在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Tax1-binding protein 3 (TAX1BP3)

  • 中文名稱:
    人TAX1BP3重組蛋白
  • 貨號:
    CSB-RP044454h
  • 規格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    Glutaminase interacting protein 3; Glutaminase-interacting protein 3; Tax interaction protein 1; Tax1 (human T cell leukemia virus type I) binding protein 3; Tax1 binding protein 3; Tax1-binding protein 3; Tax1bp3; TIP 1; TIP-1; TIP1; TX1B3_HUMAN
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length
  • 來源:
    E.coli
  • 分子量:
    40.7kDa
  • 表達區域:
    1-124aa
  • 氨基酸序列
    MSYIPGQPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQSLQKAVQQSMLS
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal GST-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6.
  • 基因功能參考文獻:
    1. Mutations in TAX1BP3 cause dilated cardiomyopathy with septo-optic dysplasia PMID: 25645515
    2. ARHGEF7, a guanine nucleotide exchange factor for Rho GTPases, as one novel TIP-1-interacting protein in human glioblastoma cells PMID: 23563176
    3. this study reports the identification of two new hGIP-interacting partners, DTX1 and STAU1. PMID: 23395680
    4. The study provided the first evidence showing that TIP-1 modulates p53 protein stability and is involved in the radioresistance of malignant gliomas. PMID: 23028987
    5. The study reports the identification of 18 new glutaminase-interacting protein - binding peptides with novel internal motifs that map to a number of candidate human glutaminase-interacting protein partner proteins. PMID: 22876914
    6. this study revealed a novel oncogenic function of TIP-1 suggesting that TIP-1 holds potential as a prognostic biomarker and a therapeutic target in the treatment of human invasive breast cancers. PMID: 22564736
    7. HPV16 E6, Tip-1 and ARHGEF16 may cooperate to activate Cdc42 and support a potential link between the expression of HPV16 E6 and Cdc42 activation. PMID: 21139582
    8. This is the first study reporting BAI2 as an interaction partner of GIP. PMID: 21787750
    9. TIP-1 may represent a novel regulatory element in the Wnt/beta-catenin signaling pathway PMID: 12874278
    10. HPV16 E6 protein may increase cell motility by augmenting GTP RhoA mediated activation of RhoA kinases and that this is dependent on the expression of the Tip-1 protein PMID: 15492812
    11. TIP-1 is ubiquitously expressed, raising the possibility that TIP-1 may play a similar role in regulating the expression of other membrane proteins containing a type I PDZ ligand. PMID: 16855024
    12. the overexpression, efficient refolding, single-step purification, and biophysical characterization of recombinant human TIP-1 with three different C-terminal target protein recognition sequence motifs by CD, fluorescence, and NMR methods PMID: 18690705
    13. TIP-1 may act as an important regulator for the endocytic pathway of Kir2.3. PMID: 19635485

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Recruited to the cell membrane by interaction with membrane proteins.
  • 組織特異性:
    Ubiquitous. Detected in brain, heart, kidney, lung, small intestine and skeletal muscle. Detected in various cell lines including HeLa. Weakly expressed in peripheral blood leukocytes.
  • 數據庫鏈接:

    HGNC: 30684

    OMIM: 616476

    KEGG: hsa:30851

    STRING: 9606.ENSP00000225525

    UniGene: Hs.12956



主站蜘蛛池模板: 窝窝午夜精品一区二区| 国产精品久久久爽爽爽麻豆色哟哟| 法国伦理少妇愉情| 少妇高潮av久久久久久| 中出内射颜射骚妇| 久久日本三级韩国三级| 欧洲av成本人在线观看免费| 伊人成伊人成综合网222| 亚洲狠狠做深爱婷婷影院| 色欲狠狠躁天天躁无码中文字幕| 性乌克兰xxxx极品| 视频在线+欧美十亚洲曰本| 国产精品久久久久久日本| 欧洲国产精品无码专区影院| 一本色道久久99一综合| 亚洲国产精品无码久久98| 国产69久久精品成人看| 九月婷婷人人澡人人添人人爽| 国内精品久久久久久久97牛牛| 在线亚洲97se亚洲综合在线| 国产嘿嘿嘿视频在线观看| 欧美亚洲色欲色一欲www| 日韩一区二区三区无码人妻视频| 亚洲一区二区三区影院| 午夜精品久久久久久久久 | 99久久精品免费看国产一区二区| 免费人成网视频在线观看| 丰满少妇被猛烈进av毛片| 久久这里只有精品首页| 亚洲日韩精品一区二区三区无码| 色丁狠狠桃花久久综合网| 4hu亚洲人成人无码网www电影首页| 国产成人精品亚洲线观看| 无码人妻丰满熟妇精品区| 日韩精品一区二区大桥未久| 亚洲欧洲精品成人久久曰影片| 伊人www22综合色| 青青国产揄拍视频| 视频二区丝袜国产欧美日韩| 日日碰狠狠躁久久躁综合小说| 成人午夜又粗又硬又长|