在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Tyrosine-protein phosphatase non-receptor type 4 (PTPN4), partial

Recombinant Human Tyrosine-protein phosphatase non-receptor type 4 (PTPN4), partial

  • 中文名稱：
    人PTPN4重組蛋白
  • 貨號：
    CSB-YP019041HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人PTPN4重組蛋白
  • 貨號：
    CSB-EP019041HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人PTPN4重組蛋白
  • 貨號：
    CSB-EP019041HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人PTPN4重組蛋白
  • 貨號：
    CSB-BP019041HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人PTPN4重組蛋白
  • 貨號：
    CSB-MP019041HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    PTPN4
  • Uniprot No.：
  • 別名：
    MEG; megakaryocyte phosphatase; megakaryocyte protein-tyrosine phosphatase; Protein tyrosine phosphatase MEG1; Protein tyrosine phosphatase; megakaryocyte; protein tyrosine phosphatase; non-receptor type 4 (megakaryocyte); Protein-tyrosine phosphatase MEG1; PTN4; PTN4_HUMAN; PTPase MEG1; PTPase-MEG1; PTPMEG; PTPMEG1; Ptpn4; Tyrosine protein phosphatase non receptor type 4; Tyrosine-protein phosphatase non-receptor type 4
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Phosphatase that plays a role in immunity, learning, synaptic plasticity or cell homeostasis. Regulates neuronal cell homeostasis by protecting neurons against apoptosis. Negatively regulates TLR4-induced interferon beta production by dephosphorylating adapter TICAM2 and inhibiting subsequent TRAM-TRIF interaction. Dephosphorylates also the immunoreceptor tyrosine-based activation motifs/ITAMs of the TCR zeta subunit and thereby negatively regulates TCR-mediated signaling pathway. May act at junctions between the membrane and the cytoskeleton.
  • 基因功能參考文獻(xiàn)：
    1. Binding assays confirmed that three (Cyto8-mtxd-1, Cyto8-mtxk-4 and Cyto8-mtxd-1k-4) out of the five designed peptides exhibit moderately or considerably increased affinity as compared to the native peptide Cyto8-RETEV PMID: 27923202
    2. the p38gamma.PTPN4 interaction promotes cellular signaling, preventing cell death induction. PMID: 27246854
    3. Deletion of PTPN4 has been reported in monozygotic twins with a Rett syndrome-like phenotype. PMID: 25424712
    4. The physiologically active PTPN4 two-domain (the PDZ and the phosphatase domains) adopts a predominant compact conformation in solution. PDZ ligand binding restores the catalytic competence of PTPN4 disrupting the transient interdomain communication. PMID: 25158884
    5. These findings suggest that PTPN4 negatively regulates cell proliferation and motility through dephosphorylation of CrkI. PMID: 23666597
    6. PTPN4 is dispensable for T cell development and/or T cell effector functions. PMID: 18614237

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cytoplasm.
  • 蛋白家族：
    Protein-tyrosine phosphatase family, Non-receptor class subfamily
  • 數(shù)據(jù)庫鏈接：

    HGNC: 9656

    OMIM: 176878

    KEGG: hsa:5775

    STRING: 9606.ENSP00000263708

    UniGene: Hs.469809



主站蜘蛛池模板： 国产偷人妻精品一区| 日韩精品成人av在线观看| 精品国产亚洲一区二区三区在线观看| 久久国语露脸国产精品电影| 野狼第一精品社区| 国产漂亮白嫩美女在线观看| 亚洲国产欧美中文丝袜日韩| 精品久久人妻av中文字幕| 久久久久久国产精品无码超碰| 国产99在线 | 免费| 成在线人免费视频播放| 国产 亚洲 制服 无码 中文| 日韩综合夜夜香内射| av无码免费岛国动作片片段欣赏网| 久久不见久久见免费影院视频| 国产精品久久久久9999高清| 北条麻妃一区二区三区av高清| 欧洲一卡2卡3卡4卡国产| 国产精品99久久久久久宅男小说| 国内大量偷窥精品视频| 日日碰狠狠躁久久躁96avv| 四虎影在永久在线观看| 中文在线天堂а√在线| 亚洲色成人网一二三区| 亚洲国产成人精品无码区软件| 亚洲成在人网站无码天堂| 无尺码精品产品网站| 小嫩妇好紧好爽再快视频| 午夜在线看的免费网站| 午夜激成人免费视频在线观看| 日本熟妇大屁股人妻| 国产喷水1区2区3区咪咪爱av| 亚洲欧洲精品无码av| 国产偷窥熟女精品视频大全| 蜜臀av色欲a片无码精品一区| 国产一区二区三区在线视頻| 亚洲影院丰满少妇中文字幕无码| 久9re热视频这里只有精品| 亚洲色无码专线精品观看| 国产多人群p刺激交换视频| 国产精品视频|