在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. EDA2R Antibody

EDA2R Antibody

  • 中文名稱：
    EDA2R兔多克隆抗體
  • 貨號(hào)：
    CSB-PA025575
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA025575(EDA2R Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA025575(EDA2R Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: 293T cells, Primary antibody: CSB-PA025575(EDA2R Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    EDA2R
  • 別名：
    9430060M22Rik antibody; Ectodysplasin A2 isoform receptor antibody; Ectodysplasin A2 receptor antibody; EDA A2R antibody; EDA-A2 receptor antibody; EDA2R antibody; EDAA2R antibody; MGC124099 antibody; OTTMUSP00000019574 antibody; OTTMUSP00000019575 antibody; RP23-188N15.1 antibody; TNFRSF27 antibody; TNR27_HUMAN antibody; Tumor necrosis factor receptor superfamily member 27 antibody; Tumor necrosis factor receptor superfamily member XEDAR antibody; X linked ectodysplasin A2 receptor antibody; X linked ectodysplasin receptor antibody; X-linked ectodysplasin-A2 receptor antibody; XEDAR antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Fusion protein of Human EDA2R
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:200-1:1000
    IHC 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Receptor for EDA isoform A2, but not for EDA isoform A1. Mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be mediated by binding to TRAF3 and TRAF6.
  • 基因功能參考文獻(xiàn)：
    1. We found evidence for AR but not EDA2R as the candidate gene at the androgenetic alopecia risk locus on chromosome X. PMID: 27060448
    2. EDA-A2 and its receptor XEDAR are overexpressed in epithelial cells of salivary glands in Sjogren's syndrome patients, in comparison with healthy individuals. The EDA-A2/XEDAR system in these cells is involved in the induction of apoptosis via CASP3 activation. PMID: 26659383
    3. XEDAR activates the non-canonical NF-kappaB pathway. PMID: 26260321
    4. To investigate the evolutionary history of the EDA2R/AR intergenic region, we characterized the haplotype structure of 52 of its highly differentiated SNPs. Nearly all human X chromosomes carry one of two modal haplotypes for these 52 SNPs. PMID: 23959643
    5. The results suggest that EDA2R confers susceptibility to early onset female pattern hair loss PMID: 22309448
    6. association in dental crowding in the Hong Kong Chinese population PMID: 21724072
    7. A crucial role of the EDA-A2/ectodysplasin A2 (XEDAR) interaction is revealed in the p53-signaling pathway. PMID: 20501644
    8. because no frequent variant other than rs1385699 has been reported in EDA2R in the European population, it is probable that the causative variant(s) modifies the expression of one or more flanking genes, i.e. AR and EDA2R PMID: 20199557
    9. Results establish a major role of TRAF3 and -6 in X-linked ectodermal dysplasia receptor (XEDAR) signaling and in the process of ectodermal differentiation. PMID: 12270937
    10. XEDAR belongs to a novel class of death receptors that lack a discernible death domain but are capable of activating apoptosis in a caspase 8- and FADD-dependent fashion PMID: 15280356
    11. isoforms of EDA-A5 and A5',activated NF-kappaB through receptors EDAR and XEDAR PMID: 16423472
    12. The androgen receptor gene and EDA2R are significantly associated with androgenetic alopecia. PMID: 18385763
    13. androgen receptor/ectodysplasin A2 receptor haplotype may have a role in male pattern baldness PMID: 19373488
    14. XEDAR is a putative tumor suppressor that could prevent malignant transformation and tumor progression by regulating apoptosis and anoikis. PMID: 19543321

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Membrane; Single-pass type III membrane protein.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 17756

    OMIM: 300276

    KEGG: hsa:60401

    UniGene: Hs.302017



主站蜘蛛池模板： 色屁屁www影院免费观看入口| 在线观看国产丝袜控网站| 极品少妇伦理一区二区| 无码人妻丰满熟妇奶水区码| 国产v亚洲v天堂a无码| 人妻另类 专区 欧美 制服| 色多多www视频在线观看免费| 国产日韩未满十八禁止观看| 99久久国产成人免费网站| 无码人妻一区二区三区av | 成 人影片 免费观看在线| 国产尤物在线视精品在亚洲| 亚洲伊人成无码综合网| 欧美亚洲国产精品久久高清| 亚洲区欧美区综合区自拍区| 老汉色老汉首页a亚洲| 欧美黑人xxxx性高清版| 波多野结衣一区二区三区av高清| 日韩人妻熟女中文字幕a美景之屋| 国产精品有码无码av在线播放| 色偷偷亚洲精品一区二区| 国语自产精品视频在线第100页| 久久久久黑人强伦姧人妻| 麻批好紧日起要舒服死了| 卡1卡2卡3精品接入口| 日韩欧美激情兽交| 人妻少妇精品无码专区动漫| 国内少妇偷人精品免费| 99久热re在线精品视频| 边喂奶边中出的人妻| 亚洲精华国产精华精华液网站| 69久久国产露脸精品国产| 免费网禁国产you女网站下载| 熟妇的奶头又大又长奶水视频| 艳妇臀荡乳欲伦交换h在线观看 | 欧美精品欧美人与动人物牲交| 亚洲精品一区二区中文字幕| 日日躁夜夜躁狠狠久久av| 起碰免费公开97在线视频| 东京热一精品无码av| 中文字幕久久久久人妻|