Recombinant Human Zinc finger protein ZXDC (ZXDC), partial

中文名稱：

人ZXDC重組蛋白
貨號(hào)：

CSB-YP648494HU
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱：

人ZXDC重組蛋白
貨號(hào)：

CSB-EP648494HU
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱：

人ZXDC重組蛋白
貨號(hào)：

CSB-EP648494HU-B
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人ZXDC重組蛋白
貨號(hào)：

CSB-BP648494HU
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱：

人ZXDC重組蛋白
貨號(hào)：

CSB-MP648494HU
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

ZXDC
Uniprot No.：

Q2QGD7
別名：

ZXDC; ZXDL; Zinc finger protein ZXDC; ZXD-like zinc finger protein
種屬：

Homo sapiens (Human)
蛋白長(zhǎng)度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes.
基因功能參考文獻(xiàn)：
1. Data show that ZXDC1 is a regulator in the process of myeloid function and that ZXDC1 is responsible for Ccl2 gene de-repression by BCL6. PMID: 23954399
2. Role of ZXD proteins in regulating MHC II transcription. PMID: 19777325
3. ZXDC is an important regulator of both MHC class I and class II transcription PMID: 16600381
4. ZXDA and ZXDC form an important regulatory complex for MHC II gene transcription. PMID: 17493635
5. study found sumoylation does not appear to disrupt or modulate interaction of ZXDC with binding partners; sumoylation of ZXDC is required for full activity of transcriptional activation domain; study suggests sumoylation is an important regulator of ZXDC PMID: 17696781
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亞細(xì)胞定位：

Nucleus.
蛋白家族：

ZXD family
組織特異性：

Expressed at high levels in heart, kidney, liver and testis, at moderate levels in brain and stomach, and at low levels in lung, muscle, placenta, small intestine and spleen.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 28160

OMIM: 615746

KEGG: hsa:79364

STRING: 9606.ENSP00000374359

UniGene: Hs.440049