在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Alpha-2-macroglobulin receptor-associated protein (Lrpap1), partial

In Stock
  • 中文名稱:
    小鼠Lrpap1重組蛋白
  • 貨號(hào):
    CSB-BP013104MO1(M)e4
  • 規(guī)格:
    ¥3168
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    Heparin-binding protein 44 (HBP-44) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP)
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度:
    Partial
  • 來源:
    Baculovirus
  • 分子量:
    42 kDa
  • 表達(dá)區(qū)域:
    248-360aa(H294F,H296F,Y297C,H305F)
  • 氨基酸序列
    GYGSTTEFEEPRVIDLWDLAQSANFTEKELESFREELKHFEAKIEKFNFCQKQLEISFQKLKHVESIGDPEHISRNKEKYVLLEEKTKELGYKVKKHLQDLSSRVSRARHNEL
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal GFP-tagged and C-terminal 6xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway.
  • 基因功能參考文獻(xiàn):
    1. RAP deficiency attenuated atherosclerosis without influencing abdominal aortic aneurysms in hypercholesterolemic mice infused with angiotensin II. PMID: 22153700
    2. Findings reveal that RAP is a novel Abeta-binding protein that promotes cellular internalization of Abeta. PMID: 19826010
    3. In RAP-deficient mice megalin expression was strongly reduced and restricted to a subapical localization and NaP(i)-IIa protein distribution and abundance in the kidney was not altered. PMID: 12748857
    4. the His-sRAP-induced acceleration of megalin-mediated endocytosis causes phosphaturia via altered subcellular distribution of NaPi-II [39-kD receptor-associated protein (RAP)] PMID: 15976002
    5. Results suggest that receptor-associated protein is required for the establishment of thyroglobulin reservoirs, but its absence does not affect hormone secretion. PMID: 16306127
    6. RAP is expressed by thyrocytes in a TSH-dependent manner, both in cultured thyroid cells and in vivo PMID: 17123336
    7. Disruption of the RAP gene determines not only thyroid abnormalities, but also a severe defect of megalin expression and function in the kidney. PMID: 18296906
    8. Receptor-associated protein (RAP) plays a central role in modulating Abeta deposition in APP/PS1 transgenic mice PMID: 18776935

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Rough endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment lumen. Golgi apparatus, cis-Golgi network. Golgi apparatus lumen. Endosome lumen. Cell surface.
  • 蛋白家族:
    Alpha-2-MRAP family
  • 組織特異性:
    Highly expressed in PYS-2 parietal endoderm cells and in the kidney. The RNA level increased about 10-fold during differentiation of F9 embryonal carcinoma cells to parietal endoderm cells.
  • 數(shù)據(jù)庫(kù)鏈接:


主站蜘蛛池模板: 亚洲va综合va国产产va中文| 欧美男生射精高潮视频网站| 深夜福利啪啪片| 午夜福利电影网站鲁片大全| 天天躁夜夜躁狠狠综合2020| 无码国产成人午夜电影在线观看| 国产乱人伦在线播放| 免费情侣作爱视频| 四虎永久在线精品8848a| 亚洲精品午夜国产va久久成人| 亚洲乱亚洲乱少妇无码99p| 在线高清亚洲精品二区| 日本japanese丰满多毛| 国产欧美va天堂在线观看视频 | 人妻无码中文专区久久五月婷 | 免费无码又爽又刺激激情视频软件 | 欧美video性欧美熟妇| 51福利国产在线观看午夜天堂| 免费观看黄网站在线播放| 99精品无码一区二区| 一本久久伊人热热精品中文字幕| 欧美成人午夜免费影院手机在线看 | 国产99在线 | 亚洲| 美女视频黄的全免费视频网站| 久久精品99久久香蕉国产| 精品国产一区二区三区av性色| 一二三区乱码不卡手机版| 亚洲精品国产一区二区在线观看| 久久久久人妻一区精品性色av | 欧美成人片一区二区三区| 无码免费一区二区三区免费播放 | 亚洲欧洲无卡二区视頻| 国产sm精品调教视频网址| 伊人久久大香线蕉亚洲五月天| 天天噜噜噜在线视频| 久久久久精品无码一区二区三区 | 四虎影视在线观看2413| 国产美女在线精品免费观看 | 国产精品亚洲а∨天堂| 天天夜碰日日摸日日澡性色av| 国产成人av一区二区三区在线 |