在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Unconventional myosin-XVIIIb (MYO18B), partial

  • 中文名稱:
    人MYO18B重組蛋白
  • 貨號:
    CSB-YP815545HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人MYO18B重組蛋白
  • 貨號:
    CSB-EP815545HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人MYO18B重組蛋白
  • 貨號:
    CSB-EP815545HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人MYO18B重組蛋白
  • 貨號:
    CSB-BP815545HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人MYO18B重組蛋白
  • 貨號:
    CSB-MP815545HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    MYO18B
  • Uniprot No.:
  • 別名:
    BK125H2.1; DKFZp434C2422; DKFZp779C1668; MY18B_HUMAN; MYO18B; myosin 18B ; myosin XVIIIB; Myosin-XVIIIb
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth.
  • 基因功能參考文獻:
    1. Full loss of myo18b function results in a complete lack of sarcomeric structure, revealing a highly surprising and essential role for myo18b in sarcomere assembly. Importantly, scattered thin and thick filaments assemble throughout the sarcoplasm. These observations suggest a novel model of sarcomere assembly where Myo18b coordinates the integration of preformed thick and thin filaments into the sarcomere PMID: 28104788
    2. Deficiency of MYO18B is linked to a novel developmental disorder which combines KFA with myopathy. PMID: 25748484
    3. No associations were found between rs133885 in myosin-18B and mathematical abilities among individuals with dyslexia or in the general population. PMID: 25778778
    4. A common MYO18B variant is associated with mathematical disability in children with dyslexia and with intraparietal sulcus variability in neurotypical adults. PMID: 23423138
    5. candidate tumor suppressor gene at chromosome 22q12.1, deleted, mutated, and methylated in human lung cancer PMID: 12209013
    6. Human MYO18B, a novel unconventional myosin heavy chain expressed in striated muscles moves into the myonuclei upon differentiation PMID: 12547197
    7. MYO18B alterations, including both epigenetic and genetic alterations, play an important role in ovarian carcinogenesis PMID: 15305387
    8. Proteasome dysfunction by a proteasome inhibitor or siRNA-mediated knock-down of Sug1 caused the up-regulation of MYO18B protein and MYO18B was polyubiquitinated in vivo. PMID: 16499872
    9. The restored expression of MYO18B may be a useful therapeutic strategy for the treatment of locally advanced Malignant pleural mesothelioma(MPM)in humans. PMID: 17294804

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Klippel-Feil syndrome 4, autosomal recessive, with nemaline myopathy and facial dysmorphism (KFS4)
  • 亞細胞定位:
    Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere. Note=Punctate pattern in undifferentiated myoblasts. Nuclear, on primary cardiomyocytes and adult muscle. A partial sarcomeric location was found in some cardiomyocytes.
  • 蛋白家族:
    TRAFAC class myosin-kinesin ATPase superfamily, Myosin family
  • 組織特異性:
    Selectively expressed in cardiac and skeletal muscles. Weakly expressed in testis, pancreas, placenta, prostate, lung and thymus.
  • 數據庫鏈接:

    HGNC: 18150

    OMIM: 607295

    KEGG: hsa:84700

    STRING: 9606.ENSP00000334563

    UniGene: Hs.417959



主站蜘蛛池模板: 亚洲区欧美区综合区自拍区| 亚洲狠狠婷婷综合久久| 国产乱国产乱老熟300部视频| 欧亚精品一区三区免费| 人妻少妇无码精品专区| 国产精品免费久久久久电影| 日韩欧美亚洲综合久久| 亚洲色无码专区在线观看精品| 看国产一毛片在线看手机看| 亚洲精品偷拍影视在线观看| 亚洲第一成人网站| 特级无码毛片免费视频尤物| 一本精品99久久精品77| av一区二区国产在线视频| 国产成人精品日本亚洲专区61| 国产suv精品一区二区6| 亚洲国产成人超a在线播放| 国产欧美日韩另类精彩视频| 东京热无码av一区二区| 肉体裸交丰满丰满少妇在线观看| 337p日本大胆欧久久| 亚洲影院丰满少妇中文字幕无码| 最新亚洲人成网站在线观看| 欧美网站免费观看在线| 熟女丝袜潮喷内裤视频网站| 精品国产av一区二区三区| 成人区人妻精品一区二区不卡视频| 天堂网www天堂在线资源| 国内自拍久久久久影院| 久久婷婷国产综合精品| 日韩乱码人妻无码系列中文字幕| 亚洲中文字幕无码天然素人| 一本加勒比hezyo无码人妻| 色偷偷88888欧美精品久久久 | 欧美特大特白屁股ass| 久在线观看福利视频| 99re6热视频这里只精品首页 | 国产熟妇另类久久久久| 男女野外做爰全过程69影院| 亚洲国产成人精品无码区蜜柚| 国产成人精品一区二区三区|