在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Adipolin (C1QTNF12)

In Stock
  • 貨號:
    CSB-EP840280MO
  • 規格:
    ¥2328
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    C1qtnf12
  • Uniprot No.:
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    E.coli
  • 分子量:
    37.0 kDa
  • 表達區域:
    22-308aa
  • 氨基酸序列
    RQELKKSRQLFARVDSPNITTSNREGFPGSVKPPEASGPELSDAHMTWLNFVRRPDDGSSRKRCRGRDKKSRGLSGLPGPPGPPGPPGPPGSPGVGVTPEALLQEFQEILKEATELRFSGLPDTLLPQEPSQRLVVEAFYCRLKGPVLVDKKTLVELQGFQAPTTQGAFLRGSGLSLSLGRFTAPVSAIFQFSASLHVDHSELQGRGRLRTRDMVRVLICIESLCHRHTSLEAVSGLESNSRVFTVQVQGLLHLQSGQYVSVFVDNSSGAVLTIQNTSSFSGMLLGT
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via the PI3K-Akt signaling pathway. Administration lead to reduction of blood glucose. Able to attenuate inflammation in fat tissue.; Acts by activating the Akt signaling in hepatocytes and adipocytes. Not able to increase insulin-stimulated glucose uptake in adipocytes.; Acts by activating the MAP kinase. Increases insulin-stimulated glucose uptake in adipocytes.
  • 基因功能參考文獻:
    1. Loss of a single Ctrp12 allele affects glucose and lipid metabolism. PMID: 27815536
    2. mRNA expression of Fam132a, which encodes a newly identified insulin-sensitizing adipokine, adipolin, is significantly upregulated in the absence of KLF3. PMID: 23633521
    3. These data suggest that obesity states facilitate the cleavage of adipolin presumably through upregulation of furin in adipose tissue. PMID: 23068097
    4. The aim of this study was to demonstrate adipolin expression in human and murine chondrocytes and to elucidate the intracellular mechanism involved in adipolin basal expression PMID: 22736092
    5. Endopeptidase cleavage generates a functionally distinct isoform of C1q/tumor necrosis factor-related protein-12 (CTRP12) with an altered oligomeric state and signaling specificity. PMID: 22942287
    6. CTRP12 as a novel metabolic regulator linking adipose tissue to whole body glucose homeostasis through insulin-dependent and independent mechanisms. PMID: 22275362
    7. Adipolin/C1qdc2/CTRP12 protein functions as an adipokine that improves glucose metabolism PMID: 21849507

    顯示更多

    收起更多

  • 亞細胞定位:
    [Adipolin fC1QTNF12]: Secreted.; [Adipolin gC1QTNF12]: Secreted.
  • 蛋白家族:
    Adipolin/erythroferrone family
  • 組織特異性:
    Widely expressed, with high expression in subcutaneous and epididymal white adipose tissues and brown adipose tissue. Expressed in adipocytes (at protein level).
  • 數據庫鏈接:


主站蜘蛛池模板: 国产亚洲精品久久久999蜜臀| 免费国产黄网站在线观看视频 | 播五月开心婷婷欧美综合| 亚洲人成网站18禁止大| 亚洲最大激情中文字幕| 夜夜夜夜猛噜噜噜噜噜| 无码熟妇人妻av| 国产互换人妻hd| 亚洲日产韩国一二三四区| 波多野av一区二区无码| 中国产xxxxa片在线观看| 中文字幕人妻熟女人妻洋洋| 日本免码va在线看免费| 麻花豆传媒剧国产免费mv观看| 综合亚洲另类欧美久久成人精品| 日韩一本之道一区中文字幕| 亚洲色婷婷婷婷五月基地| 成人午夜福利免费体验区| 人妻少妇精品一区二区三区| 亚洲人亚洲精品成人网站| 亚洲欧美日韩成人一区二区三区| 亚洲不卡一卡2卡三卡4卡5卡| 中文无码日韩欧| 亚欧美无遮挡hd高清在线视频| 成年男人裸j照无遮挡无码| 欧美成人看片一区二三区图文| 漂亮人妻被强中文字幕久久| 成人免费无码av| 免费午夜无码片在线观看影院| 亚洲综合区小说区激情区| 新香蕉少妇视频网站| 搡老熟女老女人一区二区| 日本一二免费不卡区| 国产精品乱码久久久久软件| 国产精品特级毛片一区二区三区 | 亚洲中文字幕无码永久在线| 少妇愉情理伦片丰满丰满午夜| 成 人 a v免费视频在线观看 | 久久午夜福利无码1000合集| 国产97公开成人免费视频在线观看 | 国产成人av大片在线播放|