在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Unconventional myosin-XVIIIb (MYO18B), partial

  • 中文名稱:
    人MYO18B重組蛋白
  • 貨號:
    CSB-YP815545HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人MYO18B重組蛋白
  • 貨號:
    CSB-EP815545HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人MYO18B重組蛋白
  • 貨號:
    CSB-EP815545HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人MYO18B重組蛋白
  • 貨號:
    CSB-BP815545HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人MYO18B重組蛋白
  • 貨號:
    CSB-MP815545HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    MYO18B
  • Uniprot No.:
  • 別名:
    BK125H2.1; DKFZp434C2422; DKFZp779C1668; MY18B_HUMAN; MYO18B; myosin 18B ; myosin XVIIIB; Myosin-XVIIIb
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth.
  • 基因功能參考文獻:
    1. Full loss of myo18b function results in a complete lack of sarcomeric structure, revealing a highly surprising and essential role for myo18b in sarcomere assembly. Importantly, scattered thin and thick filaments assemble throughout the sarcoplasm. These observations suggest a novel model of sarcomere assembly where Myo18b coordinates the integration of preformed thick and thin filaments into the sarcomere PMID: 28104788
    2. Deficiency of MYO18B is linked to a novel developmental disorder which combines KFA with myopathy. PMID: 25748484
    3. No associations were found between rs133885 in myosin-18B and mathematical abilities among individuals with dyslexia or in the general population. PMID: 25778778
    4. A common MYO18B variant is associated with mathematical disability in children with dyslexia and with intraparietal sulcus variability in neurotypical adults. PMID: 23423138
    5. candidate tumor suppressor gene at chromosome 22q12.1, deleted, mutated, and methylated in human lung cancer PMID: 12209013
    6. Human MYO18B, a novel unconventional myosin heavy chain expressed in striated muscles moves into the myonuclei upon differentiation PMID: 12547197
    7. MYO18B alterations, including both epigenetic and genetic alterations, play an important role in ovarian carcinogenesis PMID: 15305387
    8. Proteasome dysfunction by a proteasome inhibitor or siRNA-mediated knock-down of Sug1 caused the up-regulation of MYO18B protein and MYO18B was polyubiquitinated in vivo. PMID: 16499872
    9. The restored expression of MYO18B may be a useful therapeutic strategy for the treatment of locally advanced Malignant pleural mesothelioma(MPM)in humans. PMID: 17294804

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Klippel-Feil syndrome 4, autosomal recessive, with nemaline myopathy and facial dysmorphism (KFS4)
  • 亞細胞定位:
    Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere. Note=Punctate pattern in undifferentiated myoblasts. Nuclear, on primary cardiomyocytes and adult muscle. A partial sarcomeric location was found in some cardiomyocytes.
  • 蛋白家族:
    TRAFAC class myosin-kinesin ATPase superfamily, Myosin family
  • 組織特異性:
    Selectively expressed in cardiac and skeletal muscles. Weakly expressed in testis, pancreas, placenta, prostate, lung and thymus.
  • 數據庫鏈接:

    HGNC: 18150

    OMIM: 607295

    KEGG: hsa:84700

    STRING: 9606.ENSP00000334563

    UniGene: Hs.417959



主站蜘蛛池模板: 国产边摸边吃奶边做爽视频| 一本一本久久a久久综合精品 | 亚洲一区av无码专区在线观看| 色香欲综合成人免费视频| 欧美深度肠交惨叫| 开心五月色婷婷综合开心网| 午夜影视啪啪免费体验区入口| 久久综合a∨色老头免费观看| 色欲aⅴ 无码| 色噜噜狠狠狠狠色综合久一| 日本最新免费二区三区| 亚洲乱码一区二三四区ava| 中国内射xxxx6981少妇| 国产三级精品三级在线专区| 国产亚洲欧美在线专区| 中国国语毛片免费观看视频| 日韩理论午夜无码| 韩国无码色视频在线观看| 亚洲成av人片天堂网| 国产特级毛片aaaaaaa高清| 亚洲午夜精品a片久久www慈禧| 久久久噜噜噜久久熟女aa片| 免费观看男女性高视频| 国产精品无码一区二区三区在| 久久久性色精品国产免费观看| 色欲色香天天天综合无码| 992tv精品视频tv在线观看| 精品一区二区三区在线观看| 黑鬼大战白妞高潮喷白浆| 色偷偷av一区二区三区| 好男人www社区视频在线资源| 国内精品久久人妻互换| 夜夜嗨av一区二区三区| 亚洲综合精品伊人久久| 精品一卡2卡三卡4卡乱码精品视频| 四虎www成人影院观看| 久久久久成人精品无码| 成人做爰100部片免费下载 | 日韩少妇人妻vs中文字幕| 波多野结衣美乳人妻hd电影欧美| 无码人妻精品丰满熟妇区|