在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TAX1BP3 Antibody

TAX1BP3 Antibody

  • 中文名稱：
    TAX1BP3兔多克隆抗體
  • 貨號：
    CSB-PA023180GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    Glutaminase interacting protein 3 antibody; Glutaminase-interacting protein 3 antibody; Tax interaction protein 1 antibody; Tax1 (human T cell leukemia virus type I) binding protein 3 antibody; Tax1 binding protein 3 antibody; Tax1-binding protein 3 antibody; Tax1bp3 antibody; TIP 1 antibody; TIP-1 antibody; TIP1 antibody; TX1B3_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human TAX1BP3
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6.
  • 基因功能參考文獻：
    1. Mutations in TAX1BP3 cause dilated cardiomyopathy with septo-optic dysplasia PMID: 25645515
    2. ARHGEF7, a guanine nucleotide exchange factor for Rho GTPases, as one novel TIP-1-interacting protein in human glioblastoma cells PMID: 23563176
    3. this study reports the identification of two new hGIP-interacting partners, DTX1 and STAU1. PMID: 23395680
    4. The study provided the first evidence showing that TIP-1 modulates p53 protein stability and is involved in the radioresistance of malignant gliomas. PMID: 23028987
    5. The study reports the identification of 18 new glutaminase-interacting protein - binding peptides with novel internal motifs that map to a number of candidate human glutaminase-interacting protein partner proteins. PMID: 22876914
    6. this study revealed a novel oncogenic function of TIP-1 suggesting that TIP-1 holds potential as a prognostic biomarker and a therapeutic target in the treatment of human invasive breast cancers. PMID: 22564736
    7. HPV16 E6, Tip-1 and ARHGEF16 may cooperate to activate Cdc42 and support a potential link between the expression of HPV16 E6 and Cdc42 activation. PMID: 21139582
    8. This is the first study reporting BAI2 as an interaction partner of GIP. PMID: 21787750
    9. TIP-1 may represent a novel regulatory element in the Wnt/beta-catenin signaling pathway PMID: 12874278
    10. HPV16 E6 protein may increase cell motility by augmenting GTP RhoA mediated activation of RhoA kinases and that this is dependent on the expression of the Tip-1 protein PMID: 15492812
    11. TIP-1 is ubiquitously expressed, raising the possibility that TIP-1 may play a similar role in regulating the expression of other membrane proteins containing a type I PDZ ligand. PMID: 16855024
    12. the overexpression, efficient refolding, single-step purification, and biophysical characterization of recombinant human TIP-1 with three different C-terminal target protein recognition sequence motifs by CD, fluorescence, and NMR methods PMID: 18690705
    13. TIP-1 may act as an important regulator for the endocytic pathway of Kir2.3. PMID: 19635485

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Recruited to the cell membrane by interaction with membrane proteins.
  • 組織特異性：
    Ubiquitous. Detected in brain, heart, kidney, lung, small intestine and skeletal muscle. Detected in various cell lines including HeLa. Weakly expressed in peripheral blood leukocytes.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 30684

    OMIM: 616476

    KEGG: hsa:30851

    STRING: 9606.ENSP00000225525

    UniGene: Hs.12956



主站蜘蛛池模板： 中文无码日韩欧av影视| 中文字幕乱码人妻二区三区| 妇女性内射冈站hdwww000| 国产国拍精品av在线观看| 亚洲午夜理论片在线观看| 亚洲色无码专区一区| 人人妻人人爽人人爽| 五月天激情国产综合婷婷婷| 国产高清在线精品一区| 欧美疯狂性受xxxxx喷水| 国产后进白嫩翘臀在线播放| 久久久亚洲欧洲日产av| 亚洲中文无码av永久伊人| 久久久久久久精品成人热色戒汤唯| 巨人精品福利官方导航| 内射毛片内射国产夫妻| 天堂а√在线最新版中文| 内射一区二区精品视频在线观看| 99精品免视看| 人人超碰人人爱超碰国产 | 午夜性开放午夜性爽爽| 亚洲孰妇无码av在线播放| 无遮挡免费高清羞羞视频| 色狠狠av老熟女| 高清一区二区三区日本久| 国产精品高清一区二区不卡片| 无码帝国www无码专区色综合 | 免费无码av片在线观看潮喷| 色情无码www视频无码区澳门| 亚洲肥老太bbw中国熟女| 亚洲精品一区久久久久一品av| 7m精品福利视频导航| 国内精品久久久久影院网站| 熟妇人妻无乱码中文字幕| 亚洲成a人片在线观看www| 女人18毛片水真多免费看| 亚洲开心婷婷中文字幕| 欧美xxxx做受欧美88| 亚洲国产aⅴ成人精品无吗 | 亚洲中文字幕久久无码| 国内揄拍国内精品人妻浪潮av|