在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Alpha-2-macroglobulin receptor-associated protein (Lrpap1), partial

  • 中文名稱:
    小鼠Lrpap1重組蛋白
  • 貨號:
    CSB-MP013104MO1(M)e5
  • 規格:
    ¥696
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    Heparin-binding protein 44
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Partial
  • 來源:
    Mammalian cell
  • 分子量:
    43.4 kDa
  • 表達區域:
    248-360aa(H294F,H296F,Y297C,H305F)
  • 氨基酸序列
    GYGSTTEFEEPRVIDLWDLAQSANFTEKELESFREELKHFEAKIEKFNFCQKQLEISFQKLKHVESIGDPEHISRNKEKYVLLEEKTKELGYKVKKHLQDLSSRVSRARHNEL
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal GFP-tagged and C-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    18-28 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway.
  • 基因功能參考文獻:
    1. RAP deficiency attenuated atherosclerosis without influencing abdominal aortic aneurysms in hypercholesterolemic mice infused with angiotensin II. PMID: 22153700
    2. Findings reveal that RAP is a novel Abeta-binding protein that promotes cellular internalization of Abeta. PMID: 19826010
    3. In RAP-deficient mice megalin expression was strongly reduced and restricted to a subapical localization and NaP(i)-IIa protein distribution and abundance in the kidney was not altered. PMID: 12748857
    4. the His-sRAP-induced acceleration of megalin-mediated endocytosis causes phosphaturia via altered subcellular distribution of NaPi-II [39-kD receptor-associated protein (RAP)] PMID: 15976002
    5. Results suggest that receptor-associated protein is required for the establishment of thyroglobulin reservoirs, but its absence does not affect hormone secretion. PMID: 16306127
    6. RAP is expressed by thyrocytes in a TSH-dependent manner, both in cultured thyroid cells and in vivo PMID: 17123336
    7. Disruption of the RAP gene determines not only thyroid abnormalities, but also a severe defect of megalin expression and function in the kidney. PMID: 18296906
    8. Receptor-associated protein (RAP) plays a central role in modulating Abeta deposition in APP/PS1 transgenic mice PMID: 18776935

    顯示更多

    收起更多

  • 亞細胞定位:
    Rough endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment lumen. Golgi apparatus, cis-Golgi network. Golgi apparatus lumen. Endosome lumen. Cell surface.
  • 蛋白家族:
    Alpha-2-MRAP family
  • 組織特異性:
    Highly expressed in PYS-2 parietal endoderm cells and in the kidney. The RNA level increased about 10-fold during differentiation of F9 embryonal carcinoma cells to parietal endoderm cells.
  • 數據庫鏈接:


主站蜘蛛池模板: 久久99精品久久只有精品| 精品国产一区二区三区色欲| 日本高清一二三不卡区| 久久久99精品成人片| 久久久久国产精品人妻aⅴ果冻| 国产成人精品123区免费视频| 国产激情综合五月久久| 久久亚洲精品成人无码网站夜色 | 97久久国产露脸精品国产| 在线观看国产午夜福利片| 青青视频免费观看免费| 国产亚洲欧美精品永久| 亚洲欧美国产精品久久久久久久| 日本丰满少妇xxxx| 国产精品女人呻吟在线观看| 久久99精品国产99久久6男男| 国产一区二区三区不卡av| 国产久热精品无码激情 | 亚洲人成电影网站色www| 久久婷婷是五月综合色| 亚洲春色在线视频| 精品三级av无码一区| 亚洲成av人在线观看天堂无码| 亚洲午夜福利院在线观看| 中文字幕人成乱码熟女| 欧美gv在线观看| 久久99亚洲含羞草影院| 精品无码成人网站久久久久久| 色噜噜狠狠狠狠色综合久一| 精品久久久久久无码中文字幕一区 | 伊伊人成亚洲综合人网| 国产一区二区三区不卡在线观看| 97色伦图片97综合影院| 秋霞人妻无码中文字幕| 人妻中出无码一区二区三区| 人妻少妇熟女javhd| 亚洲夜夜性无码| 老司机无码精品a| 欧美三級片黃色三級片黃色| 2019国产品在线视频| 女人与拘做受全过程免费视频|