在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human coronavirus 229E Spike glycoprotein (S), partial

In Stock
  • 貨號:
    CSB-EP321366HIT
  • 規格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    E2 Peplomer protein
  • 種屬:
    Human coronavirus 229E (HCoV-229E)
  • 蛋白長度:
    Partial
  • 來源:
    E.coli
  • 分子量:
    17.2 kDa
  • 表達區域:
    785-873aa
  • 氨基酸序列
    DVLQENQKILAASFNKAMTNIVDAFTGVNDAITQTSQALQTVATALNKIQDVVNQQGNSLNHLTSQLRQNFQAISSSIQAIYDRLDTIQ
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged and C-terminal Myc-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    S1 region attaches the virion to the cell membrane by interacting with host ANPEP/aminopeptidase N, initiating the infection. Binding to the receptor probably induces conformational changes in the S glycoprotein unmasking the fusion peptide of S2 region and activating membranes fusion. S2 region belongs to the class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.
  • 基因功能參考文獻:
    1. Two amino acid substitutions (R642M and N714K) in the S protein of HCoV-229E clinical isolates altered their sensitivity to a cathepsin L inhibitors and their tropism towards endosomes. PMID: 27733646
    2. The highly homologous C-terminal parts of the NL63-S1 subunits in conjunction with distinct amino acids in the central regions of these proteins confer recognition of ACE2 and CD13, respectively. PMID: 16912312
  • 亞細胞定位:
    Virion membrane; Single-pass type I membrane protein. Host endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    Alphacoronaviruses spike protein family
  • 數據庫鏈接:

    KEGG: vg:918758



主站蜘蛛池模板: 国精品99久9在线 | 免费| 鲁丝片一区二区三区毛片| 黑人巨大无码中文字幕无码| 曰批全过程免费视频观看软件潮喷| 久久久国产乱子伦精品作者| 亚洲日韩中文无码久久| 性夜影院午夜看片| 亚洲五月综合缴情在线观看| 免费人成无码大片在线观看 | 日躁夜躁狠狠躁2001| 秋秋影视午夜福利高清| 精品乱码一区二区三四五区| 国产精品老热丝在线观看| 亚洲精品亚洲人成在线观看| 国产精品一区在线蜜臀| 无码乱人伦一区二区亚洲| 夜夜未满十八勿进的爽爽影院| 少妇仑乱a毛片无码| 亚洲va综合va国产产va中| 人妻少妇无码精品视频区| 精品国产免费一区二区三区 | 精品国内自产拍在线播放观看| 亚洲精品成人av观看| 国产午夜福利精品久久2021| 50岁退休熟女露脸高潮| 日韩高清成片免费视频| 色yeye香蕉凹凸视频在线观看| 亚洲午夜福利在线观看| 国模无码人体一区二区| 中文字幕人妻第一区| 熟妇人妻系列aⅴ无码专区友真希| 国产成人麻豆精品午夜福利在线| 亚洲日韩va在线视频| 国产成人无码一二三区视频| 久久亚洲私人国产精品va| 国内永久福利在线视频图片| 精品国产一区二区三区四区| 国产无遮挡又黄又爽又色| 久久久久久国产精品mv| 好男人社区www在线观看| 中字幕人妻一区二区三区|