在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MYO18B Antibody

MYO18B Antibody

  • 中文名稱：
    MYO18B兔多克隆抗體
  • 貨號：
    CSB-PA142898
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA142898(MYO18B Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA142898(MYO18B Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    MYO18B
  • 別名：
    BK125H2.1 antibody; DKFZp434C2422 antibody; DKFZp779C1668 antibody; MY18B_HUMAN antibody; MYO18B antibody; myosin 18B antibody; myosin XVIIIB antibody; Myosin-XVIIIb antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthetic peptide of Human MYO18B
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth.
  • 基因功能參考文獻(xiàn)：
    1. Full loss of myo18b function results in a complete lack of sarcomeric structure, revealing a highly surprising and essential role for myo18b in sarcomere assembly. Importantly, scattered thin and thick filaments assemble throughout the sarcoplasm. These observations suggest a novel model of sarcomere assembly where Myo18b coordinates the integration of preformed thick and thin filaments into the sarcomere PMID: 28104788
    2. Deficiency of MYO18B is linked to a novel developmental disorder which combines KFA with myopathy. PMID: 25748484
    3. No associations were found between rs133885 in myosin-18B and mathematical abilities among individuals with dyslexia or in the general population. PMID: 25778778
    4. A common MYO18B variant is associated with mathematical disability in children with dyslexia and with intraparietal sulcus variability in neurotypical adults. PMID: 23423138
    5. candidate tumor suppressor gene at chromosome 22q12.1, deleted, mutated, and methylated in human lung cancer PMID: 12209013
    6. Human MYO18B, a novel unconventional myosin heavy chain expressed in striated muscles moves into the myonuclei upon differentiation PMID: 12547197
    7. MYO18B alterations, including both epigenetic and genetic alterations, play an important role in ovarian carcinogenesis PMID: 15305387
    8. Proteasome dysfunction by a proteasome inhibitor or siRNA-mediated knock-down of Sug1 caused the up-regulation of MYO18B protein and MYO18B was polyubiquitinated in vivo. PMID: 16499872
    9. The restored expression of MYO18B may be a useful therapeutic strategy for the treatment of locally advanced Malignant pleural mesothelioma(MPM)in humans. PMID: 17294804

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Klippel-Feil syndrome 4, autosomal recessive, with nemaline myopathy and facial dysmorphism (KFS4)
  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere. Note=Punctate pattern in undifferentiated myoblasts. Nuclear, on primary cardiomyocytes and adult muscle. A partial sarcomeric location was found in some cardiomyocytes.
  • 蛋白家族：
    TRAFAC class myosin-kinesin ATPase superfamily, Myosin family
  • 組織特異性：
    Selectively expressed in cardiac and skeletal muscles. Weakly expressed in testis, pancreas, placenta, prostate, lung and thymus.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 18150

    OMIM: 607295

    KEGG: hsa:84700

    STRING: 9606.ENSP00000334563

    UniGene: Hs.417959



主站蜘蛛池模板： 国产精品对白交换视频| av片在线观看永久免费| 天堂а√在线中文在线最新版| 秋霞午夜成人久久电影网| 色情无码一区二区三区| 亚洲精品av一二三区无码| 玩弄人妻少妇老师美妇厨房| 久久久久久a亚洲欧洲av冫| 国产午夜福利片| 国产精品亚洲专区无码影院| 国产国产裸模裸模私拍视频| 熟妇人妻一区二区三区四区| 国产婷婷一区二区三区| 久久綾合久久鬼色88| 亚洲狠亚洲狠亚洲狠狠狠| 欧美国产精品日韩在线| 亚洲欧洲日本无在线码| 亚洲制服丝袜自拍中文字幕| 日本三级香港三级三级人!妇久| 久久久久久av无码免费网站下载| 影音先锋在线亚洲网站| 国产偷国产偷亚洲清高网站| 黑人强辱丰满的人妻熟女| av淘宝国产在线观看| 中文字幕乱码久久午夜不卡| 国产性色播播毛片| √最新版天堂资源网在线| 99久久精品国产成人综合| 亚洲.日韩.欧美另类| 两个奶头被吃高潮视频| 国产青草视频在线观看| 日日日日做夜夜夜夜做无码| 九九re6热在线视频精品66| 国产精品对白交换视频| 蜜桃日本免费观看mv| 国产成人无码短视频| 亚洲欧美日韩综合一区二区| 老司机久久99久久精品播放免费| 奇米影视7777狠狠狠狠影视| 亚洲精品久久久久久久久久吃药| 亚洲精品制服丝袜四区|