在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Acyl-CoA-binding protein (Dbi)

Recombinant Mouse Acyl-CoA-binding protein (Dbi)

  • 中文名稱：
    Recombinant Mouse Acyl-CoA-binding protein(Dbi)
  • 貨號：
    CSB-YP006519MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Acyl-CoA-binding protein(Dbi)
  • 貨號：
    CSB-EP006519MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Acyl-CoA-binding protein(Dbi)
  • 貨號：
    CSB-BP006519MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Acyl-CoA-binding protein(Dbi)
  • 貨號：
    CSB-MP006519MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    DbiAcyl-CoA-binding protein; ACBP; Diazepam-binding inhibitor; DBI; Endozepine; EP
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-87
  • 氨基酸序列
    SQAEFDKAA EEVKRLKTQP TDEEMLFIYS HFKQATVGDV NTDRPGLLDL KGKAKWDSWN KLKGTSKESA MKTYVEKVDE LKKKYGI
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.
  • 基因功能參考文獻：
    1. DBI is expressed in stem cells in all neurogenic niches of the postnatal brain. DBI regulates the balance between preserving the stem cell pool and neurogenesis. Specifically, DBI dampens GABA activity in stem cells, thereby sustaining the proproliferative effect of physical exercise and enriched environment. PMID: 28343864
    2. ACBP increases the activity of ceramide synthase 2 (CerS2) by more than 2-fold and CerS3 activity by 7-fold. ACBP binds very-long-chain acyl-CoA esters, which is required for its ability to stimulate CerS activity. PMID: 28320857
    3. Mice with conditional targeting of the Acbp gene in the epidermis recapitulate this phenotype, whereas generation of an artificial epidermal barrier during gland development reverses the phenotype PMID: 26142722
    4. This study demonistrated that a novel role for ACBP in brain lipid metabolism. PMID: 25598214
    5. Acyl-CoA binding protein and epidermal barrier function. [review] PMID: 24080521
    6. ACBP is required for production of VLC-FFA for stratum corneum and for maintaining normal epidermal barrier function PMID: 22829653
    7. It was concluded that acyl-CoA binding protein via aquaporin 3 is necessary for intact urine concentrating ability through efflux over the basolateral membrane of the collecting duct. PMID: 22237802
    8. Diazepam binding inhibitor promotes progenitor proliferation in the postnatal SVZ by reducing GABA signaling. PMID: 22226357
    9. lack of ACBP interferes with the normal metabolic adaptation to weaning and leads to delayed induction of the lipogenic gene program in the liver PMID: 21106527
    10. Acyl-CoA binding protein gene ablation induces pre-implantation embryonic lethality in mice PMID: 20559753
    11. Acute food deprivation reduces expression of diazepam-binding inhibitor in mouse glial cells. PMID: 20219854
    12. the present study revealed a definite existence of DBI in non-neuronal supporting cells in both the central and peripheral nervous systems. PMID: 12002608
    13. PPRE in intron 1 of the ACBP gene is a bona fide PPARgamma-response element. PMID: 12015306
    14. A functionally active recombinant ACBP with amino acid sequence identical to the native protein interacts preferentially with anionic phospholipid-rich, highly curved membranes to facilitate transfer of ACBP-bound ligands. PMID: 12173941
    15. ACBP was the most potent intracellular fatty acyl CoA binding protein in differentially modulating the activity of microsomal ACAT to form cholesteryl esters independent of cholesterol binding/transfer ability PMID: 12518025
    16. Results identify new acyl-CoA binding protein transcripts in human and mouse tissues, generated by alternative first exon usage. PMID: 16055366
    17. Acbp plays a role in triacylglycerol biosynthesis, and that regulation of this process is important for proper hair and skin development and maintenance in the mouse. PMID: 16902415
    18. Endogenously overexpressed DBI impairs hippocampus-dependent learning without anxiety or proconflict behavior. PMID: 17150371

    顯示更多

    收起更多

  • 亞細胞定位：
    Endoplasmic reticulum. Golgi apparatus.
  • 蛋白家族：
    ACBP family
  • 數據庫鏈接：


主站蜘蛛池模板： 精品国产乱码久久久久久1区2区| 国产精品偷伦视频观看免费| 国产特级毛片aaaaaa高清| 亚洲第一av网站| 在线观看片免费人成视频播放| 综合久久—本道中文字幕| 在线观看无码av网址| 无码aⅴ在线观看| 男人扒开女人内裤强吻桶进去 | 欧美成年网站色a| 成熟人妻av无码专区| 综合图片亚洲综合网站| 波多野结衣中文字幕久久| 夜夜澡人摸人人添人人看| 国产精品久久久天天影视香蕉| av无码免费一区二区三区| 97在线视频人妻无码| 激情五月色综合国产精品| 日韩精品一区二区av在线| 国产成人一区二区不卡免费视频| 疯狂做受xxxx高潮视频免费| 久久人妻无码中文字幕第一| 欧美自拍亚洲综合丝袜| 亚洲精品无播放器在线播放| 国产欧美综合一区二区三区| 亚洲另类无码专区丝袜| 亚洲开心婷婷中文字幕| 国产欧美va欧美va香蕉在线| 亚洲成在人线av| 亚洲精品无码人妻无码| 四虎精品免费永久免费视频| 天堂www中文在线资源| 亚洲精品一区二区三区在线观看| 国产亚洲熟妇综合视频| 久久国产色av免费观看| 欧美最猛性xxxxx免费| 国产成人精品久久久久精品日日| 精品国产一区二区av麻豆| 久久国产成人午夜av影院| 亚洲中文字幕无码永久| 色欲综合久久中文字幕网|