在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Thyroxine-binding globulin (SERPINA7 TBG)

Recombinant Human Thyroxine-binding globulin (SERPINA7 TBG)

  • 中文名稱：
  • 貨號：
    CSB-YP021063HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
  • 貨號：
    CSB-EP021063HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
  • 貨號：
    CSB-EP021063HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
  • 貨號：
    CSB-BP021063HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
  • 貨號：
    CSB-MP021063HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    THBG
  • Uniprot No.：
  • 別名：
    Thyroxine-binding globulin; Serpin A7; T4-binding globulin; SERPINA7 TBG
  • 種屬：
    Homo sapiens (Human)
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Major thyroid hormone transport protein in serum.
  • 基因功能參考文獻：
    1. A new SERPINA7 variant associated with thyroxine-binding globulin deficiency in three siblings. PMID: 29733970
    2. THBG is a potential plasma biomarker for COPD. PMID: 28579773
    3. mutation in a liver-specific enhancer region of the TBG gene caused inherited TBG deficiency. To our knowledge, the present study is the first report of an inherited endocrine disorder caused by a mutation in an enhancer region. PMID: 25361180
    4. TBG allosteric regulation is entropy driven. The presence of multiple S states may allow more efficient T4 release due to protease activity. PMID: 23458682
    5. the TBG promoter has a role in sustaining transgene expression in liver-specific pattern PMID: 22820390
    6. Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins. PMID: 21325280
    7. Freshly isolated TBG-Chicago exists in loop expelled conformation. At 37C, the protein readily converts to a more stable loop inserted conformation with enhanced heat stability. PMID: 20429632
    8. an intragenic A/G polymorphism (125 bp upstream from exon 2) was identified. complete TBG deficiency was homozygous for the polymorphic TBG allele. PMID: 11889160
    9. Two novel variants in the thyroxine-binding globulin gene behind the diagnosis of TBG deficiency. homozygous. One involved codon 23 (TCA-->TAA) and the other, codon 223. PMID: 11916615
    10. Loop variants of the serpin thyroxine-binding globulin: implications for hormone release upon limited proteolysis. PMID: 11931635
    11. guanine deletion at position 1711, codon 201 (Asp) in exon 2 (GAC --> AC) led to a frame shift and premature termination at codon 206, causing a short TBG protein of 205 amino acids (AA) compared to 395 AA of the normal TBG. PMID: 17887925
    12. new serpina7 gene variant in three members of the same family results in the replacement of the normal asparagine 233 by isoleucine and, subsequently, in disruption of a glycosylation site PMID: 19415532
    13. The first exon (exon 0) is a short noncoding sequence located 1.62 kilobase pairs (kbp) upstream from exon 1. HNF-1 site (located 65 bp upstream of the TSS) is required for the hepatocyte specific expression of the hTBG gene. PMID: 8232304

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Serpin family
  • 組織特異性：
    Expressed by the liver and secreted in plasma.
  • 數據庫鏈接：

    HGNC: 11583

    OMIM: 300932

    KEGG: hsa:6906

    STRING: 9606.ENSP00000329374

    UniGene: Hs.76838



主站蜘蛛池模板： 成人做爰100部片免费下载| 欧美激情综合五月色丁香| 女人裸体性做爰视频| 99久久国产露脸精品国产麻豆| 日本japanese丰满多毛| 亚洲国产精品一区二区成人片国内| 少妇扒开粉嫩小泬视频| 国产成人综合久久三区| 欧美精品1卡二卡三卡四卡| 日本免费高清线视频免费| 日本视频高清一道一区| 国产成人综合久久三区| ww欧日韩视频高清在线| 国模杨依粉嫩蝴蝶150p| 国精产品一品二品国精品69xx| 中文字幕人妻被公上司喝醉在线| 爆乳高潮喷水无码正在播放| 国产精品久久| 推油少妇久久99久久99久久| 国产高潮抽搐喷水高清| 2021麻豆剧传媒一二三区| 在线成人一区二区| 亚洲午夜精品a片久久www慈禧| 午夜成人无码片在线观看影院| 任我爽橹在线视频精品583| 牛牛视频一区二区三区| 亚洲成h人av无码动漫无遮挡| 中文字幕亚洲男人的天堂网络| 国产又色又爽又黄的免费| 精品久久人人妻人人做精品| 97一期涩涩97片久久久久久久| 一区二区三区av高清免费波多| 国产精品国产高清国产av| 一本一道av无码中文字幕| 午夜免费啪视频在线观看区| 中文字幕被公侵犯的漂亮人妻| 欧洲熟妇牲交| 久久久久久久精品成人执小说一白| 精品无码成人片一区二区98| 无码国产精成人午夜视频一区二区| 国产成人无码免费视频麻豆 |