在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Vacuolar protein sorting-associated protein 53 homolog (VPS53)

  • 中文名稱:
    人VPS53重組蛋白
  • 貨號:
    CSB-YP726098HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人VPS53重組蛋白
  • 貨號:
    CSB-EP726098HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人VPS53重組蛋白
  • 貨號:
    CSB-EP726098HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人VPS53重組蛋白
  • 貨號:
    CSB-BP726098HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人VPS53重組蛋白
  • 貨號:
    CSB-MP726098HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    VPS53
  • Uniprot No.:
  • 別名:
    FLJ10979; FLJ41112; FLJ61757; HCCS1; hVps53L; MGC39512; pp13624; Vacuolar protein sorting 53 (yeast); Vacuolar protein sorting 53; Vacuolar protein sorting 53 homolog (S. cerevisiae); Vacuolar protein sorting-associated protein 53 homolog; VPS53; VPS53_HUMAN
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-699
  • 氨基酸序列
    MMEEEELEFV EELEAVLQLT PEVQLAIEQV FPSQDPLDRA DFNAVEYINT LFPTEQSLAN IDEVVNKIRL KIRRLDDNIR TVVRGQTNVG QDGRQALEEA QKAIQQLFGK IKDIKDKAEK SEQMVKEITR DIKQLDHAKR HLTTSITTLN HLHMLAGGVD SLEAMTRRRQ YGEVANLLQG VMNVLEHFHK YMGIPQIRQL SERVKAAQTE LGQQILADFE EAFPSQGTKR PGGPSNVLRD ACLVANILDP RIKQEIIKKF IKQHLSEYLV LFQENQDVAW LDKIDRRYAW IKRQLVDYEE KYGRMFPREW CMAERIAVEF CHVTRAELAK IMRTRAKEIE VKLLLFAIQR TTNFEGFLAK RFSGCTLTDG TLKKLESPPP STNPFLEDEP TPEMEELATE KGDLDQPKKP KAPDNPFHGI VSKCFEPHLY VYIESQDKNL GELIDRFVAD FKAQGPPKPN TDEGGAVLPS CADLFVYYKK CMVQCSQLST GEPMIALTTI FQKYLREYAW KILSGNLPKT TTSSGGLTIS SLLKEKEGSE VAKFTLEELC LICNILSTAE YCLATTQQLE EKLKEKVDVS LIERINLTGE MDTFSTVISS SIQLLVQDLD AACDPALTAM SKMQWQNVEH VGDQSPYVTS VILHIKQNVP IIRDNLASTR KYFTQFCVKF ANSFIPKFIT HLFKCKPISM VGAEQVRWT
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane.
  • 基因功能參考文獻:
    1. sensitivity of serum Hepatocellular carcinoma suppressor 1 (HCCS1) promoter methylation for discriminating patients with hepatocellular carcinoma from chronic hepatitis B was 62.5% PMID: 28189396
    2. Golgi-associated retrograde protein orchestrates retrograde transport from endosomes to the trans-Golgi network by promoting vesicle tethering and assembly of SNARE complexes in consecutive, independent steps.[Golgi associated retrograde protein] PMID: 19620288
    3. Golgi associated retrograde protein complex, consisting of the Vps52, Vps53, and Vps54 proteins, shows significant conservation between various species but diversification and specialization result in important differences in human cells. PMID: 15878329
    4. Data show that transcription of the putative tumor suppressor gene HCCS1 requires binding of ETS-2 to its consensus near the transcription start site; observations provide insight into the mechanistic aspects of HCCS1 transcription regulation PMID: 16953216
    5. Amphipathic tail-anchoring peptide (ATAP) targets specifically to mitochondria, and induces caspase-dependent apoptosis that does not require Bax or Bak. PMID: 17666431
    6. Missorting of cathepsin D in GARP-depleted cells results from accumulation of recycling MPRs in a population of light, small vesicles downstream of endosomes. PMID: 18367545

    顯示更多

    收起更多

  • 相關疾病:
    Pontocerebellar hypoplasia 2E (PCH2E)
  • 亞細胞定位:
    Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Recycling endosome.
  • 蛋白家族:
    VPS53 family
  • 數據庫鏈接:

    HGNC: 25608

    OMIM: 615850

    KEGG: hsa:55275

    STRING: 9606.ENSP00000401435

    UniGene: Hs.461819



主站蜘蛛池模板: 丰满妇女强制高潮18xxxx| 国产粉嫩嫩00在线正在播放| 精品国产一区二区三区av色诱| 成人午夜无码精品免费看| 久久不见久久见免费视频下载| 亚洲线精品一区二区三区| 无套内射在线无码播放| 四虎成人精品无码永久在线| 性中国妓女毛茸茸视频| 丰满少妇呻吟高潮经历| 国产一区二区三区乱码在线观看| 乱码丰满人妻一二三区| 国产免费人成视频在线播放播 | 少妇被又大又粗猛烈进出视频| 激情av无码后入| 人妻av中文系列| 国产精品香港三级国产av| 亚洲色在线无码国产精品| 国产欧美日本亚洲精品一5区| 亚洲精品99久久久久中文字幕| 亚洲成a人片在线观看中文| 国产在线观看精品一区二区三区| 在线va无卡无码高清| 免费网站观看www在线观看| 熟妇人妻av无码一区二区三区| 日韩精品无码一本二本三本| 好吊射视频988gaocom| 国产精品久久久久影院老司| 色五月五月丁香亚洲综合网| 国产成人av国语在线观看| 国产美女久久久亚洲综合| 久久av无码精品人妻系列| 午夜影视啪啪免费体验区入口| 欧美日韩人成视频在线播放| 色88久久久久高潮综合影院| 久久久精品国产sm最大网站| 成在人线av无码免费高潮喷水 | 男人女人做爽爽18禁网站| 中国亚洲女人69内射少妇| 成在人线av无码免费高潮水老板 | 国产黄大片在线观看画质优化|