在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Tumor necrosis factor receptor superfamily member 27 (EDA2R), partial

Recombinant Human Tumor necrosis factor receptor superfamily member 27 (EDA2R), partial

  • 中文名稱：
    人EDA2R重組蛋白
  • 貨號：
    CSB-YP881011HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人EDA2R重組蛋白
  • 貨號：
    CSB-EP881011HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人EDA2R重組蛋白
  • 貨號：
    CSB-EP881011HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人EDA2R重組蛋白
  • 貨號：
    CSB-BP881011HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人EDA2R重組蛋白
  • 貨號：
    CSB-MP881011HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    EDA2R
  • Uniprot No.：
  • 別名：
    9430060M22Rik; Ectodysplasin A2 isoform receptor; Ectodysplasin A2 receptor; EDA A2R; EDA-A2 receptor; EDA2R; EDAA2R; MGC124099; OTTMUSP00000019574; OTTMUSP00000019575; RP23-188N15.1; TNFRSF27; TNR27_HUMAN; Tumor necrosis factor receptor superfamily member 27; Tumor necrosis factor receptor superfamily member XEDAR; X linked ectodysplasin A2 receptor; X linked ectodysplasin receptor; X-linked ectodysplasin-A2 receptor; XEDAR
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Receptor for EDA isoform A2, but not for EDA isoform A1. Mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be mediated by binding to TRAF3 and TRAF6.
  • 基因功能參考文獻：
    1. We found evidence for AR but not EDA2R as the candidate gene at the androgenetic alopecia risk locus on chromosome X. PMID: 27060448
    2. EDA-A2 and its receptor XEDAR are overexpressed in epithelial cells of salivary glands in Sjogren's syndrome patients, in comparison with healthy individuals. The EDA-A2/XEDAR system in these cells is involved in the induction of apoptosis via CASP3 activation. PMID: 26659383
    3. XEDAR activates the non-canonical NF-kappaB pathway. PMID: 26260321
    4. To investigate the evolutionary history of the EDA2R/AR intergenic region, we characterized the haplotype structure of 52 of its highly differentiated SNPs. Nearly all human X chromosomes carry one of two modal haplotypes for these 52 SNPs. PMID: 23959643
    5. The results suggest that EDA2R confers susceptibility to early onset female pattern hair loss PMID: 22309448
    6. association in dental crowding in the Hong Kong Chinese population PMID: 21724072
    7. A crucial role of the EDA-A2/ectodysplasin A2 (XEDAR) interaction is revealed in the p53-signaling pathway. PMID: 20501644
    8. because no frequent variant other than rs1385699 has been reported in EDA2R in the European population, it is probable that the causative variant(s) modifies the expression of one or more flanking genes, i.e. AR and EDA2R PMID: 20199557
    9. Results establish a major role of TRAF3 and -6 in X-linked ectodermal dysplasia receptor (XEDAR) signaling and in the process of ectodermal differentiation. PMID: 12270937
    10. XEDAR belongs to a novel class of death receptors that lack a discernible death domain but are capable of activating apoptosis in a caspase 8- and FADD-dependent fashion PMID: 15280356
    11. isoforms of EDA-A5 and A5',activated NF-kappaB through receptors EDAR and XEDAR PMID: 16423472
    12. The androgen receptor gene and EDA2R are significantly associated with androgenetic alopecia. PMID: 18385763
    13. androgen receptor/ectodysplasin A2 receptor haplotype may have a role in male pattern baldness PMID: 19373488
    14. XEDAR is a putative tumor suppressor that could prevent malignant transformation and tumor progression by regulating apoptosis and anoikis. PMID: 19543321

    顯示更多

    收起更多

  • 亞細胞定位：
    Membrane; Single-pass type III membrane protein.
  • 數據庫鏈接：

    HGNC: 17756

    OMIM: 300276

    KEGG: hsa:60401

    UniGene: Hs.302017



主站蜘蛛池模板： 国产精品白浆在线观看免费 | 粗大的内捧猛烈进出看视频| 国产国拍精品av在线观看按摩 | 国产乱人伦偷精品视频| 三上悠亚精品一区二区久久| 最近日本mv字幕免费高清完整版| 亚洲高清国产拍精品闺蜜合租| 蜜臀av在线播放一区二区三区| 欧美精品中文字幕亚洲专区| 无码三级国产三级在线电影| 亚洲欧美日韩中字视频三区| 国内熟妇人妻色无码视频在线| 亚洲女同一区二区| 中文字幕亚洲无线码在线一区| 高潮内射免费看片| 狠狠色噜噜狠狠狠8888在| 可以免费观看的av毛片下载| 久久天天躁狠狠躁夜夜网站| 国产又色又爽又黄的在线观看视频| 4hu四虎永久在线影院| 麻豆md0077饥渴少妇| 亚洲精品一品区二品区三品区 | 国产精品美女久久久m| 老司机在线精品视频播放| 无码人妻啪啪一区二区| 一本大道久久东京热av| 日本丰满人妻xxxxxhd| 国产精品特级毛片一区二区三区 | 国内无遮挡18禁无码网站免费| 潮喷大喷水系列无码| 桃花色综合影院| 国产av精品毛片一区二区三区 | 欧美人伦禁忌dvd放荡欲情| 无码人妻av一二区二区三区| 国内精品美女视频免费直播| 亚洲国产制服丝袜高清在线| 少妇太爽了在线观看| 久久精品国产久精国产一老狼| 中文无码第3页不卡av| 免费做a爰片久久毛片a片| 久久亚洲一区二区三区四区五区|