在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PTPN4 Antibody

PTPN4 Antibody

  • 中文名稱：
    PTPN4兔多克隆抗體
  • 貨號：
    CSB-PA019041ESR1HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA019041ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA019041ESR1HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) PTPN4 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PTPN4
  • 別名：
    MEG antibody; megakaryocyte phosphatase antibody; megakaryocyte protein-tyrosine phosphatase antibody; Protein tyrosine phosphatase MEG1 antibody; Protein tyrosine phosphatase; megakaryocyte antibody; protein tyrosine phosphatase; non-receptor type 4 (megakaryocyte) antibody; Protein-tyrosine phosphatase MEG1 antibody; PTN4 antibody; PTN4_HUMAN antibody; PTPase MEG1 antibody; PTPase-MEG1 antibody; PTPMEG antibody; PTPMEG1 antibody; Ptpn4 antibody; Tyrosine protein phosphatase non receptor type 4 antibody; Tyrosine-protein phosphatase non-receptor type 4 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Tyrosine-protein phosphatase non-receptor type 4 protein (1-240AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Phosphatase that plays a role in immunity, learning, synaptic plasticity or cell homeostasis. Regulates neuronal cell homeostasis by protecting neurons against apoptosis. Negatively regulates TLR4-induced interferon beta production by dephosphorylating adapter TICAM2 and inhibiting subsequent TRAM-TRIF interaction. Dephosphorylates also the immunoreceptor tyrosine-based activation motifs/ITAMs of the TCR zeta subunit and thereby negatively regulates TCR-mediated signaling pathway. May act at junctions between the membrane and the cytoskeleton.
  • 基因功能參考文獻：
    1. Binding assays confirmed that three (Cyto8-mtxd-1, Cyto8-mtxk-4 and Cyto8-mtxd-1k-4) out of the five designed peptides exhibit moderately or considerably increased affinity as compared to the native peptide Cyto8-RETEV PMID: 27923202
    2. the p38gamma.PTPN4 interaction promotes cellular signaling, preventing cell death induction. PMID: 27246854
    3. Deletion of PTPN4 has been reported in monozygotic twins with a Rett syndrome-like phenotype. PMID: 25424712
    4. The physiologically active PTPN4 two-domain (the PDZ and the phosphatase domains) adopts a predominant compact conformation in solution. PDZ ligand binding restores the catalytic competence of PTPN4 disrupting the transient interdomain communication. PMID: 25158884
    5. These findings suggest that PTPN4 negatively regulates cell proliferation and motility through dephosphorylation of CrkI. PMID: 23666597
    6. PTPN4 is dispensable for T cell development and/or T cell effector functions. PMID: 18614237

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cytoplasm.
  • 蛋白家族：
    Protein-tyrosine phosphatase family, Non-receptor class subfamily
  • 數據庫鏈接：

    HGNC: 9656

    OMIM: 176878

    KEGG: hsa:5775

    STRING: 9606.ENSP00000263708

    UniGene: Hs.469809



主站蜘蛛池模板： 夜夜躁狠狠躁日日躁202| 久久精品国产免费观看| 国产毛多水多高潮高清| 亚洲中文字幕永久在线不卡| 亚洲 制服丝袜 中文字幕 在线| 鲁鲁狠狠狠7777一区二区| 国产成人av无码精品| 无码尹人久久相蕉无码| 中文国产成人精品久久久| 精品 在线 视频 亚洲| 国产成人免费无码视频在线观看| 欧美zozo另类特级| 成人国产一区二区三区精品不卡| 久久精品亚洲中文字幕无码网站 | 大香线蕉伊人精品超碰| 老男人久久青草av高清| 乌克兰美女浓毛bbw| 粉嫩小泬无遮挡久久久久久| 东北妇女精品bbwbbw| 丁香五月婷激情综合第九色| 亚洲国产制服丝袜高清在线| 日本亚洲欧洲无免费码在线| 人人妻人人澡人人爽欧美一区九九 | 国产精品无码制服丝袜| 久久亚洲精品无码播放| 无码制服丝袜人妻在线视频精品| 欧美人与性动交α欧美精品| 77777亚洲午夜久久多人| 久久婷婷丁香七月色综合| 中文字幕av无码一二三区电影| 深夜福利视频在线播放| 开心五月综合亚洲| 日本三级欧美三级人妇视频| 夜夜躁很很躁日日躁麻豆| 国产精品无码一区二区三区 | 日本丰满妇人成熟免费中文字幕| 少妇被黑人4p到惨叫欧美人| 中文字幕日韩人妻在线视频| 少妇性l交大片7724com| 中文字幕乱码一区二区免费| 久久久精品人妻无码专区不卡|