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ZXDC Antibody, Biotin conjugated

  • 中文名稱:
    ZXDC兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA648494LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) ZXDC Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    ZXDC
  • 別名:
    ZXDC antibody; ZXDL antibody; Zinc finger protein ZXDC antibody; ZXD-like zinc finger protein antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Zinc finger protein ZXDC protein (139-416AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes.
  • 基因功能參考文獻:
    1. Data show that ZXDC1 is a regulator in the process of myeloid function and that ZXDC1 is responsible for Ccl2 gene de-repression by BCL6. PMID: 23954399
    2. Role of ZXD proteins in regulating MHC II transcription. PMID: 19777325
    3. ZXDC is an important regulator of both MHC class I and class II transcription PMID: 16600381
    4. ZXDA and ZXDC form an important regulatory complex for MHC II gene transcription. PMID: 17493635
    5. study found sumoylation does not appear to disrupt or modulate interaction of ZXDC with binding partners; sumoylation of ZXDC is required for full activity of transcriptional activation domain; study suggests sumoylation is an important regulator of ZXDC PMID: 17696781

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  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    ZXD family
  • 組織特異性:
    Expressed at high levels in heart, kidney, liver and testis, at moderate levels in brain and stomach, and at low levels in lung, muscle, placenta, small intestine and spleen.
  • 數據庫鏈接:

    HGNC: 28160

    OMIM: 615746

    KEGG: hsa:79364

    STRING: 9606.ENSP00000374359

    UniGene: Hs.440049



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