在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SERPINA7 Antibody

SERPINA7 Antibody

  • 中文名稱：
    SERPINA7兔多克隆抗體
  • 貨號：
    CSB-PA783838
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA783838(SERPINA7 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA783838(SERPINA7 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    Serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 7 antibody; Serpin A7 antibody; Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 7 antibody; Serpin peptidase inhibitor, clade A, member 7 antibody; Serpina7 antibody; T4 binding globulin antibody; TBG antibody; TBG, serum antibody; THBG_HUMAN antibody; Thyroxin binding globulin antibody; Thyroxine binding globulin antibody; Thyroxine-binding globulin antibody; Thyroxine-binding globulin od serum antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Full length fusion protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Major thyroid hormone transport protein in serum.
  • 基因功能參考文獻：
    1. A new SERPINA7 variant associated with thyroxine-binding globulin deficiency in three siblings. PMID: 29733970
    2. THBG is a potential plasma biomarker for COPD. PMID: 28579773
    3. mutation in a liver-specific enhancer region of the TBG gene caused inherited TBG deficiency. To our knowledge, the present study is the first report of an inherited endocrine disorder caused by a mutation in an enhancer region. PMID: 25361180
    4. TBG allosteric regulation is entropy driven. The presence of multiple S states may allow more efficient T4 release due to protease activity. PMID: 23458682
    5. the TBG promoter has a role in sustaining transgene expression in liver-specific pattern PMID: 22820390
    6. Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins. PMID: 21325280
    7. Freshly isolated TBG-Chicago exists in loop expelled conformation. At 37C, the protein readily converts to a more stable loop inserted conformation with enhanced heat stability. PMID: 20429632
    8. an intragenic A/G polymorphism (125 bp upstream from exon 2) was identified. complete TBG deficiency was homozygous for the polymorphic TBG allele. PMID: 11889160
    9. Two novel variants in the thyroxine-binding globulin gene behind the diagnosis of TBG deficiency. homozygous. One involved codon 23 (TCA-->TAA) and the other, codon 223. PMID: 11916615
    10. Loop variants of the serpin thyroxine-binding globulin: implications for hormone release upon limited proteolysis. PMID: 11931635
    11. guanine deletion at position 1711, codon 201 (Asp) in exon 2 (GAC --> AC) led to a frame shift and premature termination at codon 206, causing a short TBG protein of 205 amino acids (AA) compared to 395 AA of the normal TBG. PMID: 17887925
    12. new serpina7 gene variant in three members of the same family results in the replacement of the normal asparagine 233 by isoleucine and, subsequently, in disruption of a glycosylation site PMID: 19415532
    13. The first exon (exon 0) is a short noncoding sequence located 1.62 kilobase pairs (kbp) upstream from exon 1. HNF-1 site (located 65 bp upstream of the TSS) is required for the hepatocyte specific expression of the hTBG gene. PMID: 8232304

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Serpin family
  • 組織特異性：
    Expressed by the liver and secreted in plasma.
  • 數據庫鏈接：

    HGNC: 11583

    OMIM: 300932

    KEGG: hsa:6906

    STRING: 9606.ENSP00000329374

    UniGene: Hs.76838



主站蜘蛛池模板： 久久久亚洲欧洲日产国产成人无码 | 国产9 9在线 | 中文| 狠狠色成人综合网| 欧美牲交视频免费观看| 久久99精品久久久久久hb亚瑟| 双乳奶水饱满少妇呻吟| 亚洲成色www久久网站| 久久精品中文闷骚内射| 国产精品久久自在自线青柠| 国产午夜精华2020在线| 免费大片av手机看片不卡| 亚洲国产丝袜精品一区| 无码办公室丝袜ol中文字幕| 亚洲国产成人精品无码区99| 欧亚精品一区三区免费| 色悠久久久久综合先锋影音下载 | 肉感饱满中年熟妇日本| av永久天堂一区| 蜜桃视频无码区在线观看| 国产 一二三四五六| 天天澡天天揉揉av无码| 国产肉丝袜在线观看| 无码视频在线观看| 国产尤物精品视频| 日本少妇肉体裸交xxx| 乱无码伦视频在线观看| 中国精学生妹品射精久久| 日韩精品成人无码专区免费| 亚洲精品一区国产| 久久久久亚洲精品天堂| 韩日综合成人中文字幕| 欧美国产精品日韩在线| 亚洲熟妇无码久久精品| 无码福利在线观看1000集| 欧美日韩中文国产一区发布| 国模欢欢炮交啪啪150| 亚洲2021av天堂手机版| 国产成人精品a视频免费福利| 国产精品久久久影视青草| 中国熟妇牲交视频| 偷窥村妇洗澡毛毛多|