在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Alkaline ceramidase 1 (Acer1), partial

Recombinant Mouse Alkaline ceramidase 1 (Acer1), partial

  • 中文名稱：
    Recombinant Mouse Alkaline ceramidase 1(Acer1),partial
  • 貨號：
    CSB-YP001151MO1
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Alkaline ceramidase 1(Acer1),partial
  • 貨號：
    CSB-EP001151MO1
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse Alkaline ceramidase 1(Acer1),partial
  • 貨號：
    CSB-EP001151MO1-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Alkaline ceramidase 1(Acer1),partial
  • 貨號：
    CSB-BP001151MO1
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Alkaline ceramidase 1(Acer1),partial
  • 貨號：
    CSB-MP001151MO1
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Acer1; Asah3; Alkaline ceramidase 1; AlkCDase 1; Alkaline CDase 1; maCER1; Acylsphingosine deacylase 3; N-acylsphingosine amidohydrolase 3
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Endoplasmic reticulum ceramidase that catalyzes the hydrolysis of ceramides into sphingosine and free fatty acids at alkaline pH. Ceramides, sphingosine, and its phosphorylated form sphingosine-1-phosphate are bioactive lipids that mediate cellular signaling pathways regulating several biological processes including cell proliferation, apoptosis and differentiation. Exhibits a strong substrate specificity towards the natural stereoisomer of ceramides with D-erythro-sphingosine as a backbone and has a higher activity towards very long-chain unsaturated fatty acids like the C24:1-ceramide. May also hydrolyze dihydroceramides to produce dihydrosphingosine. ACER1 is a skin-specific ceramidase that regulates the levels of ceramides, sphingosine and sphingosine-1-phosphate in the epidermis, mediates the calcium-induced differentiation of epidermal keratinocytes and more generally plays an important role in skin homeostasis.
  • 基因功能參考文獻：
    1. Loss of Acer1 elevated the levels of various ceramides and sphingoid bases in the skin and caused progressive hair loss in mice. PMID: 29056331
    2. In conclusion, the present study unraveled ceramidase as a crucial player in sphingosine-induced platelet activation following GPVI-dependent signaling. PMID: 29395079
    3. novel alkaline ceramidase with a stringent substrate specificity and is selectively expressed in skin and may have a role in regulating the levels of bioactive lipids ceramide and sphingosine-1-p, as well as complex sphingolipids. PMID: 12783875
  • 亞細胞定位：
    Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Alkaline ceramidase family
  • 組織特異性：
    Highly expressed in skin. Weakly or not expressed in other tissues. Expressed by granular layer of interfollicular epidermis, sebaceous glands and infundibulum.
  • 數據庫鏈接：


主站蜘蛛池模板： 欧美黑人又粗又大久久久| 失禁潮痉挛潮喷av在线无码| 亚洲va综合va国产产va中文| 亚洲欧美v国产一区二区| 在线天堂资源www| 久久精品aⅴ无码中文字字幕蜜桃| 国产免国产免‘费| 国产 高清 无码 在线播放| 2019久久久最新精品| 国内精品视频一区二区三区| 少妇荡乳情欲办公室456视频| 欧美牲交a欧美牲交aⅴ图片| 午夜性色福利在线视频福利| 久久人搡人人玩人妻精品 | 免费福利视频一区二区三区高清| 亚洲精品nv久久久久久久久久| 国产私人尤物无码不卡| 亚洲日韩小电影在线观看| 欧美自拍亚洲综合图区| 狠狠躁夜夜躁av网站中文字幕| 成在人线av无码免费看| 亚洲精品无码乱码成人| 在线精品国产一区二区三区| 香蕉久久久久久av成人| 免费人成视频网站在线下载| 欧美va久久久噜噜噜久久| 无码日韩精品一区二区人妻| а√天堂资源中文在线官网| 亚洲精品午夜理伦不卡在线观看 | 日本无遮挡真人祼交视频| 永久免费无码av在线网站| 大白肥妇bbvbbw高潮| 国产亚洲精品久久久久秋霞| 侵犯强奷高清无码| 特黄三级又爽又粗又大| 另类内射国产在线| 伊人久久大香线蕉在观看| 中文字幕 亚洲精品 第1页| 人妻 日韩 欧美 综合 制服| 亚洲国产一区二区三区在观看| 影音先锋啪啪av资源网站|