在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Adipolin (C1QTNF12)

  • 中文名稱:
    Recombinant Mouse Adipolin(C1QTNF12)
  • 貨號:
    CSB-YP840280MO
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Mouse Adipolin(C1QTNF12)
  • 貨號:
    CSB-EP840280MO-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Mouse Adipolin(C1QTNF12)
  • 貨號:
    CSB-MP840280MO
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    C1qtnf12
  • Uniprot No.:
  • 別名:
    C1qtnf12; C1qdc2; Ctrp12; Fam132a; Adipolin; Adipose-derived insulin-sensitizing factor; Complement C1q tumor necrosis factor-related protein 12) [Cleaved into: Adipolin fC1QTNF12; Adipolin fCTRP12; Adipolin full-length form); Adipolin gC1QTNF12; Adipolin cleaved form; Adipolin gCTRP12)]
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    22-308
  • 氨基酸序列
    RQELKKSRQ LFARVDSPNI TTSNREGFPG SVKPPEASGP ELSDAHMTWL NFVRRPDDGS SRKRCRGRDK KSRGLSGLPG PPGPPGPPGP PGSPGVGVTP EALLQEFQEI LKEATELRFS GLPDTLLPQE PSQRLVVEAF YCRLKGPVLV DKKTLVELQG FQAPTTQGAF LRGSGLSLSL GRFTAPVSAI FQFSASLHVD HSELQGRGRL RTRDMVRVLI CIESLCHRHT SLEAVSGLES NSRVFTVQVQ GLLHLQSGQY VSVFVDNSSG AVLTIQNTSS FSGMLLGT
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via the PI3K-Akt signaling pathway. Administration lead to reduction of blood glucose. Able to attenuate inflammation in fat tissue.; Acts by activating the Akt signaling in hepatocytes and adipocytes. Not able to increase insulin-stimulated glucose uptake in adipocytes.; Acts by activating the MAP kinase. Increases insulin-stimulated glucose uptake in adipocytes.
  • 基因功能參考文獻:
    1. Loss of a single Ctrp12 allele affects glucose and lipid metabolism. PMID: 27815536
    2. mRNA expression of Fam132a, which encodes a newly identified insulin-sensitizing adipokine, adipolin, is significantly upregulated in the absence of KLF3. PMID: 23633521
    3. These data suggest that obesity states facilitate the cleavage of adipolin presumably through upregulation of furin in adipose tissue. PMID: 23068097
    4. The aim of this study was to demonstrate adipolin expression in human and murine chondrocytes and to elucidate the intracellular mechanism involved in adipolin basal expression PMID: 22736092
    5. Endopeptidase cleavage generates a functionally distinct isoform of C1q/tumor necrosis factor-related protein-12 (CTRP12) with an altered oligomeric state and signaling specificity. PMID: 22942287
    6. CTRP12 as a novel metabolic regulator linking adipose tissue to whole body glucose homeostasis through insulin-dependent and independent mechanisms. PMID: 22275362
    7. Adipolin/C1qdc2/CTRP12 protein functions as an adipokine that improves glucose metabolism PMID: 21849507

    顯示更多

    收起更多

  • 亞細胞定位:
    [Adipolin fC1QTNF12]: Secreted.; [Adipolin gC1QTNF12]: Secreted.
  • 蛋白家族:
    Adipolin/erythroferrone family
  • 組織特異性:
    Widely expressed, with high expression in subcutaneous and epididymal white adipose tissues and brown adipose tissue. Expressed in adipocytes (at protein level).
  • 數據庫鏈接:


主站蜘蛛池模板: 无码乱码av天堂一区二区| 97色偷偷色噜噜男人的天堂| 久久精品手机观看| 伊人久久大香线蕉av色婷婷色| 国产亚洲精品久久久久秋霞| 亚洲国产午夜精品理论片妓女| 天堂va欧美ⅴa亚洲va在线| 亚洲性猛交xxxx| …日韩人妻无码精品一专区 | 成在线人永久免费视频播放| 毛片免费全部播放无码| 日本视频高清一道一区| 欧美性生交xxxxx久久久| 日韩人妻无码一区二区三区综合 | 天天av天天翘天天综合网色鬼| 999久久久国产精品消防器材| 亚洲国产精品国自产拍电影| 国产免费久久精品99reswag| 国产精品日韩欧美一区二区三区| 中文字幕乱码中文乱码777| 樱花草在线社区www中国中文| 日本久久综合久久鬼色| 人妻体内射精一区二区三四| 午夜精品久久久久久久久久久久| 巨大乳做爰视频在线看| 久久国产高潮流白浆免费观看| 黑人玩弄人妻中文在线| 精品国精品国产自在久国产87| 国产精品白浆在线观看免费| 日本乱人伦aⅴ精品| 亚洲精品久久久久国产| 亚洲一区av在线观看| 18禁勿入午夜网站入口| 夜夜夜夜猛噜噜噜噜噜试看| 国产午夜手机精彩视频| 精品久久久久久久久中文字幕| 日韩欧美亚洲综合久久影院d3| 伊人久久大香线蕉影院| 免费久久人人爽人人爽av| 国产精品色无码av在线观看| 精品免费国偷自产在线视频|