在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human immunodeficiency virus type 1 group O Protein Rev (rev)

Recombinant Human immunodeficiency virus type 1 group O Protein Rev (rev)

  • 中文名稱：
    Recombinant Human immunodeficiency virus type 1 group O Protein Rev(rev)
  • 貨號：
    CSB-YP366250HLS
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human immunodeficiency virus type 1 group O Protein Rev(rev)
  • 貨號：
    CSB-EP366250HLS
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human immunodeficiency virus type 1 group O Protein Rev(rev)
  • 貨號：
    CSB-EP366250HLS-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human immunodeficiency virus type 1 group O Protein Rev(rev)
  • 貨號：
    CSB-BP366250HLS
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human immunodeficiency virus type 1 group O Protein Rev(rev)
  • 貨號：
    CSB-MP366250HLS
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    rev
  • Uniprot No.：
  • 別名：
    rev; Protein Rev; ART/TRS; Anti-repression transactivator; Regulator of expression of viral proteins
  • 種屬：
    Human immunodeficiency virus type 1 group O (isolate ANT70) (HIV-1)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-102
  • 氨基酸序列
    MAGRSEDDQL LQAIQIIKIL YQSNPQPSPR GSRNARKNRR RRWRRRQAQV DTLAARVLAT VVHGPQNNNI VDLPPLEQLS IRDPEGDQLS EAWTVDPRAE DN
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells. These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts). This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs. Rev itself is translated from a fully spliced mRNA that readily exits the nucleus. Rev's nuclear localization signal (NLS) binds directly to KPNB1/Importin beta-1 without previous binding to KPNA1/Importin alpha-1. KPNB1 binds to the GDP bound form of RAN (Ran-GDP) and targets Rev to the nucleus. In the nucleus, the conversion from Ran-GDP to Ran-GTP dissociates Rev from KPNB1 and allows Rev's binding to the RRE in viral pre-mRNAs. Rev multimerization on the RRE via cooperative assembly exposes its nuclear export signal (NES) to the surface. Rev can then form a complex with XPO1/CRM1 and Ran-GTP, leading to nuclear export of the complex. Conversion from Ran-GTP to Ran-GDP mediates dissociation of the Rev/RRE/XPO1/RAN complex, so that Rev can return to the nucleus for a subsequent round of export. Beside KPNB1, also seems to interact with TNPO1/Transportin-1, RANBP5/IPO5 and IPO7/RANBP7 for nuclear import. The nucleoporin-like HRB/RIP is an essential cofactor that probably indirectly interacts with Rev to release HIV RNAs from the perinuclear region to the cytoplasm.
  • 亞細胞定位：
    Host nucleus, host nucleolus. Host cytoplasm.
  • 蛋白家族：
    HIV-1 REV protein family


主站蜘蛛池模板： 国产av久久人人澡人人爱| 男男啪啪激烈高潮cc漫画免费| 亚洲一区二区观看播放| 丝袜高跟麻麻浓精受孕人妻| 人妻无码vs中文字幕久久av爆 | 婷婷五月开心亚洲综合在线| 国产精品av一区二区三区不卡蜜| 乱中年女人伦av三区| 18禁裸乳无遮挡啪啪无码免费| 白嫩无码人妻丰满熟妇啪啪区百度 | 亚洲精品卡2卡3卡4卡5卡区| 2020久久超碰国产精品最新 | 亚洲一卡一卡二新区无人区| 人妻少妇偷人无码视频| 131美女爱做视频免费| 国产亚洲精品美女久久久久| 国产亚洲精品ae86| 国产农村乱子伦精品视频| 真正免费毛片在线播放| 激情五月综合色婷婷一区二区| 99在线精品视频在线观看| 人人妻人人爽日日人人| 五月天激情国产综合婷婷婷| 成人av片无码免费网站| 一本久道久久综合久久爱| 国产精品9999久久久久| 中国亚洲女人69内射少妇| 久久久久久亚洲精品成人| 久久久久欧美精品观看| 亚洲欧美精品午睡沙发| 中文字幕精品一区二区精品| 日日摸夜夜摸狠狠摸婷婷| 性欧美老妇另类xxxx| 女人18片毛片60分钟| 精品亚洲国产成人a片app| 亚洲欧洲日产国码无码网站| 女人扒开屁股桶爽30分钟| 色综合久久久无码中文字幕| 2019精品国自产拍在线不卡| 国产96在线 | 亚洲| 极品嫩模高潮叫床|