Recombinant Location of vulva defective 1 (lov-1), partial
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中文名稱:秀麗隱桿線蟲lov-1重組蛋白
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貨號:CSB-EP600254CXY-B
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說明書:
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規格:
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來源:E.coli
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共軛:Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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其他:
產品詳情
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純度:>85% (SDS-PAGE)
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基因名:lov-1
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Uniprot No.:
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別名:lov-1; pkd-1; ZK945.9/ZK945.10; Location of vulva defective 1; Polycystic kidney disease 1 protein homolog; Polycystin-1
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種屬:Caenorhabditis elegans
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蛋白長度:Partial
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蛋白標簽:Tag?type?will?be?determined?during?the?manufacturing?process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially. -
產品提供形式:Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand. -
復溶:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
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儲存條件:Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
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保質期:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
貨期:Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
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注意事項:Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Datasheet :Please contact us to get it.
靶點詳情
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功能:Required for two aspects of male mating behavior: response to hermaphrodite contact and vulva location. Acts in the same pathway as pkd-2 and atp-2 in response behavior. May be required for ciliary targeting of pkd-2.
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基因功能參考文獻:
- expressed in male-specific neurons, required for mating PMID: 26702651
- These data reveal that the STAM-Hrs complex, which down-regulates ligand-activated growth factor receptors from the cell surface of yeast and mammalian cells, also regulates the localization and signaling of a ciliary PC1 receptor-TRPP2 complex. PMID: 17581863
- lov-1 is required for two male sensory behaviors: response and vulva location. It is a close homolog of human PKD1 and is localized in the same neurons as worm PKD-2, suggesting a common pathway. PMID: 10517638
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亞細胞定位:Membrane; Multi-pass membrane protein. Cell projection, cilium. Note=localizes to both the ciliary base and cilium proper.
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蛋白家族:Polycystin family
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組織特異性:Exclusively expressed in a subset of three categories of adult male sensory neurons: ray neurons, hook neurons and head cephalic (CEM) neurons.
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