在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Alpha-2-macroglobulin receptor-associated protein (Lrpap1), partial

  • 中文名稱:
    小鼠Lrpap1重組蛋白
  • 貨號:
    CSB-MP013104MO1(M)e5
  • 規格:
    ¥696
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    Heparin-binding protein 44
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Partial
  • 來源:
    Mammalian cell
  • 分子量:
    43.4 kDa
  • 表達區域:
    248-360aa(H294F,H296F,Y297C,H305F)
  • 氨基酸序列
    GYGSTTEFEEPRVIDLWDLAQSANFTEKELESFREELKHFEAKIEKFNFCQKQLEISFQKLKHVESIGDPEHISRNKEKYVLLEEKTKELGYKVKKHLQDLSSRVSRARHNEL
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal GFP-tagged and C-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    18-28 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway.
  • 基因功能參考文獻:
    1. RAP deficiency attenuated atherosclerosis without influencing abdominal aortic aneurysms in hypercholesterolemic mice infused with angiotensin II. PMID: 22153700
    2. Findings reveal that RAP is a novel Abeta-binding protein that promotes cellular internalization of Abeta. PMID: 19826010
    3. In RAP-deficient mice megalin expression was strongly reduced and restricted to a subapical localization and NaP(i)-IIa protein distribution and abundance in the kidney was not altered. PMID: 12748857
    4. the His-sRAP-induced acceleration of megalin-mediated endocytosis causes phosphaturia via altered subcellular distribution of NaPi-II [39-kD receptor-associated protein (RAP)] PMID: 15976002
    5. Results suggest that receptor-associated protein is required for the establishment of thyroglobulin reservoirs, but its absence does not affect hormone secretion. PMID: 16306127
    6. RAP is expressed by thyrocytes in a TSH-dependent manner, both in cultured thyroid cells and in vivo PMID: 17123336
    7. Disruption of the RAP gene determines not only thyroid abnormalities, but also a severe defect of megalin expression and function in the kidney. PMID: 18296906
    8. Receptor-associated protein (RAP) plays a central role in modulating Abeta deposition in APP/PS1 transgenic mice PMID: 18776935

    顯示更多

    收起更多

  • 亞細胞定位:
    Rough endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment lumen. Golgi apparatus, cis-Golgi network. Golgi apparatus lumen. Endosome lumen. Cell surface.
  • 蛋白家族:
    Alpha-2-MRAP family
  • 組織特異性:
    Highly expressed in PYS-2 parietal endoderm cells and in the kidney. The RNA level increased about 10-fold during differentiation of F9 embryonal carcinoma cells to parietal endoderm cells.
  • 數據庫鏈接:


主站蜘蛛池模板: 国产成人手机高清在线观看网站| 久久精品无码av| 精品欧美一区二区三区久久久| 可以看三级的网站| 中文人妻无码一区二区三区| 日本孕妇潮喷高潮视频| 一区二三区国产好的精华液o9 | 欧美黑人又大又粗xxxxx| 少妇高潮流白浆在线观看| 黄网站免费永久在线观看下载| 米奇7777狠狠狠狠视频影院 | 老外和中国女人毛片免费视频| 色伊人亚洲综合网站| 大陆国产乱人伦| 国产精品无码嫩草地址更新| 国产精品一品二区三区的使用体验 | 国内午夜国产精品小视频| 综合自拍亚洲综合图区高清| 四虎成人精品无码| 日韩精品一区二区三区免费视频| 丝袜高跟麻麻浓精受孕人妻| 熟女丝袜潮喷内裤视频网站| 国产亚洲精久久久久久无码| 国产肥白大熟妇bbbb| 国产成人av免费网址| 精品无码久久久久久尤物| 日日夜夜撸啊撸| 久激情内射婷内射蜜桃| 久久精品国产99久久6动漫 | 亚洲精品国偷拍自产在线观看蜜臀| 男人a天堂手机在线版| 中文字幕精品亚洲无线码vr | 日本成本人片视频免费| 亚洲大片av毛片免费| 综合久久给合久久狠狠狠97色 | 精品国际久久久久999| 国产成人av大片在线观看| 妺妺窝人体色www看人体| 久久精品无码一区二区无码| 十八禁午夜福利免费网站| 激情欧美成人久久综合|