在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant JC polyomavirus Agnoprotein, partial

Recombinant JC polyomavirus Agnoprotein, partial

  • 中文名稱：
    Recombinant JC polyomavirus Agnoprotein,partial
  • 貨號：
    CSB-YP355945JAK
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant JC polyomavirus Agnoprotein,partial
  • 貨號：
    CSB-EP355945JAK
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant JC polyomavirus Agnoprotein,partial
  • 貨號：
    CSB-EP355945JAK-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant JC polyomavirus Agnoprotein,partial
  • 貨號：
    CSB-BP355945JAK
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant JC polyomavirus Agnoprotein,partial
  • 貨號：
    CSB-MP355945JAK
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    N/A
  • Uniprot No.：
  • 別名：
    Agnoprotein; Agno
  • 種屬：
    JC polyomavirus (JCPyV) (JCV)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Alters the structure of the nuclear envelope by interacting with host CBX5 and disrupting CBX5 association with LBR. Involved in the perinuclear-nuclear localization of the capsid protein VP1 during virion assembly and maturation. Plays an important role in the release of progeny virions from infected cells and in viral propagation, probably by acting as a viral ionic channel in the host plasma membrane. Allows influx of extracellular calcium ions in the host cell. May contribute to viral genome transcription and translation of viral late proteins.
  • 基因功能參考文獻：
    1. the resolution of the 3D structure of full-length JCV agnoprotein by NMR, which not only confirmed the existence of the previously reported major alpha-helix domain at the same position but also revealed the presence of an additional minor alpha-helix region spanning amino acid residues Leu6 to lys13. The remaining regions of the protein adopt an intrinsically unstructured conformation. PMID: 28295503
    2. Amino acid residues (Lys22, Lys23, Phe31, Glu34, and Asp38) located either on or adjacent to the hydrophilic surface of the major alpha-helix domain of Agno play critical roles in release. PMID: 28722139
    3. L29A and L36A mutations of agnoprotein exhibited a significant negative effect on both protein stability and viral replication PMID: 24672035
    4. Authors showed that a Leu/Ile/Phe-rich domain, (spanning aa 28-39) within alpha-helix is indispensable for dimer/oligomer formation and stable expression of the protein and that residues 34-36 are involved in regulation of viral transcripts splicing. PMID: 23747198
    5. Agnoprotein affects virion morphology and the virions of the agnoprotein deletion mutant are irregularly shaped. PMID: 22708997
    6. JC virus agnoprotein enhances large T antigen binding to the origin of viral DNA replication. PMID: 22840425
    7. The novel tropism for infection of cortical pyramidal neurons in JC virus encephalopathy may be associated with an JC virus agnoprotein deletion mutation. PMID: 22536439
    8. Agnoprotein forms homodimer/oligomer complexes and these are important for its function during viral propagation. PMID: 21920573
    9. Infection by agnoprotein-negative mutants of both polyomavirus JC and SV40 virus results in the release of virions that are mostly deficient in DNA content. PMID: 21609431
    10. we demonstrate that agnoprotein possesses properties commonly associated with viroporins PMID: 20300659
    11. These observations provide the first evidence for the possible involvement of agnoprotein in a series of biological events that may contribute to the pathological features seen in progressive multifocal leukoencephalopathy lesions. PMID: 17989177

    顯示更多

    收起更多

  • 亞細胞定位：
    Host cytoplasm. Host nucleus membrane; Single-pass type II membrane protein. Host rough endoplasmic reticulum membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Polyomavirus agnoprotein family
  • 數據庫鏈接：

    KEGG: vg:1489519



主站蜘蛛池模板： 草草网站影院白丝内射| 亲嘴扒胸摸屁股激烈网站 | 性欧美大战久久久久久久| 国产成人a亚洲精v品无码 | 樱花草在线社区www中国中文 | √最新版天堂资源网在线| 日本无翼乌邪恶大全彩h | 怡红院av亚洲一区二区三区h| 无码中文字幕日韩专区视频| yy6080久久伦理一区二区| 亚洲欧美日韩视频高清专区 | 农村乱人伦一区二区| 国产精品久久一区二区三区| 中国精品少妇hd| 青青草无码免费一二三区| 亚洲中文字幕无码卡通动漫野外| 男男又爽又黄又无遮挡网站| 国内女人喷潮完整视频| 国内精品久久久人妻中文字幕| 日本熟妇色一本在线观看| 99久久国产成人免费网站| 国产综合色在线精品| 99久久国产热无码精品免费| 免费人成视频在线观看视频| 久久三级中文欧大战字幕| 伊人av超碰伊人久久久| 色噜噜狠狠狠综合曰曰曰| 中文字幕丰满孑伦无码精品| 国产成人精品永久免费视频| 欧美阿v高清资源在线| 亚洲精品一区二区三区四区乱码| 亚洲人成色777777精品音频| 久久天堂av综合合色蜜桃网| 69国产成人精品午夜福中文| 欧美另类videossexo高潮| 精品人体无码一区二区三区| 日本欧美一区二区免费视频| 欧美做受又硬又粗又大视频| 97人妻精品一区二区三区| 夜夜精品无码一区二区三区| 国产亚洲精aa在线观看|