在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. EDA2R Antibody

EDA2R Antibody

  • 中文名稱：
    EDA2R兔多克隆抗體
  • 貨號(hào)：
    CSB-PA025575
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA025575(EDA2R Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA025575(EDA2R Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: 293T cells, Primary antibody: CSB-PA025575(EDA2R Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    EDA2R
  • 別名：
    9430060M22Rik antibody; Ectodysplasin A2 isoform receptor antibody; Ectodysplasin A2 receptor antibody; EDA A2R antibody; EDA-A2 receptor antibody; EDA2R antibody; EDAA2R antibody; MGC124099 antibody; OTTMUSP00000019574 antibody; OTTMUSP00000019575 antibody; RP23-188N15.1 antibody; TNFRSF27 antibody; TNR27_HUMAN antibody; Tumor necrosis factor receptor superfamily member 27 antibody; Tumor necrosis factor receptor superfamily member XEDAR antibody; X linked ectodysplasin A2 receptor antibody; X linked ectodysplasin receptor antibody; X-linked ectodysplasin-A2 receptor antibody; XEDAR antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Fusion protein of Human EDA2R
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:200-1:1000
    IHC 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Receptor for EDA isoform A2, but not for EDA isoform A1. Mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be mediated by binding to TRAF3 and TRAF6.
  • 基因功能參考文獻(xiàn)：
    1. We found evidence for AR but not EDA2R as the candidate gene at the androgenetic alopecia risk locus on chromosome X. PMID: 27060448
    2. EDA-A2 and its receptor XEDAR are overexpressed in epithelial cells of salivary glands in Sjogren's syndrome patients, in comparison with healthy individuals. The EDA-A2/XEDAR system in these cells is involved in the induction of apoptosis via CASP3 activation. PMID: 26659383
    3. XEDAR activates the non-canonical NF-kappaB pathway. PMID: 26260321
    4. To investigate the evolutionary history of the EDA2R/AR intergenic region, we characterized the haplotype structure of 52 of its highly differentiated SNPs. Nearly all human X chromosomes carry one of two modal haplotypes for these 52 SNPs. PMID: 23959643
    5. The results suggest that EDA2R confers susceptibility to early onset female pattern hair loss PMID: 22309448
    6. association in dental crowding in the Hong Kong Chinese population PMID: 21724072
    7. A crucial role of the EDA-A2/ectodysplasin A2 (XEDAR) interaction is revealed in the p53-signaling pathway. PMID: 20501644
    8. because no frequent variant other than rs1385699 has been reported in EDA2R in the European population, it is probable that the causative variant(s) modifies the expression of one or more flanking genes, i.e. AR and EDA2R PMID: 20199557
    9. Results establish a major role of TRAF3 and -6 in X-linked ectodermal dysplasia receptor (XEDAR) signaling and in the process of ectodermal differentiation. PMID: 12270937
    10. XEDAR belongs to a novel class of death receptors that lack a discernible death domain but are capable of activating apoptosis in a caspase 8- and FADD-dependent fashion PMID: 15280356
    11. isoforms of EDA-A5 and A5',activated NF-kappaB through receptors EDAR and XEDAR PMID: 16423472
    12. The androgen receptor gene and EDA2R are significantly associated with androgenetic alopecia. PMID: 18385763
    13. androgen receptor/ectodysplasin A2 receptor haplotype may have a role in male pattern baldness PMID: 19373488
    14. XEDAR is a putative tumor suppressor that could prevent malignant transformation and tumor progression by regulating apoptosis and anoikis. PMID: 19543321

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Membrane; Single-pass type III membrane protein.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 17756

    OMIM: 300276

    KEGG: hsa:60401

    UniGene: Hs.302017



主站蜘蛛池模板： 护士奶头又大又软又好摸| 精品无码久久久久久久久久| 国产精品久久婷婷六月丁香 | 婷婷色怡春院| 国产精品www夜色视频| 奇米影视7777久久精品人人爽| 国产一区二区三区在线蜜桃| 精品一区二区三区无码免费直播 | 亚洲精品日本一区二区三区| 麻豆一区二区99久久久久 | 天天爽天天狠久久久综合麻豆| 中文在线а√在线| 一个添下面两个吃奶把腿扒开 | 国产亚洲香蕉线播放αv38| 国产精品爱久久久久久久| 欧美性黑人极品hd| 久久一日本综合色鬼综合色| 久久精品亚洲国产av老鸭网| 亚洲欧美一区二区成人片| 少妇激情一区二区三区视频 | 亚洲中文字幕精品久久久久久动漫| 成人动漫综合网| 99热精品毛片全部国产无缓冲| 无码少妇一区二区三区浪潮av| 国产永久免费观看视频| 久久久久久免费毛片精品| 久久精品国产精品国产精品污| 99热成人精品国产免费| 免费无遮挡很爽很污很黄的网站| 在线中文新版最新版在线 | 日本高清一二三不卡区| 99久久婷婷国产综合精品电影| 亚洲区小说区图片区qvod| 色哟哟最新在线观看入口| 夜夜精品无码一区二区三区| 少妇熟女视频一区二区三区| 国产精品麻豆欧美日韩ww| 欧美乱码卡一卡二卡三新区| 久久久久久无码精品人妻a片软件| 久久九九有精品国产23百花影院 | 中文字幕有码无码人妻在线|