野结av在线无码中文| 亚洲 a v无 码免 费 成 人 a v | 三上悠亚久久精品| 无码国产乱人伦偷精品视频| 在线看片免费人成视频在线影院 | 伊人久久精品无码av一区| 国产伦精品一区二区三区免费| 97影院理论片手机在线观看| 国产亚洲精品福利视频在线观看 | 色惰日本视频网站www| 色综合久久久无码中文字幕波多 | 永久免费的av片在线电影网| 亚洲欧美在线观看品|