在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Acyl-CoA-binding protein (Dbi)

Recombinant Mouse Acyl-CoA-binding protein (Dbi)

  • 貨號(hào)：
    CSB-YP006519MO
  • 規(guī)格：
    ￥2208
  • 圖片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

產(chǎn)品詳情

  • 純度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
  • Uniprot No.：
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度：
    Full Length of Mature Protein
  • 來(lái)源：
    Yeast
  • 分子量：
    11.9 kDa
  • 表達(dá)區(qū)域：
    2-87aa
  • 氨基酸序列
    SQAEFDKAAEEVKRLKTQPTDEEMLFIYSHFKQATVGDVNTDRPGLLDLKGKAKWDSWNKLKGTSKESAMKTYVEKVDELKKKYGI
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽：
    N-terminal 6xHis-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.
  • 基因功能參考文獻(xiàn)：
    1. DBI is expressed in stem cells in all neurogenic niches of the postnatal brain. DBI regulates the balance between preserving the stem cell pool and neurogenesis. Specifically, DBI dampens GABA activity in stem cells, thereby sustaining the proproliferative effect of physical exercise and enriched environment. PMID: 28343864
    2. ACBP increases the activity of ceramide synthase 2 (CerS2) by more than 2-fold and CerS3 activity by 7-fold. ACBP binds very-long-chain acyl-CoA esters, which is required for its ability to stimulate CerS activity. PMID: 28320857
    3. Mice with conditional targeting of the Acbp gene in the epidermis recapitulate this phenotype, whereas generation of an artificial epidermal barrier during gland development reverses the phenotype PMID: 26142722
    4. This study demonistrated that a novel role for ACBP in brain lipid metabolism. PMID: 25598214
    5. Acyl-CoA binding protein and epidermal barrier function. [review] PMID: 24080521
    6. ACBP is required for production of VLC-FFA for stratum corneum and for maintaining normal epidermal barrier function PMID: 22829653
    7. It was concluded that acyl-CoA binding protein via aquaporin 3 is necessary for intact urine concentrating ability through efflux over the basolateral membrane of the collecting duct. PMID: 22237802
    8. Diazepam binding inhibitor promotes progenitor proliferation in the postnatal SVZ by reducing GABA signaling. PMID: 22226357
    9. lack of ACBP interferes with the normal metabolic adaptation to weaning and leads to delayed induction of the lipogenic gene program in the liver PMID: 21106527
    10. Acyl-CoA binding protein gene ablation induces pre-implantation embryonic lethality in mice PMID: 20559753
    11. Acute food deprivation reduces expression of diazepam-binding inhibitor in mouse glial cells. PMID: 20219854
    12. the present study revealed a definite existence of DBI in non-neuronal supporting cells in both the central and peripheral nervous systems. PMID: 12002608
    13. PPRE in intron 1 of the ACBP gene is a bona fide PPARgamma-response element. PMID: 12015306
    14. A functionally active recombinant ACBP with amino acid sequence identical to the native protein interacts preferentially with anionic phospholipid-rich, highly curved membranes to facilitate transfer of ACBP-bound ligands. PMID: 12173941
    15. ACBP was the most potent intracellular fatty acyl CoA binding protein in differentially modulating the activity of microsomal ACAT to form cholesteryl esters independent of cholesterol binding/transfer ability PMID: 12518025
    16. Results identify new acyl-CoA binding protein transcripts in human and mouse tissues, generated by alternative first exon usage. PMID: 16055366
    17. Acbp plays a role in triacylglycerol biosynthesis, and that regulation of this process is important for proper hair and skin development and maintenance in the mouse. PMID: 16902415
    18. Endogenously overexpressed DBI impairs hippocampus-dependent learning without anxiety or proconflict behavior. PMID: 17150371

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Endoplasmic reticulum. Golgi apparatus.
  • 蛋白家族：
    ACBP family
  • 數(shù)據(jù)庫(kù)鏈接：


主站蜘蛛池模板： 国产欧美日韩综合精品二区| 亚洲中文字幕人成乱码| 丰满的少妇邻居中文bd| 成人伊人青草久久综合网| 丰满熟女人妻中文字幕免费| 风流老熟女一区二区三区| 无码av动漫精品一区二区免费| 99久久国产综合精品1| 国产乱人伦中文无无码视频试看| 国产又黄又猛又粗又爽的a片动漫| 免费无码成人片| 亚洲性夜夜综合久久7777| 国产精品久久国产精麻豆99网站| 国产精品视频一区二区噜噜| 久久久亚洲欧洲日产国产成人无码 | 国产精品99爱免费视频| 亚洲第一无码xxxxxx| 8天堂资源在线| 国产在线精品无码不卡手机免费 | 亚洲337少妇裸体艺术| 玩肥熟老妇bbw视频| 久久精品aⅴ无码中文字字幕 | 国产影片中文字幕| 久久青青草原国产最新片完整 | 国产精品人成在线播放新网站| 色老99久久精品偷偷鲁| 国产精品盗摄!偷窥盗摄| 国产欧美日韩专区发布| 欧美性狂猛xxxxx深喉| 亚洲精品无码鲁网午夜| 中文字幕亚洲无线码在线一区| 又爽又黄无遮拦成人网站| 激情综合五月丁香亚洲| 苍井空一区二区波多野结衣av| 精品人妻一区二区三区四区| 国产亚洲精品福利视频在线观看| 日韩v亚洲v欧美v精品综合| 特黄大片又粗又大又暴| 国产亚洲综合区成人国产| 色视频综合无码一区二区三区| 国产丝袜一区视频在线观看 |